Clinical trial NCT00005176 - References

Cardiovascular Diseases — Long QT Syndrome-Population Genetics and Cardiac Studies

Citation(s)

•   Ali RH, Zareba W, Moss AJ, Schwartz PJ, Benhorin J, Vincent GM, Locati EH, Priori S, Napolitano C, Towbin JA, Hall WJ, Robinson JL, Andrews ML, Zhang L, Timothy K, Medina A
  Clinical and genetic variables associated with acute arousal and nonarousal-related cardiac events among subjects with long QT syndrome. Am J Cardiol. 2000 Feb 15;85(4):457-61.
•   Barsheshet A, Moss AJ, McNitt S, Polonsky S, Lopes CM, Zareba W, Robinson JL, Ackerman MJ, Benhorin J, Kaufman ES, Towbin JA, Vincent GM, Qi M, Goldenberg I
  Risk of syncope in family members who are genotype-negative for a family-associated long-QT syndrome mutation. Circ Cardiovasc Genet. 2011 Oct;4(5):491-9. doi: 10.1161/CIRCGENETICS.111.960179. Epub 2011 Aug 10.
•   Barsheshet A, Peterson DR, Moss AJ, Schwartz PJ, Kaufman ES, McNitt S, Polonsky S, Buber J, Zareba W, Robinson JL, Ackerman MJ, Benhorin J, Towbin JA, Vincent GM, Zhang L, Goldenberg I
  Genotype-specific QT correction for heart rate and the risk of life-threatening cardiac events in adolescents with congenital long-QT syndrome. Heart Rhythm. 2011 Aug;8(8):1207-13. doi: 10.1016/j.hrthm.2011.03.009. Epub 2011 Mar 10.
•   Benhorin J, Goldmit M, MacCluer JW, Blangero J, Goffen R, Leibovitch A, Rahat A, Wang Q, Medina A, Towbin J, Kerem B
  Identification of a new SCN5A mutation, D1840G, associated with the long QT syndrome. Mutations in brief no. 153. Online. Hum Mutat. 1998;12(1):72.
•   Benhorin J, Merri M, Alberti M, Locati E, Moss AJ, Hall WJ, Cui L
  Long QT syndrome. New electrocardiographic characteristics. Circulation. 1990 Aug;82(2):521-7.
•   Benhorin J, Moss AJ, Bak M, Zareba W, Kaufman ES, Kerem B, Towbin JA, Priori S, Kass RS, Attali B, Brown AM, Ficker E
  Variable expression of long QT syndrome among gene carriers from families with five different HERG mutations. Ann Noninvasive Electrocardiol. 2002 Jan;7(1):40-6.
•   Benhorin J, Taub R, Goldmit M, Kerem B, Kass RS, Windman I, Medina A
  Effects of flecainide in patients with new SCN5A mutation: mutation-specific therapy for long-QT syndrome? Circulation. 2000 Apr 11;101(14):1698-706.
•   Burattini L, Zareba W, Rashba EJ, Couderc JP, Konecki J, Moss AJ
  ECG features of microvolt T-wave alternans in coronary artery disease and long QT syndrome patients. J Electrocardiol. 1998;31 Suppl:114-20.
•   Chen Q, Zhang D, Gingell RL, Moss AJ, Napolitano C, Priori SG, Schwartz PJ, Kehoe E, Robinson JL, Schulze-Bahr E, Wang Q, Towbin JA
  Homozygous deletion in KVLQT1 associated with Jervell and Lange-Nielsen syndrome. Circulation. 1999 Mar 16;99(10):1344-7.
•   Couderc JP, McNitt S, Xia J, Zareba W, Moss AJ
  Repolarization morphology in adult LQT2 carriers with borderline prolonged QTc interval. Heart Rhythm. 2006 Dec;3(12):1460-6. Epub 2006 Aug 10.
•   Couderc JP, Vaglio M, Xia X, McNitt S, Wicker P, Sarapa N, Moss AJ, Zareba W
  Impaired T-amplitude adaptation to heart rate characterizes I(Kr) inhibition in the congenital and acquired forms of the long QT syndrome. J Cardiovasc Electrophysiol. 2007 Dec;18(12):1299-305. Epub 2007 Oct 4.
•   Couderc JP, Xia X, Peterson DR, McNitt S, Zhao H, Polonsky S, Moss AJ, Zareba W
  T-wave morphology abnormalities in benign, potent, and arrhythmogenic I(kr) inhibition. Heart Rhythm. 2011 Jul;8(7):1036-43. doi: 10.1016/j.hrthm.2011.02.005. Epub 2011 Feb 9.
