NCT02460562 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Kamijo K, Mukai Y, Tominaga T, Iwaya I, Fujino F, Hirata Y, Teranaka T
Fluoride release and recharge characteristics of denture base resins containing surface pre-reacted glass-ionomer filler. Dent Mater J. 2009 Mar;28(2):227-33.
Ma S, Imazato S, Chen JH, Mayanagi G, Takahashi N, Ishimoto T, Nakano T
Effects of a coating resin containing S-PRG filler to prevent demineralization of root surfaces. Dent Mater J. 2012;31(6):909-15.
Mukai Y, Kamijo K, Fujino F, Hirata Y, Teranaka T, ten Cate JM
Effect of denture base-resin with prereacted glass-ionomer filler on dentin demineralization. Eur J Oral Sci. 2009 Dec;117(6):750-4. doi: 10.1111/j.1600-0722.2009.00678.x.

The Caries Prevention Effect of Surface Pre-reacted Glass-ionomer Filler Incorporated in Denture Base Resins on Edentulous Elderly People

Clinical trial NCT02460562 - References