Dental Anxiety — Virtual Reality Distraction for Dental Anxiety (RCT)
Citation(s)
Al-Khotani A, Bello LA, Christidis N Effects of audiovisual distraction on children's behaviour during dental treatment: a randomized controlled clinical trial. Acta Odontol Scand. 2016 Aug;74(6):494-501. doi: 10.1080/00016357.2016.1206211. Epub 2016 Jul 13.
Alaki SM, Safi A, Ouda S, Nadhreen A Comparing Dental Stress in New Child Patients and Returning Patients Using Salivary Cortisol, Immunoglobulin-A and Alpha- Amylase. J Clin Pediatr Dent. 2017;41(6):462-466. doi: 10.17796/1053-4628-41.6.8. Epub 2017 Sep 22.
AlMaummar M, AlThabit HO, Pani S The impact of dental treatment and age on salivary cortisol and alpha-amylase levels of patients with varying degrees of dental anxiety. BMC Oral Health. 2019 Sep 6;19(1):211. doi: 10.1186/s12903-019-0901-7.
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Cunningham A, McPolin O, Fallis R, Coyle C, Best P, McKenna G A systematic review of the use of virtual reality or dental smartphone applications as interventions for management of paediatric dental anxiety. BMC Oral Health. 2021 May 7;21(1):244. doi: 10.1186/s12903-021-01602-3.
Efird J Blocked randomization with randomly selected block sizes. Int J Environ Res Public Health. 2011 Jan;8(1):15-20. doi: 10.3390/ijerph8010015. Epub 2010 Dec 23.
Furlan NF, Gaviao MB, Barbosa TS, Nicolau J, Castelo PM Salivary cortisol, alpha-amylase and heart rate variation in response to dental treatment in children. J Clin Pediatr Dent. 2012 Fall;37(1):83-7. doi: 10.17796/jcpd.37.1.n32m21n08417v363.
Humphris G, King K The prevalence of dental anxiety across previous distressing experiences. J Anxiety Disord. 2011 Mar;25(2):232-6. doi: 10.1016/j.janxdis.2010.09.007. Epub 2010 Sep 19.
Koneru A, Sigal MJ Access to dental care for persons with developmental disabilities in Ontario. J Can Dent Assoc. 2009 Mar;75(2):121.
Luoto A, Lahti S, Nevanpera T, Tolvanen M, Locker D Oral-health-related quality of life among children with and without dental fear. Int J Paediatr Dent. 2009 Mar;19(2):115-20. doi: 10.1111/j.1365-263X.2008.00943.x.
Murad MH, Ingle NA, Assery MK Evaluating factors associated with fear and anxiety to dental treatment-A systematic review. J Family Med Prim Care. 2020 Sep 30;9(9):4530-4535. doi: 10.4103/jfmpc.jfmpc_607_20. eCollection 2020 Sep.
Nunna M, Dasaraju RK, Kamatham R, Mallineni SK, Nuvvula S Comparative evaluation of virtual reality distraction and counter-stimulation on dental anxiety and pain perception in children. J Dent Anesth Pain Med. 2019 Oct;19(5):277-288. doi: 10.17245/jdapm.2019.19.5.277. Epub 2019 Oct 30.
Oliveira MA, Vale MP, Bendo CB, Paiva SM, Serra-Negra JM Influence of negative dental experiences in childhood on the development of dental fear in adulthood: a case-control study. J Oral Rehabil. 2017 Jun;44(6):434-441. doi: 10.1111/joor.12513. Epub 2017 May 3.
Sahebalam R, Rafieinezhad R, Boskabad M Comparison of the Efficacy of Jilo Animation Approach versus Conventional Tell-Show-Do (TSD) Technique on Cooperation and Anxiety Levels of Children during Dental Practice: A Randomized Controlled Clinical Trials. J Dent (Shiraz). 2020 Dec;21(4):284-291. doi: 10.30476/dentjods.2020.81897.1001.
Shim YS, Kim AH, Jeon EY, An SY Dental fear & anxiety and dental pain in children and adolescents; a systemic review. J Dent Anesth Pain Med. 2015 Jun;15(2):53-61. doi: 10.17245/jdapm.2015.15.2.53. Epub 2015 Jun 30.
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Venham LL The effect of mother's presence of child's response to dental treatment. ASDC J Dent Child. 1979 May-Jun;46(3):219-25. No abstract available.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
