Depression — Addressing Depression and Positive Parenting Techniques (ADAPT)
Citation(s)
Aitken M, Waxman JA, MacDonald K, Andrade BF Effect of Comorbid Psychopathology and Conduct Problem Severity on Response to a Multi-component Intervention for Childhood Disruptive Behavior. Child Psychiatry Hum Dev. 2018 Dec;49(6):853-864. doi: 10.1007/s10578-018-0800-1.
Eyberg, S M., et al. Manual for the dyadic parent-child interaction coding system: Third edition. 2009, University of Florida.
Fanti, KA, Panaylotou G, and Fanti S Associating parental to child psychological symptoms: Investigating a transactional model of development. Journal of Emotional and Behavioral Disorders 21(3): 193-210, 2013.
Harvey P, Penzo JA Parenting a child who has intense emotions: Dialectical behavior therapy skills to help your child regulate emotional outbursts & aggressive behaviors. Oakland, CA: New Harbinger Publications, 2009.
Ludmer JA, Salsbury D, Suarez J, Andrade BF Accounting for the impact of parent internalizing symptoms on Parent Training benefits: The role of positive parenting. Behav Res Ther. 2017 Oct;97:252-258. doi: 10.1016/j.brat.2017.08.012. Epub 2017 Aug 23.
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Peris TS, Hinshaw SP Family dynamics and preadolescent girls with ADHD: the relationship between expressed emotion, ADHD symptomatology, and comorbid disruptive behavior. J Child Psychol Psychiatry. 2003 Nov;44(8):1177-90. doi: 10.1111/1469-7610.00199.
Optimizing Treatment for Parents of Children With Emotional and Behavioural Problems (OPTED)
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.