Down Syndrome — How Stuttering and Gestures Influence the Intelligibility of Individuals With Down Syndrome
Citation(s)
Arenas, R M. Conceptualizing and investigating the contextual variability of stuttering: The speech and monitoring interaction (SAMI) framework. Speech, Lang. Hear. 20, 15-28 (2017).
Chapman RS (1997) Language development in children and adolescents with Down syndrome. Ment Retard Develop Dis Res Rev. 1997; 3: 307-312.
Chapman RS Language learning in Down syndrome: the speech and language profile compared to adolescents with cognitive impairment of unknown origin. Downs Syndr Res Pract. 2006 Jul;10(2):61-6.
Clibbens, J & Powell, G. Actions speak louder than words: signing and speech intelligibility in adults with Down syndrome. Down Syndr. Res. Pract. 2, 127-129 (2007).
Eggers K, Van Eerdenbrugh S Speech disfluencies in children with Down Syndrome. J Commun Disord. 2018 Jan - Feb;71:72-84. doi: 10.1016/j.jcomdis.2017.11.001. Epub 2017 Nov 8.
Fletcher P, Macwhinney B, editors The handbook of child language. Oxford,UK:Blackwell; c1995. 800 p. (Chapman RS, editor. Language development in children and adolescents with Down syndrome; vol. 3).
Galeote M, Sebastián E, Checa E, Rey R, Soto P The development of vocabulary in Spanish children with Down syndrome: comprehension, production, and gestures. J Intellect Dev Disabil. 2011 Sep;36(3):184-96. doi: 10.3109/13668250.2011.599317.
Garcia JM, Cannito MP Influence of verbal and nonverbal contexts on the sentence intelligibility of a speaker with dysarthria. J Speech Hear Res. 1996 Aug;39(4):750-60.
Greenwald CA, Leonard LB Communicative and sensorimotor development of Down's syndrome children. Am J Ment Defic. 1979 Nov;84(3):296-303.
Guitar B Stuttering. An integrated approach to its nature and treatment.3re ed. Baltimore: Lippincott, Williams & Wilkins; 2006. 376 p.
Hammond G, editor Cerebral control of speech and limb movements. Amsterdam: North-Holland; c1990. 708 p. (Flanagan R, Feldman, A, Ostry. Control of human jaw and multi-joint arm movements; vol.1).
Kent RD, Vorperian HK Speech impairment in Down syndrome: a review. J Speech Lang Hear Res. 2013 Feb;56(1):178-210. doi: 10.1044/1092-4388(2012/12-0148). Epub 2012 Dec 28. Review.
Loncke F, Nijs M, Smet L SMOG: Spreken Met Ondersteuning van Gebaren [SMOG: Speaking With Support of Signs].4th ed. Antwerpen: Garant; 2012. 180 p. Dutch
Mayberry RI, Jaques J, DeDe G What stuttering reveals about the development of the gesture-speech relationship. New Dir Child Dev. 1998 Spring;(79):77-87.
Meuris K, Maes B, Zink I Evaluation of language and communication skills in adult key word signing users with intellectual disability: advantages of a narrative task. Res Dev Disabil. 2014 Oct;35(10):2585-601. doi: 10.1016/j.ridd.2014.06.020. Epub 2014 Jul 10.
Preus, A Treatment of mentally retarded stutterers. J Fluency Dis. 1990; 15(4):223-233.
Pruess JB, Vadasy PF, Fewell RR Language development in children with Down syndrome. Educ Train Ment Retard. 1987; 22(1): 44-55.
Roberts JE, Price J, Malkin C Language and communication development in Down syndrome. Ment Retard Dev Disabil Res Rev. 2007;13(1):26-35. Review.
Saltuklaroglu T, Kalinowski J The inhibition of stuttering via the perceptions and production of syllable repetitions. Int J Neurosci. 2011 Jan;121(1):44-9. doi: 10.3109/00207454.2011.536361.
Schaerlaekens A [Assessing and measuring language development in the child. The Reynell Scales in a Dutch language area]. Folia Phoniatr Logop. 1995;47(6):303-9. German.
Smith L, von Tetzchner S Communicative, sensorimotor, and language skills of young children with Down syndrome. Am J Ment Defic. 1986 Jul;91(1):57-66.
Snyder GJ, Waddell DE, Blanchet P Mirror neurons as a model for the science and treatment of stuttering. Neuroreport. 2016 Jan 6;27(1):56-60. doi: 10.1097/WNR.0000000000000500.
St Louis KO, Myers, FL. Clinical management of cluttering. Lang Speech Hear Serv Schools. 1995; 26(2): 187-195.
Velthuijs M Een taart voor kleine beer [A pie for little bear]. Rijswijk: De Vier Windstreken;1995. 27 p. Dutch
Willems RM, Hagoort P Neural evidence for the interplay between language, gesture, and action: a review. Brain Lang. 2007 Jun;101(3):278-89. Epub 2007 Apr 9. Review.
The Interaction Between Stuttering and Gestures and Their Influence on the Intelligibility of Individuals With Down Syndrome
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Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
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