•   Couderc JP, Zareba W, Burattini L, Konecki JA, Moss AJ
  Beat-to-beat repolarization variability in amplitude and duration in LQTS patients with the SCN5A sodium channel gene mutation. J Electrocardiol. 1998;31 Suppl:134.
•   Couderc JP, Zareba W, Burattini L, Moss AJ
  Beat-to-Beat repolarization variability in LQTS patients with the SCN5A sodium channel gene mutation. Pacing Clin Electrophysiol. 1999 Nov;22(11):1581-92.
•   Crotti L, Spazzolini C, Schwartz PJ, Shimizu W, Denjoy I, Schulze-Bahr E, Zaklyazminskaya EV, Swan H, Ackerman MJ, Moss AJ, Wilde AA, Horie M, Brink PA, Insolia R, De Ferrari GM, Crimi G
  The common long-QT syndrome mutation KCNQ1/A341V causes unusually severe clinical manifestations in patients with different ethnic backgrounds: toward a mutation-specific risk stratification. Circulation. 2007 Nov 20;116(21):2366-75. Epub 2007 Nov 5.
•   Curran M, Atkinson D, Timothy K, Vincent GM, Moss AJ, Leppert M, Keating M
  Locus heterogeneity of autosomal dominant long QT syndrome. J Clin Invest. 1993 Aug;92(2):799-803.
•   Daubert JP, Zareba W, Rosero SZ, Budzikowski A, Robinson JL, Moss AJ
  Role of implantable cardioverter defibrillator therapy in patients with long QT syndrome. Am Heart J. 2007 Apr;153(4 Suppl):53-8. Review.
•   De Ambroggi L, Bertoni T, Locati E, Stramba-Badiale M, Schwartz PJ
  Mapping of body surface potentials in patients with the idiopathic long QT syndrome. Circulation. 1986 Dec;74(6):1334-45.
•   De Ambroggi L, Negroni MS, Monza E, Bertoni T, Schwartz PJ
  Dispersion of ventricular repolarization in the long QT syndrome. Am J Cardiol. 1991 Sep 1;68(6):614-20.
•   De Ferrari GM, Nador F, Beria G, Sala S, Lotto A, Schwartz PJ
  Effect of calcium channel block on the wall motion abnormality of the idiopathic long QT syndrome. Circulation. 1994 May;89(5):2126-32.
•   Fugate T 2nd, Moss AJ, Jons C, McNitt S, Mullally J, Ouellet G, Goldenberg I, Zareba W, Robinson JL; U
  S. portion of International Long QT Syndrome Registry Investigators. Long QT syndrome in African-Americans. Ann Noninvasive Electrocardiol. 2010 Jan;15(1):73-6. doi: 10.1111/j.1542-474X.2009.00342.x.
•   Goldenberg I, Bradley J, Moss A, McNitt S, Polonsky S, Robinson JL, Andrews M, Zareba W; International LQTS Registry Investigators
  Beta-blocker efficacy in high-risk patients with the congenital long-QT syndrome types 1 and 2: implications for patient management. J Cardiovasc Electrophysiol. 2010 Aug 1;21(8):893-901. doi: 10.1111/j.1540-8167.2010.01737.x. Epub 2010 Mar 5.
•   Goldenberg I, Horr S, Moss AJ, Lopes CM, Barsheshet A, McNitt S, Zareba W, Andrews ML, Robinson JL, Locati EH, Ackerman MJ, Benhorin J, Kaufman ES, Napolitano C, Platonov PG, Priori SG, Qi M, Schwartz PJ, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Zhang L
  Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals. J Am Coll Cardiol. 2011 Jan 4;57(1):51-9. doi: 10.1016/j.jacc.2010.07.038.
•   Goldenberg I, Mathew J, Moss AJ, McNitt S, Peterson DR, Zareba W, Benhorin J, Zhang L, Vincent GM, Andrews ML, Robinson JL, Morray B
  Corrected QT variability in serial electrocardiograms in long QT syndrome: the importance of the maximum corrected QT for risk stratification. J Am Coll Cardiol. 2006 Sep 5;48(5):1047-52. Epub 2006 Jul 7.
•   Goldenberg I, Moss AJ, Bradley J, Polonsky S, Peterson DR, McNitt S, Zareba W, Andrews ML, Robinson JL, Ackerman MJ, Benhorin J, Kaufman ES, Locati EH, Napolitano C, Priori SG, Qi M, Schwartz PJ, Towbin JA, Vincent GM, Zhang L
  Long-QT syndrome after age 40. Circulation. 2008 Apr 29;117(17):2192-201. doi: 10.1161/CIRCULATIONAHA.107.729368. Epub 2008 Apr 21.
