Bastani F, Khosravi M, Borimnejad L, Arbabi N The effect of acupressure on cancer-related fatigue among school-aged children with acute lymphoblastic leukemia. Iran J Nurs Midwifery Res. 2015 Sep-Oct;20(5):545-51. doi: 10.4103/1735-9066.164508.
Das R, Nayak BS, Margaret B Acupressure and physical stress among high school students. Holist Nurs Pract. 2011 Mar-Apr;25(2):97-104. doi: 10.1097/HNP.0b013e31820d784a.
Jones E, Isom S, Kemper KJ, McLean TW Acupressure for chemotherapy-associated nausea and vomiting in children. J Soc Integr Oncol. 2008 Fall;6(4):141-5.
Koc Ozkan T, Simsek Kucukkelepce D, Aydin Ozkan S The effects of acupressure and foot massage on pain during heel lancing in neonates: A randomized controlled trial. Complement Ther Med. 2019 Oct;46:103-108. doi: 10.1016/j.ctim.2019.08.004. Epub 2019 Aug 6.
Liu CF, Chien LW Efficacy of acupuncture in children with asthma: a systematic review. Ital J Pediatr. 2015 Jul 7;41:48. doi: 10.1186/s13052-015-0155-1.
Norheim AJ, Liodden I, Howley M Implementation of acupuncture and acupressure under surgical procedures in children: a pilot study. Acupunct Med. 2010 Jun;28(2):71-3. doi: 10.1136/aim.2009.002220. Epub 2010 May 10.
Pour PS, Ameri GF, Kazemi M, Jahani Y Comparison of Effects of Local Anesthesia and Two-Point Acupressure on the Severity of Venipuncture Pain Among Hospitalized 6-12-Year-Old Children. J Acupunct Meridian Stud. 2017 Jun;10(3):187-192. doi: 10.1016/j.jams.2017.04.001. Epub 2017 Apr 24.
Tanju O, Fatma Yilmaz K Effect of acupressure on procedural pain before heel lancing in neonates. J Tradit Chin Med. 2021 Apr;41(2):331-337.
Unesi Z , Sajed A, Sharifzadeh G R The Effects of Manual Pressure on the Injection Site on Vaccination Pain Among Infants: A Two-Group Clinical Trial. Mod Care J. 2019;16(4):e95705. doi: 10.5812/modernc.95705.
Yeh CH, Chien LC, Chiang YC, Lin SW, Huang CK, Ren D Reduction in nausea and vomiting in children undergoing cancer chemotherapy by either appropriate or sham auricular acupuncture points with standard care. J Altern Complement Med. 2012 Apr;18(4):334-40. doi: 10.1089/acm.2011.0102.
The Effect of Acupressure on Interventional Pain in Infancy Period Before Immunization: A Randomized Placebo-Controlled Trial
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
