Amrein K, Ribitsch W, Otto R, Worm HC, Stauber RE Severe lactic acidosis reversed by thiamine within 24 hours. Crit Care. 2011;15(6):457. doi: 10.1186/cc10495. Epub 2011 Dec 1. No abstract available.
Andersen LW, Liu X, Peng TJ, Giberson TA, Khabbaz KR, Donnino MW Pyruvate Dehydrogenase Activity and Quantity Decreases After Coronary Artery Bypass Grafting: a Prospective Observational Study. Shock. 2015 Mar;43(3):250-4. doi: 10.1097/SHK.0000000000000306.
Atkinson TM, Konold TR, Glutting JJ Patterns of memory: a normative taxonomy of the Wide Range Assessment of Memory and Learning-Second Edition (WRAML-2). J Int Neuropsychol Soc. 2008 Sep;14(5):869-77. doi: 10.1017/S1355617708081137.
Attaluri P, Castillo A, Edriss H, Nugent K Thiamine Deficiency: An Important Consideration in Critically Ill Patients. Am J Med Sci. 2018 Oct;356(4):382-390. doi: 10.1016/j.amjms.2018.06.015. Epub 2018 Jun 21.
Ba A Metabolic and structural role of thiamine in nervous tissues. Cell Mol Neurobiol. 2008 Nov;28(7):923-31. doi: 10.1007/s10571-008-9297-7. Epub 2008 Jul 19.
Barnett SD, Ad N Surgery for aortic and mitral valve disease in the United States: a trend of change in surgical practice between 1998 and 2005. J Thorac Cardiovasc Surg. 2009 Jun;137(6):1422-9. doi: 10.1016/j.jtcvs.2008.08.071. Epub 2009 Feb 20.
Bautista-Hernandez VM, Lopez-Ascencio R, Del Toro-Equihua M, Vasquez C Effect of thiamine pyrophosphate on levels of serum lactate, maximum oxygen consumption and heart rate in athletes performing aerobic activity. J Int Med Res. 2008 Nov-Dec;36(6):1220-6. doi: 10.1177/147323000803600608.
Bolszak S, Casartelli NC, Impellizzeri FM, Maffiuletti NA Validity and reproducibility of the Physical Activity Scale for the Elderly (PASE) questionnaire for the measurement of the physical activity level in patients after total knee arthroplasty. BMC Musculoskelet Disord. 2014 Feb 20;15:46. doi: 10.1186/1471-2474-15-46.
Brady JA, Rock CL, Horneffer MR Thiamin status, diuretic medications, and the management of congestive heart failure. J Am Diet Assoc. 1995 May;95(5):541-4. doi: 10.1016/S0002-8223(95)00148-4.
Bursa F, Pleva L Anaerobic metabolism associated with traumatic hemorrhagic shock monitored by microdialysis of muscle tissue is dependent on the levels of hemoglobin and central venous oxygen saturation: a prospective, observational study. Scand J Trauma Resusc Emerg Med. 2014 Feb 5;22:11. doi: 10.1186/1757-7241-22-11.
Butterworth RF Effects of thiamine deficiency on brain metabolism: implications for the pathogenesis of the Wernicke-Korsakoff syndrome. Alcohol Alcohol. 1989;24(4):271-9. doi: 10.1093/oxfordjournals.alcalc.a044913.
Campbell CH Lacticacidosis and thiamine deficiency. Lancet. 1984 Dec 1;2(8414):1282. doi: 10.1016/s0140-6736(84)92835-6. No abstract available.
Chatzinikolaou A, Tzikas S, Lavdaniti M Assessment of Quality of Life in Patients With Cardiovascular Disease Using the SF-36, MacNew, and EQ-5D-5L Questionnaires. Cureus. 2021 Sep 14;13(9):e17982. doi: 10.7759/cureus.17982. eCollection 2021 Sep.
Cook CC Prevention and treatment of Wernicke-Korsakoff syndrome. Alcohol Alcohol Suppl. 2000 May-Jun;35(1):19-20. doi: 10.1093/alcalc/35.supplement_1.19.
Costantini A, Pala MI Thiamine and fatigue in inflammatory bowel diseases: an open-label pilot study. J Altern Complement Med. 2013 Aug;19(8):704-8. doi: 10.1089/acm.2011.0840. Epub 2013 Feb 4.
Crook MA Chapter 6 - Methods for assessment of Thiamine (Vitamin B1). In: Harrington D, ed. Laboratory Assessment of Vitamin Status. Academic Press; 2019:149-64.