•   Goldenberg I, Moss AJ, Maron BJ, Dick AW, Zareba W
  Cost-effectiveness of implanted defibrillators in young people with inherited cardiac arrhythmias. Ann Noninvasive Electrocardiol. 2005 Oct;10(4 Suppl):67-83.
•   Goldenberg I, Moss AJ, Peterson DR, McNitt S, Zareba W, Andrews ML, Robinson JL, Locati EH, Ackerman MJ, Benhorin J, Kaufman ES, Napolitano C, Priori SG, Qi M, Schwartz PJ, Towbin JA, Vincent GM, Zhang L
  Risk factors for aborted cardiac arrest and sudden cardiac death in children with the congenital long-QT syndrome. Circulation. 2008 Apr 29;117(17):2184-91. doi: 10.1161/CIRCULATIONAHA.107.701243. Epub 2008 Apr 21.
•   Goldenberg I, Moss AJ, Zareba W, McNitt S, Robinson JL, Qi M, Towbin JA, Ackerman MJ, Murphy L
  Clinical course and risk stratification of patients affected with the Jervell and Lange-Nielsen syndrome. J Cardiovasc Electrophysiol. 2006 Nov;17(11):1161-8. Epub 2006 Aug 14.
•   Goldenberg I, Moss AJ, Zareba W
  Sudden cardiac death without structural heart disease: update on the long QT and Brugada syndromes. Curr Cardiol Rep. 2005 Sep;7(5):349-56. Review.
•   Goldenberg I, Moss AJ
  Long QT syndrome. J Am Coll Cardiol. 2008 Jun 17;51(24):2291-300. doi: 10.1016/j.jacc.2008.02.068. Review.
•   Goldenberg I, Thottathil P, Lopes CM, Moss AJ, McNitt S, O-Uchi J, Robinson JL, Zareba W, Ackerman MJ, Kaufman ES, Towbin JA, Vincent M, Barsheshet A
  Trigger-specific ion-channel mechanisms, risk factors, and response to therapy in type 1 long QT syndrome. Heart Rhythm. 2012 Jan;9(1):49-56. doi: 10.1016/j.hrthm.2011.08.020. Epub 2011 Aug 24.
•   Goldenberg I, Zareba W, Moss AJ
  Long QT Syndrome. Curr Probl Cardiol. 2008 Nov;33(11):629-94. doi: 10.1016/j.cpcardiol.2008.07.002. Review.
•   Hobbs JB, Peterson DR, Moss AJ, McNitt S, Zareba W, Goldenberg I, Qi M, Robinson JL, Sauer AJ, Ackerman MJ, Benhorin J, Kaufman ES, Locati EH, Napolitano C, Priori SG, Towbin JA, Vincent GM, Zhang L
  Risk of aborted cardiac arrest or sudden cardiac death during adolescence in the long-QT syndrome. JAMA. 2006 Sep 13;296(10):1249-54.
•   Horr S, Goldenberg I, Moss AJ, O-Uchi J, Barsheshet A, Connelly H, Gray DA, Zareba W, Lopes CM
  Ion channel mechanisms related to sudden cardiac death in phenotype-negative long-QT syndrome genotype-phenotype correlations of the KCNQ1(S349W) mutation. J Cardiovasc Electrophysiol. 2011 Feb;22(2):193-200. doi: 10.1111/j.1540-8167.2010.01852.x.
•   Jiang C, Atkinson D, Towbin JA, Splawski I, Lehmann MH, Li H, Timothy K, Taggart RT, Schwartz PJ, Vincent GM, et al
  Two long QT syndrome loci map to chromosomes 3 and 7 with evidence for further heterogeneity. Nat Genet. 1994 Oct;8(2):141-7.
•   Jons C, Moss AJ, Goldenberg I, Liu J, McNitt S, Zareba W, Qi M, Robinson JL
  Risk of fatal arrhythmic events in long QT syndrome patients after syncope. J Am Coll Cardiol. 2010 Feb 23;55(8):783-8. doi: 10.1016/j.jacc.2009.11.042.
•   Karp JM, Moss AJ
  Dental treatment of patients with long QT syndrome. J Am Dent Assoc. 2006 May;137(5):630-7. Review.
•   Kaufman ES, McNitt S, Moss AJ, Zareba W, Robinson JL, Hall WJ, Ackerman MJ, Benhorin J, Locati ET, Napolitano C, Priori SG, Schwartz PJ, Towbin JA, Vincent GM, Zhang L
  Risk of death in the long QT syndrome when a sibling has died. Heart Rhythm. 2008 Jun;5(6):831-6. doi: 10.1016/j.hrthm.2008.02.029. Epub 2008 Mar 4.
