Dental Caries — Postoperative Hypersensitivity Randomized Comparative Effectiveness Research Trial
Citation(s)
Akpata ES, Behbehani J Effect of bonding systems on post-operative sensitivity from posterior composites. Am J Dent. 2006 Jun;19(3):151-4.
Akpata ES, Sadiq W Post-operative sensitivity in glass-ionomer versus adhesive resin-lined posterior composites. Am J Dent. 2001 Feb;14(1):34-8.
American Academy of Sleep Medicine (2001) The international classification of sleep disorders, revised: diagnosis and coding manual. Westchester, IL: American Academy of Sleep Medicine.
Casselli DS, Martins LR Postoperative sensitivity in Class I composite resin restorations in vivo. J Adhes Dent. 2006 Feb;8(1):53-8.
Cho BH, Dickens SH, Bae JH, Chang CG, Son HH, Um CM Effect of interfacial bond quality on the direction of polymerization shrinkage flow in resin composite restorations. Oper Dent. 2002 May-Jun;27(3):297-304.
Christensen GJ Preventing postoperative tooth sensitivity in class I, II and V restorations. J Am Dent Assoc. 2002 Feb;133(2):229-31.
Efes BG, Dörter C, Gömeç Y, Koray F Two-year clinical evaluation of ormocer and nanofill composite with and without a flowable liner. J Adhes Dent. 2006 Apr;8(2):119-26.
Gordan VV, Mjör IA Short- and long-term clinical evaluation of post-operative sensitivity of a new resin-based restorative material and self-etching primer. Oper Dent. 2002 Nov-Dec;27(6):543-8.
Hayashi M, Wilson NH Failure risk of posterior composites with post-operative sensitivity. Oper Dent. 2003 Nov-Dec;28(6):681-8.
Kaurani M, Bhagwat SV Clinical evaluation of postoperative sensitivity in composite resin restorations using various liners. N Y State Dent J. 2007 Mar;73(2):23-9.
Lavigne GJ, Manzini C, Kato T (2005) Sleep Bruxism. In: Principles and practice of sleep medicine. MH Kryger, T Roth and WC Dement editors. Philadelphia: Elsevier, pp. 946-59
Letzel H Survival rates and reasons for failure of posterior composite restorations in multicentre clinical trial. J Dent. 1989;17 Suppl 1:S10-7; discussion S26-8.
Liang K-Y, Zeger SL (1986) Longitudinal data analysis using generalized linear models. Biometrika 73:13-22.
Lundin SA, Rasmusson CG Clinical evaluation of a resin composite and bonding agent in Class I and II restorations: 2-year results. Quintessence Int. 2004 Oct;35(9):758-62.
Opdam NJ, Feilzer AJ, Roeters JJ, Smale I Class I occlusal composite resin restorations: in vivo post-operative sensitivity, wall adaptation, and microleakage. Am J Dent. 1998 Oct;11(5):229-34.
Sadeghi M, Lynch CD, Shahamat N Eighteen-month clinical evaluation of microhybrid, packable and nanofilled resin composites in Class I restorations. J Oral Rehabil. 2010 Jul;37(7):532-7. doi: 10.1111/j.1365-2842.2010.02073.x. Epub 2010 Feb 25.
Türkün LS, Türkün M, Ozata F Clinical performance of a packable resin composite for a period of 3 years. Quintessence Int. 2005 May;36(5):365-72.
van Dijken JW, Sunnegårdh-Grönberg K A two-year clinical evaluation of a new calcium aluminate cement in Class II cavities. Acta Odontol Scand. 2003 Aug;61(4):235-40.
Wilson NH, Wilson MA, Smith GA A clinical trial of a new visible light-cured composite restorative-- initial findings and one-year results. Quintessence Int. 1985 Apr;16(4):281-90.
Yip KH, Poon BK, Chu FC, Poon EC, Kong FY, Smales RJ Clinical evaluation of packable and conventional hybrid resin-based composites for posterior restorations in permanent teeth: results at 12 months. J Am Dent Assoc. 2003 Dec;134(12):1581-9.
Resin Based Composite Occlusal Restoration Postoperative Hypersensitivity: Randomized Comparative Effectiveness Research Trial
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.