Clinical trial NCT06091163 - References

Depression — Ketogenic Diet for Treatment-Resistant Depression: Dietary Interventions for MEntal Health Study (DIME)

Citation(s)

•   Ali S, Rhodes L, Moreea O, McMillan D, Gilbody S, Leach C, Lucock M, Lutz W, Delgadillo J
  How durable is the effect of low intensity CBT for depression and anxiety? Remission and relapse in a longitudinal cohort study. Behav Res Ther. 2017 Jul;94:1-8. doi: 10.1016/j.brat.2017.04.006. Epub 2017 Apr 18.
•   Attaye I, van Oppenraaij S, Warmbrunn MV, Nieuwdorp M
  The Role of the Gut Microbiota on the Beneficial Effects of Ketogenic Diets. Nutrients. 2021 Dec 31;14(1):191. doi: 10.3390/nu14010191.
•   Bough KJ, Wetherington J, Hassel B, Pare JF, Gawryluk JW, Greene JG, Shaw R, Smith Y, Geiger JD, Dingledine RJ
  Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet. Ann Neurol. 2006 Aug;60(2):223-35. doi: 10.1002/ana.20899.
•   Brietzke E, Mansur RB, Subramaniapillai M, Balanza-Martinez V, Vinberg M, Gonzalez-Pinto A, Rosenblat JD, Ho R, McIntyre RS
  Ketogenic diet as a metabolic therapy for mood disorders: Evidence and developments. Neurosci Biobehav Rev. 2018 Nov;94:11-16. doi: 10.1016/j.neubiorev.2018.07.020. Epub 2018 Jul 31.
•   Chesney E, Goodwin GM, Fazel S
  Risks of all-cause and suicide mortality in mental disorders: a meta-review. World Psychiatry. 2014 Jun;13(2):153-60. doi: 10.1002/wps.20128.
•   Cuijpers P, Karyotaki E, Weitz E, Andersson G, Hollon SD, van Straten A
  The effects of psychotherapies for major depression in adults on remission, recovery and improvement: a meta-analysis. J Affect Disord. 2014 Apr;159:118-26. doi: 10.1016/j.jad.2014.02.026. Epub 2014 Feb 24.
•   Cummergen K, Hannah L, Jopling L, Cameron R, Walsh C, Perez J
  What outcomes matter to service users who experience persistent depression: A mixed-method narrative review and synthesis. Journal of Affective Disorders Reports 2022; 10: 100431.
•   Dietch DM, Kerr-Gaffney J, Hockey M, Marx W, Ruusunen A, Young AH, Berk M, Mondelli V
  Efficacy of low carbohydrate and ketogenic diets in treating mood and anxiety disorders: systematic review and implications for clinical practice. BJPsych Open. 2023 Apr 17;9(3):e70. doi: 10.1192/bjo.2023.36.
•   Duking T, Spieth L, Berghoff SA, Piepkorn L, Schmidke AM, Mitkovski M, Kannaiyan N, Hosang L, Scholz P, Shaib AH, Schneider LV, Hesse D, Ruhwedel T, Sun T, Linhoff L, Trevisiol A, Kohler S, Pastor AM, Misgeld T, Sereda M, Hassouna I, Rossner MJ, Odoardi F, Ischebeck T, de Hoz L, Hirrlinger J, Jahn O, Saher G
  Ketogenic diet uncovers differential metabolic plasticity of brain cells. Sci Adv. 2022 Sep 16;8(37):eabo7639. doi: 10.1126/sciadv.abo7639. Epub 2022 Sep 16.
•   Duman RS, Sanacora G, Krystal JH
  Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments. Neuron. 2019 Apr 3;102(1):75-90. doi: 10.1016/j.neuron.2019.03.013.
•   Ebbeling CB, Feldman HA, Klein GL, Wong JMW, Bielak L, Steltz SK, Luoto PK, Wolfe RR, Wong WW, Ludwig DS
  Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial. BMJ. 2018 Nov 14;363:k4583. doi: 10.1136/bmj.k4583. Erratum In: BMJ. 2020 Nov 3;371:m4264.
•   Fattal O, Budur K, Vaughan AJ, Franco K
  Review of the literature on major mental disorders in adult patients with mitochondrial diseases. Psychosomatics. 2006 Jan-Feb;47(1):1-7. doi: 10.1176/appi.psy.47.1.1.