•   Kim JA, Lopes CM, Moss AJ, McNitt S, Barsheshet A, Robinson JL, Zareba W, Ackerman MJ, Kaufman ES, Towbin JA, Vincent M, Goldenberg I
  Trigger-specific risk factors and response to therapy in long QT syndrome type 2. Heart Rhythm. 2010 Dec;7(12):1797-805. doi: 10.1016/j.hrthm.2010.09.011. Epub 2010 Sep 17.
•   Kimbrough J, Moss AJ, Zareba W, Robinson JL, Hall WJ, Benhorin J, Locati EH, Medina A, Napolitano C, Priori S, Schwartz PJ, Timothy K, Towbin JA, Vincent GM, Zhang L
  Clinical implications for affected parents and siblings of probands with long-QT syndrome. Circulation. 2001 Jul 31;104(5):557-62.
•   Kupershmidt S, Yang T, Chanthaphaychith S, Wang Z, Towbin JA, Roden DM
  Defective human Ether-à-go-go-related gene trafficking linked to an endoplasmic reticulum retention signal in the C terminus. J Biol Chem. 2002 Jul 26;277(30):27442-8. Epub 2002 May 20.
•   Lane RD, Reis HT, Peterson DR, Zareba W, Moss AJ
  Happiness and stress alter susceptibility to cardiac events in Long QT Syndrome. Ann Noninvasive Electrocardiol. 2009 Apr;14(2):193-200. doi: 10.1111/j.1542-474X.2009.00295.x.
•   Li H, Chen Q, Moss AJ, Robinson J, Goytia V, Perry JC, Vincent GM, Priori SG, Lehmann MH, Denfield SW, Duff D, Kaine S, Shimizu W, Schwartz PJ, Wang Q, Towbin JA
  New mutations in the KVLQT1 potassium channel that cause long-QT syndrome. Circulation. 1998 Apr 7;97(13):1264-9.
•   Liu JF, Goldenberg I, Moss AJ, Shimizu W, Wilde AA, Hofman N, McNitt S, Zareba W, Miyamato Y, Robinson JL, Andrews ML
  Phenotypic variability in Caucasian and Japanese patients with matched LQT1 mutations. Ann Noninvasive Electrocardiol. 2008 Jul;13(3):234-41. doi: 10.1111/j.1542-474X.2008.00226.x.
•   Liu JF, Jons C, Moss AJ, McNitt S, Peterson DR, Qi M, Zareba W, Robinson JL, Barsheshet A, Ackerman MJ, Benhorin J, Kaufman ES, Locati EH, Napolitano C, Priori SG, Schwartz PJ, Towbin J, Vincent M, Zhang L, Goldenberg I; International Long QT Syndrome Registry
  Risk factors for recurrent syncope and subsequent fatal or near-fatal events in children and adolescents with long QT syndrome. J Am Coll Cardiol. 2011 Feb 22;57(8):941-50. doi: 10.1016/j.jacc.2010.10.025. Erratum in: J Am Coll Cardiol. 2011 Apr 19;57(16):1717.
•   Locati E, Schwartz PJ, Moss AJ, Crampton RS: Long-Term Survival After Left Cervico-Thoracic Sympathectomy in High Risk Long QT Syndrome Patients With Refractory Ventricular Arrhythmias
  J Am Coll Cardiol, 7:234A, 1986
•   Locati EH, Zareba W, Moss AJ, Schwartz PJ, Vincent GM, Lehmann MH, Towbin JA, Priori SG, Napolitano C, Robinson JL, Andrews M, Timothy K, Hall WJ
  Age- and sex-related differences in clinical manifestations in patients with congenital long-QT syndrome: findings from the International LQTS Registry. Circulation. 1998 Jun 9;97(22):2237-44.
•   Malfatto G, Beria G, Sala S, Bonazzi O, Schwartz PJ
  Quantitative analysis of T wave abnormalities and their prognostic implications in the idiopathic long QT syndrome. J Am Coll Cardiol. 1994 Feb;23(2):296-301.
•   Merri M, Benhorin J, Alberti M, Locati E, Moss AJ
  Electrocardiographic quantitation of ventricular repolarization. Circulation. 1989 Nov;80(5):1301-8.
•   Merri M, Moss AJ, Benhorin J, Locati EH, Alberti M, Badilini F
  Relation between ventricular repolarization duration and cardiac cycle length during 24-hour Holter recordings. Findings in normal patients and patients with long QT syndrome. Circulation. 1992 May;85(5):1816-21.
