Dementia — Care of Older People With Cognitive Impairment or Dementia Hospitalized in Traumatology Units
Citation(s)
Abellán A, Pujol R Un perfil de las personas mayores en España. Indicadores estadísticos básicos. 2016. Consejo Superior de Investigaciones Científicas (CSIC). Centro de Ciencias Humanas y Sociales (CCHS). Envejecimiento en red.
Charlson ME, Pompei P, Ales KL, MacKenzie CR A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373-83.
Librero J, Peiró S, Ordiñana R Chronic comorbidity and outcomes of hospital care: length of stay, mortality, and readmission at 30 and 365 days. J Clin Epidemiol. 1999 Mar;52(3):171-9.
Risco E, Zabalegui A, Miguel S, Farré M, Alvira C, Cabrera E [Application of the Balance of Care model in decision-making regarding the best care for patients with dementia]. Gac Sanit. 2017 Nov - Dec;31(6):518-523. doi: 10.1016/j.gaceta.2016.07.006. Epub 2016 Oct 15. Spanish.
Warden V, Hurley AC, Volicer L Development and psychometric evaluation of the Pain Assessment in Advanced Dementia (PAINAD) scale. J Am Med Dir Assoc. 2003 Jan-Feb;4(1):9-15.
Wimo A, Wetterholm AL, Mastey V, Winblad B Evaluation of the resource utilization and caregiver time in Anti-dementia drug trials - a quantitative battery. in: Wimo A, Karlsson G, Jönsson B, Winblad B (eds) . The Health Economics of Dementia, 1998. Wiley's, London, UK
Care of Older People With Cognitive Impairment or Dementia Hospitalized in Traumatology Units
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