•   Garcia-Rodriguez D, Gimenez-Cassina A
  Ketone Bodies in the Brain Beyond Fuel Metabolism: From Excitability to Gene Expression and Cell Signaling. Front Mol Neurosci. 2021 Aug 27;14:732120. doi: 10.3389/fnmol.2021.732120. eCollection 2021.
•   Guan YF, Huang GB, Xu MD, Gao F, Lin S, Huang J, Wang J, Li YQ, Wu CH, Yao S, Wang Y, Zhang YL, Teoh JP, Xuan A, Sun XD
  Anti-depression effects of ketogenic diet are mediated via the restoration of microglial activation and neuronal excitability in the lateral habenula. Brain Behav Immun. 2020 Aug;88:748-762. doi: 10.1016/j.bbi.2020.05.032. Epub 2020 May 12.
•   Guarnotta V, Emanuele F, Amodei R, Giordano C
  Very Low-Calorie Ketogenic Diet: A Potential Application in the Treatment of Hypercortisolism Comorbidities. Nutrients. 2022 Jun 9;14(12):2388. doi: 10.3390/nu14122388.
•   Hallbook T, Ji S, Maudsley S, Martin B
  The effects of the ketogenic diet on behavior and cognition. Epilepsy Res. 2012 Jul;100(3):304-9. doi: 10.1016/j.eplepsyres.2011.04.017. Epub 2011 Aug 27.
•   Jarrett SG, Milder JB, Liang LP, Patel M
  The ketogenic diet increases mitochondrial glutathione levels. J Neurochem. 2008 Aug;106(3):1044-51. doi: 10.1111/j.1471-4159.2008.05460.x. Epub 2008 May 5.
•   Johnson CF, Macdonald HJ, Atkinson P, Buchanan AI, Downes N, Dougall N
  Reviewing long-term antidepressants can reduce drug burden: a prospective observational cohort study. Br J Gen Pract. 2012 Nov;62(604):e773-9. doi: 10.3399/bjgp12X658304.
•   Karkkainen O, Farokhnia M, Klavus A, Auriola S, Lehtonen M, Deschaine SL, Piacentino D, Abshire KM, Jackson SN, Leggio L
  Effect of intravenous ghrelin administration, combined with alcohol, on circulating metabolome in heavy drinking individuals with alcohol use disorder. Alcohol Clin Exp Res. 2021 Nov;45(11):2207-2216. doi: 10.1111/acer.14719. Epub 2021 Sep 30.
•   Khan A, Brown WA
  Antidepressants versus placebo in major depression: an overview. World Psychiatry. 2015 Oct;14(3):294-300. doi: 10.1002/wps.20241.
•   Kroenke K, Spitzer RL, Williams JB
  The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13. doi: 10.1046/j.1525-1497.2001.016009606.x.
•   Lam RW, Lamy FX, Danchenko N, Yarlas A, White MK, Rive B, Saragoussi D
  Psychometric validation of the Perceived Deficits Questionnaire-Depression (PDQ-D) instrument in US and UK respondents with major depressive disorder. Neuropsychiatr Dis Treat. 2018 Oct 29;14:2861-2877. doi: 10.2147/NDT.S175188. eCollection 2018.
•   Lowe B, Unutzer J, Callahan CM, Perkins AJ, Kroenke K
  Monitoring depression treatment outcomes with the patient health questionnaire-9. Med Care. 2004 Dec;42(12):1194-201. doi: 10.1097/00005650-200412000-00006.
•   Martin K, Jackson CF, Levy RG, Cooper PN
  Ketogenic diet and other dietary treatments for epilepsy. Cochrane Database Syst Rev. 2016 Feb 9;2:CD001903. doi: 10.1002/14651858.CD001903.pub3.
•   Miletic S, Boag RJ, Trutti AC, Stevenson N, Forstmann BU, Heathcote A
  A new model of decision processing in instrumental learning tasks. Elife. 2021 Jan 27;10:e63055. doi: 10.7554/eLife.63055.
•   Mordor Intelligence LLC