•   Migdalovich D, Moss AJ, Lopes CM, Costa J, Ouellet G, Barsheshet A, McNitt S, Polonsky S, Robinson JL, Zareba W, Ackerman MJ, Benhorin J, Kaufman ES, Platonov PG, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Goldenberg I
  Mutation and gender-specific risk in type 2 long QT syndrome: implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome. Heart Rhythm. 2011 Oct;8(10):1537-43. doi: 10.1016/j.hrthm.2011.03.049. Epub 2011 Mar 25.
•   Moss AJ, Liu JE, Gottlieb S, Locati EH, Schwartz PJ, Robinson JL
  Efficacy of permanent pacing in the management of high-risk patients with long QT syndrome. Circulation. 1991 Oct;84(4):1524-9.
•   Moss AJ, Merri M, Benhorin J, Alberti M, Locati E
  Multidimensional quantitation of ventricular repolarization. Static and dynamic characteristics. Ann N Y Acad Sci. 1990;601:31-5.
•   Moss AJ, Robinson J
  Clinical features of the idiopathic long QT syndrome. Circulation. 1992 Jan;85(1 Suppl):I140-4. Review.
•   Moss AJ, Robinson JL, Gessman L, Gillespie R, Zareba W, Schwartz PJ, Vincent GM, Benhorin J, Heilbron EL, Towbin JA, Priori SG, Napolitano C, Zhang L, Medina A, Andrews ML, Timothy K
  Comparison of clinical and genetic variables of cardiac events associated with loud noise versus swimming among subjects with the long QT syndrome. Am J Cardiol. 1999 Oct 15;84(8):876-9.
•   Moss AJ, Robinson JL
  Clinical aspects of the idiopathic long QT syndrome. Ann N Y Acad Sci. 1992 Jan 27;644:103-11.
•   Moss AJ, Robinson JL
  Long QT syndrome. Heart Dis Stroke. 1992 Sep-Oct;1(5):309-14. Review.
•   Moss AJ, Robinson JL
  The long-QT syndrome Genetic considerations. Trends Cardiovasc Med. 1992 May-Jun;2(3):81-3. doi: 10.1016/1050-1738(92)90010-P.
•   Moss AJ, Schwartz PJ, Crampton RS, Tzivoni D, Locati EH, MacCluer J, Hall WJ, Weitkamp L, Vincent GM, Garson A Jr, et al
  The long QT syndrome. Prospective longitudinal study of 328 families. Circulation. 1991 Sep;84(3):1136-44.
•   Moss AJ, Schwartz PJ
  25th anniversary of the International Long-QT Syndrome Registry: an ongoing quest to uncover the secrets of long-QT syndrome. Circulation. 2005 Mar 8;111(9):1199-201. Review.
•   Moss AJ, Shimizu W, Wilde AA, Towbin JA, Zareba W, Robinson JL, Qi M, Vincent GM, Ackerman MJ, Kaufman ES, Hofman N, Seth R, Kamakura S, Miyamoto Y, Goldenberg I, Andrews ML, McNitt S
  Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene. Circulation. 2007 May 15;115(19):2481-9. Epub 2007 Apr 30.
•   Moss AJ, Zareba W, Hall WJ, Schwartz PJ, Crampton RS, Benhorin J, Vincent GM, Locati EH, Priori SG, Napolitano C, Medina A, Zhang L, Robinson JL, Timothy K, Towbin JA, Andrews ML
  Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome. Circulation. 2000 Feb 15;101(6):616-23.
•   Moss AJ
  Clinical management of patients with the long QT syndrome: drugs, devices, and gene-specific therapy. Pacing Clin Electrophysiol. 1997 Aug;20(8 Pt 2):2058-60. Review.
•   Moss AJ
  Long QT Syndrome. JAMA. 2003 Apr 23-30;289(16):2041-4. Review.
•   Moss AJ
  Long QT Syndromes. Curr Treat Options Cardiovasc Med. 2000 Aug;2(4):317-322.
•   Moss AJ
  Management of patients with the hereditary long QT syndrome. J Cardiovasc Electrophysiol. 1998 Jun;9(6):668-74.
•   Moss AJ
  Measurement of the QT interval and the risk associated with QTc interval prolongation: a review. Am J Cardiol. 1993 Aug 26;72(6):23B-25B. Review.
•   Moss AJ
  Prolonged QT-interval syndromes. JAMA. 1986 Dec 5;256(21):2985-7. Erratum in: JAMA 1987 Jan 23-20;257(4):487.
