NCT03348800 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Garret-Bernardin A, Cantile T, D'Antò V, Galanakis A, Fauxpoint G, Ferrazzano GF, De Rosa S, Vallogini G, Romeo U, Galeotti A
Pain Experience and Behavior Management in Pediatric Dentistry: A Comparison between Traditional Local Anesthesia and the Wand Computerized Delivery System. Pain Res Manag. 2017;2017:7941238. doi: 10.1155/2017/7941238. Epub 2017 Feb 15.
Patini R, Coviello V, Raffaelli L, Manicone PF, Dehkhargani SZ, Verdugo F, Perfetti G, D'Addona A
Subjective pain response to two anesthetic systems in dental surgery: traditional syringe vs. a computer controlled delivery system. J Biol Regul Homeost Ag

Anesthesia in Pediatric Dental Surgery: Effects of a Computer Controlled Delivery System on Pain and Heart Rate. A Randomized Clinical Trial

Clinical trial NCT03348800 - References