NCT02686632 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Cross LJ, Williams DW, Sweeney CP, Jackson MS, Lewis MA, Bagg J
Evaluation of the recurrence of denture stomatitis and Candida colonization in a small group of patients who received itraconazole. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Mar;97(3):351-8.
de Oliveira CE, Gasparoto TH, Dionísio TJ, Porto VC, Vieira NA, Santos CF, Lara VS
Candida albicans and denture stomatitis: evaluation of its presence in the lesion, prosthesis, and blood. Int J Prosthodont. 2010 Mar-Apr;23(2):158-9.
Emami E, de Grandmont P, Rompré PH, Barbeau J, Pan S, Feine JS
Favoring trauma as an etiological factor in denture stomatitis. J Dent Res. 2008 May;87(5):440-4.
Gendreau L, Loewy ZG
Epidemiology and etiology of denture stomatitis. J Prosthodont. 2011 Jun;20(4):251-60. doi: 10.1111/j.1532-849X.2011.00698.x. Epub 2011 Apr 4. Review.
Jainkittivong A, Aneksuk V, Langlais RP
Oral mucosal lesions in denture wearers. Gerodontology. 2010 Mar;27(1):26-32.
Slade GD, Akinkugbe AA, Sanders AE
Projections of U.S. Edentulism prevalence following 5 decades of decline. J Dent Res. 2014 Oct;93(10):959-65. doi: 10.1177/0022034514546165. Epub 2014 Aug 21.

Improving Practice Guidelines for the Treatment of Denture-related Erythematous Stomatitis: A Pragmatic International Multicenter Randomized Controlled Trial

Details for clinical trial NCT02686632

Clinical trial NCT02686632 - References