Demers P, Elkouri S, Martineau R, Couturier A, Cartier R Outcome with high blood lactate levels during cardiopulmonary bypass in adult cardiac operation. Ann Thorac Surg. 2000 Dec;70(6):2082-6. doi: 10.1016/s0003-4975(00)02160-3.
DiNicolantonio JJ, Liu J, O'Keefe JH Thiamine and Cardiovascular Disease: A Literature Review. Prog Cardiovasc Dis. 2018 May-Jun;61(1):27-32. doi: 10.1016/j.pcad.2018.01.009. Epub 2018 Jan 31.
El-Ansary A, Bhat RS, Al-Daihan S, Al Dbass AM The neurotoxic effects of ampicillin-associated gut bacterial imbalances compared to those of orally administered propionic acid in the etiology of persistent autistic features in rat pups: effects of various dietary regimens. Gut Pathog. 2015 Mar 22;7:7. doi: 10.1186/s13099-015-0054-4. eCollection 2015.
Evered LA, Silbert BS, Scott DA, Maruff P, Ames D Prevalence of Dementia 7.5 Years after Coronary Artery Bypass Graft Surgery. Anesthesiology. 2016 Jul;125(1):62-71. doi: 10.1097/ALN.0000000000001143.
Faul F, Erdfelder E, Lang AG, Buchner A G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007 May;39(2):175-91. doi: 10.3758/bf03193146.
Gil L, Ruiz de Sanchez C, Gil F, Romero SJ, Pretelt Burgos F Validation of the Montreal Cognitive Assessment (MoCA) in Spanish as a screening tool for mild cognitive impairment and mild dementia in patients over 65 years old in Bogota, Colombia. Int J Geriatr Psychiatry. 2015 Jun;30(6):655-62. doi: 10.1002/gps.4199. Epub 2014 Oct 16.
Hung SC, Hung SH, Tarng DC, Yang WC, Chen TW, Huang TP Thiamine deficiency and unexplained encephalopathy in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis. 2001 Nov;38(5):941-7. doi: 10.1053/ajkd.2001.28578.
Inaguma D, Koide S, Takahashi K, Hayashi H, Hasegawa M, Yuzawa Y Relationship between history of coronary heart disease at dialysis initiation and onset of events associated with heart disease: a propensity-matched analysis of a prospective cohort study. BMC Nephrol. 2017 Feb 28;18(1):79. doi: 10.1186/s12882-017-0495-8.
Jain A, Mehta R, Al-Ani M, Hill JA, Winchester DE Determining the Role of Thiamine Deficiency in Systolic Heart Failure: A Meta-Analysis and Systematic Review. J Card Fail. 2015 Dec;21(12):1000-7. doi: 10.1016/j.cardfail.2015.10.005. Epub 2015 Oct 20.
Keogh AM, McNeil KD, Wlodarczyk J, Gabbay E, Williams TJ Quality of life in pulmonary arterial hypertension: improvement and maintenance with bosentan. J Heart Lung Transplant. 2007 Feb;26(2):181-7. doi: 10.1016/j.healun.2006.11.009.
Kumar R, Delshad S, Macey PM, Woo MA, Harper RM Development of T2-relaxation values in regional brain sites during adolescence. Magn Reson Imaging. 2011 Feb;29(2):185-93. doi: 10.1016/j.mri.2010.08.006. Epub 2010 Oct 8.
Latt N, Dore G Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders. Intern Med J. 2014 Sep;44(9):911-5. doi: 10.1111/imj.12522.
Lee IM, Sesso HD, Paffenbarger RS Jr Physical activity and coronary heart disease risk in men: does the duration of exercise episodes predict risk? Circulation. 2000 Aug 29;102(9):981-6. doi: 10.1161/01.cir.102.9.981.
Lee TA, Wolozin B, Weiss KB, Bednar MM Assessment of the emergence of Alzheimer's disease following coronary artery bypass graft surgery or percutaneous transluminal coronary angioplasty. J Alzheimers Dis. 2005 Aug;7(4):319-24. doi: 10.3233/jad-2005-7408.
Leslie DL, Inouye SK The importance of delirium: economic and societal costs. J Am Geriatr Soc. 2011 Nov;59 Suppl 2(Suppl 2):S241-3. doi: 10.1111/j.1532-5415.2011.03671.x.
Levy WC, Soine LA, Huth MM, Fishbein DP Thiamine deficiency in congestive heart failure. Am J Med. 1992 Dec;93(6):705-6. doi: 10.1016/0002-9343(92)90212-t. No abstract available.