•   Moss AJ
  Sex hormones and ventricular tachyarrhythmias in LQTS: new insights regarding antiarrhythmic therapy. Heart Rhythm. 2012 May;9(5):833-4. doi: 10.1016/j.hrthm.2012.01.014. Epub 2012 Jan 20.
•   Moss AJ
  T-wave patterns associated with the hereditary long QT syndrome. Card Electrophysiol Rev. 2002 Sep;6(3):311-5. Review.
•   Moss AJ
  The long QT syndrome revisited: current understanding and implications for treatment. Pacing Clin Electrophysiol. 1997 Dec;20(12 Pt 1):2879-81.
•   Nador F, Beria G, De Ferrari GM, Stramba-Badiale M, Locati EH, Lotto A, Schwartz PJ
  Unsuspected echocardiographic abnormality in the long QT syndrome. Diagnostic, prognostic, and pathogenetic implications. Circulation. 1991 Oct;84(4):1530-42.
•   Ning L, Moss A, Zareba W, Robinson J, Rosero S, Ryan D, Qi M
  Denaturing high-performance liquid chromatography quickly and reliably detects cardiac ion channel mutations in long QT syndrome. Genet Test. 2003 Fall;7(3):249-53.
•   Ning L, Moss AJ, Zareba W, Robinson J, Rosero S, Ryan D, Qi M
  Novel compound heterozygous mutations in the KCNQ1 gene associated with autosomal recessive long QT syndrome (Jervell and Lange-Nielsen syndrome). Ann Noninvasive Electrocardiol. 2003 Jul;8(3):246-50.
•   Ouellet G, Moss AJ, Jons C, McNitt S, Mullally J, Fugate T, Goldenberg I, Zareba W, Robinson JL; Investigators from the U
  S. Portion of the International Long QT Syndrome Registry. Influence of diabetes mellitus on outcome in patients over 40 years of age with the long QT syndrome. Am J Cardiol. 2010 Jan 1;105(1):87-9. doi: 10.1016/j.amjcard.2009.08.657. Epub 2009 Oct 23.
•   Patrick CC, Goust JM, Virella G
  Tolerance and autoimmunity. Immunol Ser. 1990;50:415-33. Review.
•   Perkiömäki JS, Zareba W, Couderc JP, Moss AJ
  Heart rate variability in patients with congenital long QT syndrome. Ann Noninvasive Electrocardiol. 2001 Oct;6(4):298-304.
•   Perkiömäki JS, Zareba W, Nomura A, Andrews M, Kaufman ES, Moss AJ
  Repolarization dynamics in patients with long QT syndrome. J Cardiovasc Electrophysiol. 2002 Jul;13(7):651-6.
•   Rashba EJ, Zareba W, Moss AJ, Hall WJ, Robinson J, Locati EH, Schwartz PJ, Andrews M
  Influence of pregnancy on the risk for cardiac events in patients with hereditary long QT syndrome. LQTS Investigators. Circulation. 1998 Feb 10;97(5):451-6.
•   Rosero SZ, Zareba W, Moss AJ, Robinson JL, Hajj Ali RH, Locati EH, Benhorin J, Andrews ML
  Asthma and the risk of cardiac events in the Long QT syndrome. Long QT Syndrome Investigative Group. Am J Cardiol. 1999 Dec 15;84(12):1406-11.
•   Schwartz PJ, Locati EH, Moss AJ, Crampton RS, Trazzi R, Ruberti U
  Left cardiac sympathetic denervation in the therapy of congenital long QT syndrome. A worldwide report. Circulation. 1991 Aug;84(2):503-11.
•   Schwartz PJ, Moss AJ, Vincent GM, Crampton RS
  Diagnostic criteria for the long QT syndrome. An update. Circulation. 1993 Aug;88(2):782-4. Review.
•   Schwartz PJ, Priori SG, Cerrone M, Spazzolini C, Odero A, Napolitano C, Bloise R, De Ferrari GM, Klersy C, Moss AJ, Zareba W, Robinson JL, Hall WJ, Brink PA, Toivonen L, Epstein AE, Li C, Hu D
  Left cardiac sympathetic denervation in the management of high-risk patients affected by the long-QT syndrome. Circulation. 2004 Apr 20;109(15):1826-33. Epub 2004 Mar 29.
•   Schwartz PJ, Priori SG, Locati EH, Napolitano C, Cantù F, Towbin JA, Keating MT, Hammoude H, Brown AM, Chen LS, Colatsky TJ
  Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy. Circulation. 1995 Dec 15;92(12):3381-6.
