Clinical trial NCT03167268 - References

Colorectal Cancer Metastatic — Panitumumab Skin Toxicity Prevention Trial

Citation(s)

•   Chen J, Song Y, Zhang L
  Effect of lycopene supplementation on oxidative stress: an exploratory systematic review and meta-analysis of randomized controlled trials. J Med Food. 2013 May;16(5):361-74. doi: 10.1089/jmf.2012.2682. Epub 2013 Apr 30. Review.
•   Di Franco R, Calvanese M, Murino P, Manzo R, Guida C, Di Gennaro D, Anania C, Ravo V
  Skin toxicity from external beam radiation therapy in breast cancer patients: protective effects of Resveratrol, Lycopene, Vitamin C and anthocianin (Ixor®). Radiat Onco
•   Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocákova I, Ruff P, Blasinska-Morawiec M, Šmakal M, Canon JL, Rother M, Oliner KS, Tian Y, Xu F, Sidhu R
  Final results from PRIME:
•   Galimont-Collen AF, Vos LE, Lavrijsen AP, Ouwerkerk J, Gelderblom H
  Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors. Eur J Cancer. 2007 Mar;43(5):845-51. Epub 2007 Feb 7. Re
•   Hu JC, Sadeghi P, Pinter-Brown LC, Yashar S, Chiu MW
  Cutaneous side effects of epidermal growth factor receptor inhibitors: clinical presentation, pathogenesis, and management. J Am Acad Dermatol. 2007 Feb;56(2):317-26. Epub 2006 Dec 1. Review.
•   Kahn M
  Can we safely target the WNT pathway? Nat Rev Drug Discov. 2014 Jul;13(7):513-32. doi: 10.1038/nrd4233. Review.
•   Kasdagly M, Radhakrishnan S, Reddivari L, Veeramachaneni DN, Vanamala J
  Colon carcinogenesis: influence of Western diet-induced obesity and targeting stem cells using dietary bioactive compounds. Nutrition. 2014 Nov-Dec;30(11-12):1242-56. doi: 10.1016/j.
•   Khuda-Bukhsh AR, Das S, Saha SK
  Molecular approaches toward targeted cancer prevention with some food plants and their products: inflammatory and other signal pathways. Nutr Cancer. 2014;66(2):194-205. doi: 10.1080/01635581.2014.864420. Epub 2013 Dec 30.
•   Kim M, Jho EH
  Cross-talk between Wnt/ß-catenin and Hippo signaling pathways: a brief review. BMB Rep. 2014 Oct;47(10):540-5. Review.
•   Lacouture ME, Maitland ML, Segaert S, Setser A, Baran R, Fox LP, Epstein JB, Barasch A, Einhorn L, Wagner L, West DP, Rapoport BL, Kris MG, Basch E, Eaby B, Kurtin S, Olsen EA, Chen A, Dancey JE, Trotti A
  A proposed EGFR inhibitor dermatologic adverse ev
•   Lemieux E, Cagnol S, Beaudry K, Carrier J, Rivard N
  Oncogenic KRAS signalling promotes the Wnt/ß-catenin pathway through LRP6 in colorectal cancer. Oncogene. 2015 Sep 17;34(38):4914-27. doi: 10.1038/onc.2014.416. Epub 2014 Dec 15.
•   Li Y, Wicha MS, Schwartz SJ, Sun D
  Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds. J Nutr Biochem. 2011 Sep;22(9):799-806. doi: 10.1016/j.jnutbio.2010.11.001. Epub 2011 Feb 4. Review.
•   Misale S, Di Nicolantonio F, Sartore-Bianchi A, Siena S, Bardelli A
  Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution. Cancer Discov. 2014 Nov;4(11):1269-80. doi: 10.1158/2159-8290.CD-14-0462. Epub 2014 Oct
•   Pastore S, Mascia F, Mariani V, Girolomoni G
  The epidermal growth factor receptor system in skin repair and inflammation. J Invest Dermatol. 2008 Jun;128(6):1365-74. Epub 2007 Nov 29. Review.
•   Preet R, Mohapatra P, Das D, Satapathy SR, Choudhuri T, Wyatt MD, Kundu CN
  Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC. Carcinogenesis. 2013 Feb;34(2):277-86. doi: 10.1093/carcin/bgs
•   Requena C, Llombart B, Sanmartín O
  Acneiform eruptions induced by epidermal growth factor receptor inhibitors: treatment with oral isotretinoin. Cutis. 2012 Aug;90(2):77-80.
•   Rodeck U
  Skin toxicity caused by EGFR antagonists-an autoinflammatory condition triggered by deregulated IL-1 signaling? J Cell Physiol. 2009 Jan;218(1):32-4. doi: 10.1002/jcp.21585. Review.
•   Sarkar FH, Li Y, Wang Z, Kong D
  The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer. Cancer Metastasis Rev. 2010 Sep;29(3):383-94. doi: 10.1007/s10555-010-9233-4. Review.
•   Shao A, Hathcock JN
  Risk assessment for the carotenoids lutein and lycopene. Regul Toxicol Pharmacol. 2006 Aug;45(3):289-98. Epub 2006 Jun 30. Review.
•   Stahl W, Sies H
  ß-Carotene and other carotenoids in protection from sunlight. Am J Clin Nutr. 2012 Nov;96(5):1179S-84S. doi: 10.3945/ajcn.112.034819. Epub 2012 Oct 10. Review.
•   Tang FY, Pai MH, Wang XD
  Consumption of lycopene inhibits the growth and progression of colon cancer in a mouse xenograft model. J Agric Food Chem. 2011 Aug 24;59(16):9011-21. doi: 10.1021/jf2017644. Epub 2011 Jul 25.
•   Tang FY, Shih CJ, Cheng LH, Ho HJ, Chen HJ
  Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway. Mol Nutr Food Res. 2008 Jun;52(6):646-54. doi: 10.1002/mnfr.200700272.

Double-blind, Phase II Study to Assess the Effectiveness of Lycopene vs Placebo to Reduce Skin Toxicity in Patients With Colorectal Carcinoma Treated With Panitumumab

Details for clinical trial NCT03167268