Li J, Wynn RM, Machius M, Chuang JL, Karthikeyan S, Tomchick DR, Chuang DT Cross-talk between thiamin diphosphate binding and phosphorylation loop conformation in human branched-chain alpha-keto acid decarboxylase/dehydrogenase. J Biol Chem. 2004 Jul 30;279(31):32968-78. doi: 10.1074/jbc.M403611200. Epub 2004 May 27.
Li Q, Chen Q, Zhang H, Xu Z, Wang X, Pang J, Ma J, Ling W, Li D Associations of serum magnesium levels and calcium-magnesium ratios with mortality in patients with coronary artery disease. Diabetes Metab. 2020 Oct;46(5):384-391. doi: 10.1016/j.diabet.2019.12.003. Epub 2019 Dec 20.
Lindsay AJ, Xu M, Sessler DI, Blackstone EH, Bashour CA Lactate clearance time and concentration linked to morbidity and death in cardiac surgical patients. Ann Thorac Surg. 2013 Feb;95(2):486-92. doi: 10.1016/j.athoracsur.2012.07.020. Epub 2012 Sep 7.
Liu J, Wu JQ, Yang JJ, Wei JY, Gao WN, Guo CJ Metabolomic study on vitamins B(1), B(2), and PP supplementation to improve serum metabolic profiles in mice under acute hypoxia based on (1)H NMR analysis. Biomed Environ Sci. 2010 Aug;23(4):312-8. doi: 10.1016/S0895-3988(10)60069-4.
Morris G, Maes M Oxidative and Nitrosative Stress and Immune-Inflammatory Pathways in Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS). Curr Neuropharmacol. 2014 Mar;12(2):168-85. doi: 10.2174/1570159X11666131120224653.
Muller-Nordhorn J, Roll S, Willich SN Comparison of the short form (SF)-12 health status instrument with the SF-36 in patients with coronary heart disease. Heart. 2004 May;90(5):523-7. doi: 10.1136/hrt.2003.013995.
Myers J, Ashley E Dangerous curves. A perspective on exercise, lactate, and the anaerobic threshold. Chest. 1997 Mar;111(3):787-95. doi: 10.1378/chest.111.3.787.
Nardin M, Verdoia M, Negro F, Rolla R, Tonon F, De Luca G Impact of active smoking on the immature platelet fraction and its relationship with the extent of coronary artery disease. Eur J Clin Invest. 2020 Feb;50(2):e13181. doi: 10.1111/eci.13181. Epub 2020 Jan 18.
Nishimoto A, Usery J, Winton JC, Twilla J High-dose Parenteral Thiamine in Treatment of Wernicke's Encephalopathy: Case Series and Review of the Literature. In Vivo. 2017 Jan 2;31(1):121-124. doi: 10.21873/invivo.11034.
Paffenbarger RS Jr, Wing AL, Hyde RT Physical activity as an index of heart attack risk in college alumni. Am J Epidemiol. 1978 Sep;108(3):161-75. doi: 10.1093/oxfordjournals.aje.a112608.
Page GL, Laight D, Cummings MH Thiamine deficiency in diabetes mellitus and the impact of thiamine replacement on glucose metabolism and vascular disease. Int J Clin Pract. 2011 Jun;65(6):684-90. doi: 10.1111/j.1742-1241.2011.02680.x.
Pekovich SR, Martin PR, Singleton CK Thiamine deficiency decreases steady-state transketolase and pyruvate dehydrogenase but not alpha-ketoglutarate dehydrogenase mRNA levels in three human cell types. J Nutr. 1998 Apr;128(4):683-7. doi: 10.1093/jn/128.4.683. Erratum In: J Nutr 1998 Jul;128(7):1247.
Pike NA, Poulsen MK, Woo MA Validity of the Montreal Cognitive Assessment Screener in Adolescents and Young Adults With and Without Congenital Heart Disease. Nurs Res. 2017 May/Jun;66(3):222-230. doi: 10.1097/NNR.0000000000000192.
Pike NA, Roy B, Gupta R, Singh S, Woo MA, Halnon NJ, Lewis AB, Kumar R Brain abnormalities in cognition, anxiety, and depression regulatory regions in adolescents with single ventricle heart disease. J Neurosci Res. 2018 Jun;96(6):1104-1118. doi: 10.1002/jnr.24215. Epub 2018 Jan 6.
Schulz KF, Grimes DA Unequal group sizes in randomised trials: guarding against guessing. Lancet. 2002 Mar 16;359(9310):966-70. doi: 10.1016/S0140-6736(02)08029-7.
