NCT04512612 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Cubiella J, Castells A, Andreu M, Bujanda L, Carballo F, Jover R, Lanas Á, Morillas JD, Salas D, Quintero E; COLONPREV study investigators
Correlation between adenoma detection rate in colonoscopy- and fecal immunochemical testing-based colorectal cancer
Pohl J, Schneider A, Vogell H, Mayer G, Kaiser G, Ell C
Pancolonic chromoendoscopy with indigo carmine versus standard colonoscopy for detection of neoplastic lesions: a randomised two-centre trial. Gut. 2011 Apr;60(4):485-90. doi: 10.1136/gut.2010.22953

Can Pan-Colonic Chromoendoscopy (PCC) Improve Adenoma Detection Rate in FIT-Positive-Patients: A Randomized Study

Clinical trial NCT04512612 - References