NCT02750566 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Corps KN, Roth TL, McGavern DB
Inflammation and neuroprotection in traumatic brain injury. JAMA Neurol. 2015 Mar;72(3):355-62. doi: 10.1001/jamaneurol.2014.3558.
Fraix M, Gordon A, Graham V, Hurwitz E, Seffinger MA
Use of the SMART Balance Master to quantify the effects of osteopathic manipulative treatment in patients with dizziness. J Am Osteopath Assoc. 2013 May;113(5):394-403.
Guskiewicz KM, Register-Mihalik J, McCrory P, McCrea M, Johnston K, Makdissi M, Dvorak J, Davis G, Meeuwisse W
Evidence-based approach to revising the SCAT2: introducing the SCAT3. Br J Sports Med. 2013 Apr;47(5):289-93. doi: 10.1136/bjsports-2013-092225.
King D, Gissane C, Hume PA, Flaws M
The King-Devick test was useful in management of concussion in amateur rugby union and rugby league in New Zealand. J Neurol Sci. 2015 Apr 15;351(1-2):58-64. doi: 10.1016/j.jns.2015.02.035. Epub 2015 Feb 26.
Schatz P, Pardini JE, Lovell MR, Collins MW, Podell K
Sensitivity and specificity of the ImPACT Test Battery for concussion in athletes. Arch Clin Neuropsychol. 2006 Jan;21(1):91-9. doi: 10.1016/j.acn.2005.08.001. Epub 2005 Sep 6.

Comparing the Effect of Osteopathic Manipulative Medicine (OMM) Versus Counseling in the Treatment of Concussion

Clinical trial NCT02750566 - References