NCT04896294 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Makeeva IM, Budaychieva ZS, Polyakova MA, Margaryan EG, Novozhilova NE, Musiyev AA
[Special aspects of individual oral hygiene in patients with I class gingival recession]. Stomatologiia (Mosk). 2019;98(4):25-28. doi: 10.17116/stomat20199804125. Russian.
Makeeva IM, Polyakova MA, Doroshina VY, Sokhova IA, Arakelyan MG, Makeeva MK
[Efficiency of paste and suspension with nano-hydroxyapatite on the sensitivity of teeth with gingival recession]. Stomatologiia (Mosk). 2018;97(4):23-27. doi: 10.17116/stomat20189704123. Russian.
Makeeva IM, Polyakova MA, Doroshina VY, Turkina AY, Babina KS, Arakelyan MG
[Comparative effectiveness of therapeutic toothpastes with fluoride and hydroxyapatite]. Stomatologiia (Mosk). 2018;97(5):34-40. doi: 10.17116/stomat20189705134. Russian.
Polyakova MA, Arakelyan MG, Babina KS, Margaryan EG, Sokhova IA, Doroshina VY, Novozhilova NE
Qualitative and Quantitative Assessment of Remineralizing Effect of Prophylactic Toothpaste Promoting Brushite Formation: A Randomized Clinical Trial. J Int Soc Prev Community Dent. 2020 May 7;10(3):359-367. doi: 10.4103/jispcd.JISPCD_493_19. eCollection 2020 May-Jun.
Sokhova IA, Doroshina VY, Polyakova MA, Margaryan EG
[Comparative assessment of the effectiveness of toothpastes to reduce hyperesthesia in inflammatory periodontal diseases]. Stomatologiia (Mosk). 2020;99(1):27-32. doi: 10.17116/stomat20209901127. Russian.

The Effect of Toothpastes Containing Ca-hydroxyapatite, Fluoroapatite, and Mg-Zn-hydroxyapatite on Dentin Hypersensitivity: a Randomized Clinical Trial

Details for clinical trial NCT04896294

Clinical trial NCT04896294 - References