•   Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, Denjoy I, Guicheney P, Breithardt G, Keating MT, Towbin JA, Beggs AH, Brink P, Wilde AA, Toivonen L, Zareba W, Robinson JL, Timothy KW, Corfield V, Wattanasirichaigoon D, Corbett C, Haverkamp W, Schulze-Bahr E, Lehmann MH, Schwartz K, Coumel P, Bloise R
  Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation. 2001 Jan 2;103(1):89-95.
•   Schwartz PJ, Zaza A, Locati E, Moss AJ
  Stress and sudden death. The case of the long QT syndrome. Circulation. 1991 Apr;83(4 Suppl):II71-80. Review.
•   Seth R, Moss AJ, McNitt S, Zareba W, Andrews ML, Qi M, Robinson JL, Goldenberg I, Ackerman MJ, Benhorin J, Kaufman ES, Locati EH, Napolitano C, Priori SG, Schwartz PJ, Towbin JA, Vincent GM, Zhang L
  Long QT syndrome and pregnancy. J Am Coll Cardiol. 2007 Mar 13;49(10):1092-8. Epub 2007 Feb 27.
•   Shimizu W, Moss AJ, Wilde AA, Towbin JA, Ackerman MJ, January CT, Tester DJ, Zareba W, Robinson JL, Qi M, Vincent GM, Kaufman ES, Hofman N, Noda T, Kamakura S, Miyamoto Y, Shah S, Amin V, Goldenberg I, Andrews ML, McNitt S
  Genotype-phenotype aspects of type 2 long QT syndrome. J Am Coll Cardiol. 2009 Nov 24;54(22):2052-62. doi: 10.1016/j.jacc.2009.08.028.
•   Spazzolini C, Mullally J, Moss AJ, Schwartz PJ, McNitt S, Ouellet G, Fugate T, Goldenberg I, Jons C, Zareba W, Robinson JL, Ackerman MJ, Benhorin J, Crotti L, Kaufman ES, Locati EH, Qi M, Napolitano C, Priori SG, Towbin JA, Vincent GM
  Clinical implications for patients with long QT syndrome who experience a cardiac event during infancy. J Am Coll Cardiol. 2009 Aug 25;54(9):832-7. doi: 10.1016/j.jacc.2009.05.029.
•   Splawski I, Shen J, Timothy KW, Lehmann MH, Priori S, Robinson JL, Moss AJ, Schwartz PJ, Towbin JA, Vincent GM, Keating MT
  Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2. Circulation. 2000 Sep 5;102(10):1178-85.
•   Sze E, Moss AJ, Goldenberg I, McNitt S, Jons C, Zareba W, Qi M, Robinson JL; International Long QT Syndrome Investigative Group
  Long QT syndrome in patients over 40 years of age: increased risk for LQTS-related cardiac events in patients with coronary disease. Ann Noninvasive Electrocardiol. 2008 Oct;13(4):327-31. doi: 10.1111/j.1542-474X.2008.00250.x.
•   Tan HL, Bardai A, Shimizu W, Moss AJ, Schulze-Bahr E, Noda T, Wilde AA
  Genotype-specific onset of arrhythmias in congenital long-QT syndrome: possible therapy implications. Circulation. 2006 Nov 14;114(20):2096-103. Epub 2006 Nov 6.
•   Thottathil P, Acharya J, Moss AJ, Jons C, McNitt S, Goldenberg I, Zareba W, Kaufman E, Qi M, Robinson JL; International Long QT Syndrome Investigative Group
  Risk of cardiac events in patients with asthma and long-QT syndrome treated with beta(2) agonists. Am J Cardiol. 2008 Oct 1;102(7):871-4. doi: 10.1016/j.amjcard.2008.05.029. Epub 2008 Jul 17.
•   Treherne JM, Woodward SK, Varga ZM, Ritchie JM, Nicholls JG
  Restoration of conduction and growth of axons through injured spinal cord of neonatal opossum in culture. Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):431-4.
•   Vaglio M, Couderc JP, McNitt S, Xia X, Moss AJ, Zareba W
  A quantitative assessment of T-wave morphology in LQT1, LQT2, and healthy individuals based on Holter recording technology. Heart Rhythm. 2008 Jan;5(1):11-8. doi: 10.1016/j.hrthm.2007.08.026. Epub 2007 Aug 28.
•   Vincent GM: The Heart Rate of Romano-Ward Long QT Syndrome Patients
  Circulation, 72(III):44, 1986
•   Wang Q, Shen J, Splawski I, Atkinson D, Li Z, Robinson JL, Moss AJ, Towbin JA, Keating MT
  SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Cell. 1995 Mar 10;80(5):805-11.
