Bolwerk CA Effects of relaxing music on state anxiety in myocardial infarction patients. Crit Care Nurs Q. 1990 Sep;13(2):63-72.
Byers JF, Smyth KA Effect of a music intervention on noise annoyance, heart rate, and blood pressure in cardiac surgery patients. Am J Crit Care. 1997 May;6(3):183-91.
El-Hassan H, McKeown K, Muller AF Clinical trial: music reduces anxiety levels in patients attending for endoscopy. Aliment Pharmacol Ther. 2009 Oct;30(7):718-24. doi: 10.1111/j.1365-2036.2009.04091.x. Epub 2009 Jul 8.
Flegal KM, Carroll MD, Ogden CL, Curtin LR Prevalence and trends in obesity among US adults, 1999-2008. JAMA. 2010 Jan 20;303(3):235-41. doi: 10.1001/jama.2009.2014. Epub 2010 Jan 13.
Guzzetta CE Effects of relaxation and music therapy on patients in a coronary care unit with presumptive acute myocardial infarction. Heart Lung. 1989 Nov;18(6):609-16.
Kotwal MR, Rinchhen CZ, Ringe VV Stress reduction through listening to Indian classical music during gastroscopy. Diagn Ther Endosc. 1998;4(4):191-7. doi: 10.1155/DTE.4.191.
Oddby-Muhrbeck E, Jakobsson J Recall of music: a comparison between anaesthesia with propofol and isoflurane. Acta Anaesthesiol Scand. 1993 Jan;37(1):33-7.
Qadeer MA, Rocio Lopez A, Dumot JA, Vargo JJ Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients. Dig Dis Sci. 2009 May;54(5):1035-40. doi: 10.1007/s10620-008-0452-2. Epub 2008 Nov 12.
Wang SM, Kulkarni L, Dolev J, Kain ZN Music and preoperative anxiety: a randomized, controlled study. Anesth Analg. 2002 Jun;94(6):1489-94, table of contents.
White JM Music therapy: an intervention to reduce anxiety in the myocardial infarction patient. Clin Nurse Spec. 1992 Summer;6(2):58-63.
Zhang XW, Fan Y, Manyande A, Tian YK, Yin P Effects of music on target-controlled infusion of propofol requirements during combined spinal-epidural anaesthesia. Anaesthesia. 2005 Oct;60(10):990-4.
Music Utilization in Sedation and Induction in Colonoscopy
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.