NCT00071903 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Calabrese VP, Selhorst JB, Harbison JW
CSF infusion test in pseudotumor cerebri. Trans Am Neurol Assoc. 1978;103:146-50.
Martins AN
Resistance to drainage of cerebrospinal fluid: clinical measurement and significance. J Neurol Neurosurg Psychiatry. 1973 Apr;36(2):313-8.
Quattrone A, Gambardella A, Carbone AM, Oliveri RL, Lavano A, De Marco EV, Civitelli D, Bono F, Zappia M, Pardatscher K, DiMinno G
A hypofibrinolytic state in overweight patients with cerebral venous thrombosis and isolated intracranial hypertension. J Neurol. 1999 Nov;246(11):1086-9.

The Role of Susceptibility to Thrombosis in the Pseudotumor Cerebri of Nephropathic Cystinosis: A Case-Control Study

Clinical trial NCT00071903 - References