  Global Ketogenic Diet Food Market - Growth, Trends and Forecast (2019 - 2024). 2019. https://www.reportlinker.com/p05790924/Global-Ketogenic-Diet-Food-Market-Growth-Trends-and-Forecast.html#:~:text=The%20global%20ketogenic%20diet%20food,and%20aiding%20in%20weight%2Dloss.
•   Mundt JC, Marks IM, Shear MK, Greist JH
  The Work and Social Adjustment Scale: a simple measure of impairment in functioning. Br J Psychiatry. 2002 May;180:461-4. doi: 10.1192/bjp.180.5.461.
•   Page CE, Coutellier L
  Prefrontal excitatory/inhibitory balance in stress and emotional disorders: Evidence for over-inhibition. Neurosci Biobehav Rev. 2019 Oct;105:39-51. doi: 10.1016/j.neubiorev.2019.07.024. Epub 2019 Aug 1.
•   Puchowicz MA, Xu K, Sun X, Ivy A, Emancipator D, LaManna JC
  Diet-induced ketosis increases capillary density without altered blood flow in rat brain. Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1607-15. doi: 10.1152/ajpendo.00512.2006. Epub 2007 Feb 6.
•   Schulz KF, Altman DG, Moher D; CONSORT Group
  CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. BMJ. 2010 Mar 23;340:c332. doi: 10.1136/bmj.c332.
•   Snaith RP, Hamilton M, Morley S, Humayan A, Hargreaves D, Trigwell P
  A scale for the assessment of hedonic tone the Snaith-Hamilton Pleasure Scale. Br J Psychiatry. 1995 Jul;167(1):99-103. doi: 10.1192/bjp.167.1.99.
•   Spitzer RL, Kroenke K, Williams JB, Lowe B
  A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092-7. doi: 10.1001/archinte.166.10.1092.
•   van Berkel AA, IJff DM, Verkuyl JM
  Cognitive benefits of the ketogenic diet in patients with epilepsy: A systematic overview. Epilepsy Behav. 2018 Oct;87:69-77. doi: 10.1016/j.yebeh.2018.06.004. Epub 2018 Aug 31.
•   Villa RF, Ferrari F, Bagini L, Gorini A, Brunello N, Tascedda F
  Mitochondrial energy metabolism of rat hippocampus after treatment with the antidepressants desipramine and fluoxetine. Neuropharmacology. 2017 Jul 15;121:30-38. doi: 10.1016/j.neuropharm.2017.04.025. Epub 2017 Apr 18.
•   Walsh AEL, Browning M, Drevets WC, Furey M, Harmer CJ
  Dissociable temporal effects of bupropion on behavioural measures of emotional and reward processing in depression. Philos Trans R Soc Lond B Biol Sci. 2018 Mar 19;373(1742):20170030. doi: 10.1098/rstb.2017.0030.
•   Ware J Jr, Kosinski M, Keller SD
  A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996 Mar;34(3):220-33. doi: 10.1097/00005650-199603000-00003.
•   Yarar-Fisher C, Li J, Womack ED, Alharbi A, Seira O, Kolehmainen KL, Plunet WT, Alaeiilkhchi N, Tetzlaff W
  Ketogenic regimens for acute neurotraumatic events. Curr Opin Biotechnol. 2021 Aug;70:68-74. doi: 10.1016/j.copbio.2020.12.009. Epub 2021 Jan 11.
•   Yudkoff M, Daikhin Y, Nissim I, Horyn O, Lazarow A, Luhovyy B, Wehrli S, Nissim I
  Response of brain amino acid metabolism to ketosis. Neurochem Int. 2005 Jul;47(1-2):119-28. doi: 10.1016/j.neuint.2005.04.014.
•   Zarnowski T, Choragiewicz T, Tulidowicz-Bielak M, Thaler S, Rejdak R, Zarnowski I, Turski WA, Gasior M
  Ketogenic diet increases concentrations of kynurenic acid in discrete brain structures of young and adult rats. J Neural Transm (Vienna). 2012 Jun;119(6):679-84. doi: 10.1007/s00702-011-0750-2. Epub 2011 Dec 27.

A Randomised Controlled Trial Evaluating the Efficacy and Mechanisms of a Ketogenic Diet as an Adjunctive Treatment for People With Treatment-resistant Depression

Details for clinical trial NCT06091163