Sesso HD, Paffenbarger RS Jr, Lee IM Physical activity and coronary heart disease in men: The Harvard Alumni Health Study. Circulation. 2000 Aug 29;102(9):975-80. doi: 10.1161/01.cir.102.9.975.
Sheslow DA, W . Wide range assessment of memory and learning (2nd edition) administration and technical manual In: Editor, ed.^eds. Wide range assessment of memory and learning (2nd edition) administration and technical manual. City: Psychological Assessment Resources, 2003.
Singh S, Roy B, Halnon NJ, Lewis AB, Woo MA, Pike NA, Kumar R Regional brain changes in autonomic, mood, and cognitive control areas in adolescents with single ventricle heart disease. International Society for Magnetic Resonance in Medicine Annual Meeting, Paris, France, June 16-21, 2018: 2018.
Smith T, Gildeh N, Holmes C The Montreal Cognitive Assessment: validity and utility in a memory clinic setting. Can J Psychiatry. 2007 May;52(5):329-32. doi: 10.1177/070674370705200508.
Sriram K, Manzanares W, Joseph K Thiamine in nutrition therapy. Nutr Clin Pract. 2012 Feb;27(1):41-50. doi: 10.1177/0884533611426149. Epub 2012 Jan 4.
Sullivan EV, Fama R Wernicke's encephalopathy and Korsakoff's syndrome revisited. Neuropsychol Rev. 2012 Jun;22(2):69-71. doi: 10.1007/s11065-012-9205-2. Epub 2012 May 16. No abstract available.
Suter PM, Vetter W Diuretics and vitamin B1: are diuretics a risk factor for thiamin malnutrition? Nutr Rev. 2000 Oct;58(10):319-23. doi: 10.1111/j.1753-4887.2000.tb01827.x.
Thomson AD, Cook CC, Touquet R, Henry JA; Royal College of Physicians, London The Royal College of Physicians report on alcohol: guidelines for managing Wernicke's encephalopathy in the accident and Emergency Department. Alcohol Alcohol. 2002 Nov-Dec;37(6):513-21. doi: 10.1093/alcalc/37.6.513. Erratum In: Alcohol Alcohol. 2003 May-Jun;38(3):291.
Thomson AD, Cook CC Parenteral thiamine and Wernicke's encephalopathy: the balance of risks and perception of concern. Alcohol Alcohol. 1997 May-Jun;32(3):207-9. doi: 10.1093/oxfordjournals.alcalc.a008259.
Thornton EW, Groom C, Fabri BM, Fox MA, Hallas C, Jackson M Quality of life outcomes after coronary artery bypass graft surgery: relationship to neuropsychologic deficit. J Thorac Cardiovasc Surg. 2005 Oct;130(4):1022-7. doi: 10.1016/j.jtcvs.2005.05.020.
Tsai JC, Chen CW, Chu H, Yang HL, Chung MH, Liao YM, Chou KR Comparing the Sensitivity, Specificity, and Predictive Values of the Montreal Cognitive Assessment and Mini-Mental State Examination When Screening People for Mild Cognitive Impairment and Dementia in Chinese Population. Arch Psychiatr Nurs. 2016 Aug;30(4):486-91. doi: 10.1016/j.apnu.2016.01.015. Epub 2016 Jan 21.
Ware J, Kosinski M, Dewey JE How to score version 2 of the SF- 36 health survey. Lincoln, RI: QualityMetric Incorporated; 2000 p 229: 2000.
Washburn RA, Smith KW, Jette AM, Janney CA The Physical Activity Scale for the Elderly (PASE): development and evaluation. J Clin Epidemiol. 1993 Feb;46(2):153-62. doi: 10.1016/0895-4356(93)90053-4.
Wrenn KD, Murphy F, Slovis CM A toxicity study of parenteral thiamine hydrochloride. Ann Emerg Med. 1989 Aug;18(8):867-70. doi: 10.1016/s0196-0644(89)80215-x.
Zheng Y, Li D, Zeng N, Guo H, Li H, Shen S Trends of antihypertensive agents in patients with hypertension and coronary artery disease in a tertiary hospital of China. Int J Clin Pharm. 2020 Apr;42(2):482-488. doi: 10.1007/s11096-020-00986-6. Epub 2020 Feb 20.
Thiamine Intervention and Cognition in Older Adults Undergoing Coronary Artery Bypass Grafting - A Randomized Clinical Trial.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.