NCT01238276 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Champoux N, Du Souich P, Ravaoarinoro M, Phaneuf D, Latour J, Cusson JR
Single-dose pharmacokinetics of ampicillin and tobramycin administered by hypodermoclysis in young and older healthy volunteers. Br J Clin Pharmacol. 1996 Sep;42(3):325-31.
Frisoli Junior A, de Paula AP, Feldman D, Nasri F
Subcutaneous hydration by hypodermoclysis. A practical and low cost treatment for elderly patients. Drugs Aging. 2000 Apr;16(4):313-9. Review.
Lavery LA, Armstrong DG, Murdoch DP, Peters EJ, Lipsky BA
Validation of the Infectious Diseases Society of America's diabetic foot infection classification system. Clin Infect Dis. 2007 Feb 15;44(4):562-5. Epub 2007 Jan 17.
Weninger KR, Camara CG, Putterman SJ
Observation of bubble dynamics within luminescent cavitation clouds: Sonoluminescence at the nano-scale. Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Jan;63(1 Pt 2):016310. Epub 2000 Dec 27.

Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion

Clinical trial NCT01238276 - References