NCT05099627 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Baron EM, Young WF
Cervical spondylotic myelopathy: a brief review of its pathophysiology, clinical course, and diagnosis. Neurosurgery. 2007 Jan;60(1 Supp1 1):S35-41. Review.
Hopkins BS, Weber KA 2nd, Kesavabhotla K, Paliwal M, Cantrell DR, Smith ZA
Machine Learning for the Prediction of Cervical Spondylotic Myelopathy: A Post Hoc Pilot Study of 28 Participants. World Neurosurg. 2019 Jul;127:e436-e442. doi: 10.1016/j.wneu.201
Merali Z, Wang JZ, Badhiwala JH, Witiw CD, Wilson JR, Fehlings MG
A deep learning model for detection of cervical spinal cord compression in MRI scans. Sci Rep. 2021 May 18;11(1):10473. doi: 10.1038/s41598-021-89848-3.
Merali ZG, Witiw CD, Badhiwala JH, Wilson JR, Fehlings MG
Using a machine learning approach to predict outcome after surgery for degenerative cervical myelopathy. PLoS One. 2019 Apr 4;14(4):e0215133. doi: 10.1371/journal.pone.0215133. eCollection 2019.

A Point-of-care Machine Learning Model and Scoring System for the Early Diagnosis and Prediction of Treatment Outcome in Patients With Cervical Myelopathy: an Ambispective Cohort Study.

Details for clinical trial NCT05099627

Clinical trial NCT05099627 - References