Roll SC, Takata SC, Yao B, Kysh L, Mack WJ Sonographic reference values for median nerve cross-sectional area: A meta-analysis of data from healthy individuals. J Diagn Med Sonogr. 2023 Sep;39(5):492-506. doi: 10.1177/87564793231176009. Epub 2023 Jun 6.
Takata SC, Kysh L, Mack WJ, Roll SC Sonographic reference values of median nerve cross-sectional area: a protocol for a systematic review and meta-analysis. Syst Rev. 2019 Jan 3;8(1):2. doi: 10.1186/s13643-018-0929-9.
Takata SC, Roll SC Identification of Aberrant Muscle Bellies in the Carpal Tunnel using Sonography. J Diagn Med Sonogr. 2019 Jan;35(1):62-68. doi: 10.1177/8756479318807469. Epub 2018 Oct 20.
Yao B, Gan K, Lee A, Roll SC Comparing Shape Categorization to Circularity Measurement in the Evaluation of Median Nerve Compression Using Sonography. J Diagn Med Sonogr. 2020;2020:10.1177/8756479319898471. doi: 10.1177/8756479319898471. Epub 2020 Jan 8.
Yao B, Roll SC An ultrasound study of the mobility of the median nerve during composite finger movement in the healthy young wrist. Muscle Nerve. 2022 Jan;65(1):82-88. doi: 10.1002/mus.27437. Epub 2021 Oct 27.
Yao B, Takata SC, Mack WJ, Roll SC Modeling extracurricular activity participation with physical and mental health in college students over time. J Am Coll Health. 2023 May-Jun;71(4):1232-1240. doi: 10.1080/07448481.2021.1926263. Epub 2021 Jul 9.
Sonographic Tissue Morphology in Early Stage Work-related Median Nerve Pathology
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