•   Wang Z, Li H, Moss AJ, Robinson J, Zareba W, Knilans T, Bowles NE, Towbin JA
  Compound heterozygous mutations in KvLQT1 cause Jervell and Lange-Nielsen syndrome. Mol Genet Metab. 2002 Apr;75(4):308-16.
•   Weitkamp LR, Moss AJ, Lewis RA, Hall WJ, MacCluer JW, Schwartz PJ, Locati EH, Tzivoni D, Vincent GM, Robinson JL, et al
  Analysis of HLA and disease susceptibility: chromosome 6 genes and sex influence long-QT phenotype. Am J Hum Genet. 1994 Dec;55(6):1230-41.
•   Weitkamp LR, Moss AJ: The Long QT (Romano-Ward) Syndrome Locus, LQT, is Probably Linked to the HLA Loci
  Cytogenet Cell Genet, 40:775, 1985
•   Windle JR, Geletka RC, Moss AJ, Zareba W, Atkins DL
  Normalization of ventricular repolarization with flecainide in long QT syndrome patients with SCN5A:DeltaKPQ mutation. Ann Noninvasive Electrocardiol. 2001 Apr;6(2):153-8.
•   Wu G, Ai T, Kim JJ, Mohapatra B, Xi Y, Li Z, Abbasi S, Purevjav E, Samani K, Ackerman MJ, Qi M, Moss AJ, Shimizu W, Towbin JA, Cheng J, Vatta M
  alpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruption. Circ Arrhythm Electrophysiol. 2008 Aug;1(3):193-201. doi: 10.1161/CIRCEP.108.769224.
•   Zareba W, Cygankiewicz I
  Long QT syndrome and short QT syndrome. Prog Cardiovasc Dis. 2008 Nov-Dec;51(3):264-78. doi: 10.1016/j.pcad.2008.10.006. Review.
•   Zareba W, Moss AJ, Daubert JP, Hall WJ, Robinson JL, Andrews M
  Implantable cardioverter defibrillator in high-risk long QT syndrome patients. J Cardiovasc Electrophysiol. 2003 Apr;14(4):337-41.
•   Zareba W, Moss AJ, Konecki J
  TU wave area-derived measures of repolarization dispersion in the long QT syndrome. J Electrocardiol. 1998;30 Suppl:191-5.
•   Zareba W, Moss AJ, le Cessie S, Hall WJ
  T wave alternans in idiopathic long QT syndrome. J Am Coll Cardiol. 1994 Jun;23(7):1541-6.
•   Zareba W, Moss AJ, le Cessie S, Locati EH, Robinson JL, Hall WJ, Andrews ML
  Risk of cardiac events in family members of patients with long QT syndrome. J Am Coll Cardiol. 1995 Dec;26(7):1685-91.
•   Zareba W, Moss AJ, Locati EH, Lehmann MH, Peterson DR, Hall WJ, Schwartz PJ, Vincent GM, Priori SG, Benhorin J, Towbin JA, Robinson JL, Andrews ML, Napolitano C, Timothy K, Zhang L, Medina A; International Long QT Syndrome Registry
  Modulating effects of age and gender on the clinical course of long QT syndrome by genotype. J Am Coll Cardiol. 2003 Jul 2;42(1):103-9.
•   Zareba W, Moss AJ, Schwartz PJ, Vincent GM, Robinson JL, Priori SG, Benhorin J, Locati EH, Towbin JA, Keating MT, Lehmann MH, Hall WJ
  Influence of genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group. N Engl J Med. 1998 Oct 1;339(14):960-5.
•   Zareba W, Moss AJ, Sheu G, Kaufman ES, Priori S, Vincent GM, Towbin JA, Benhorin J, Schwartz PJ, Napolitano C, Hall WJ, Keating MT, Qi M, Robinson J, Andrews ML; International LQTS Registry, University of Rochester, Rochester, New York
  Location of mutation in the KCNQ1 and phenotypic presentation of long QT syndrome. J Cardiovasc Electrophysiol. 2003 Nov;14(11):1149-53.
•   Zareba W, Moss AJ
  Dispersion of repolarization. Relation to heart rate and repolarization duration. J Electrocardiol. 1995;28 Suppl:202-6.
•   Zareba W, Moss AJ
  Long QT syndrome in children. J Electrocardiol. 2001;34 Suppl:167-71.
•   Zareba W
  Counting mRNA in blood of LQTS - new direction? Kardiol Pol. 2011;69(5):430.
•   Zareba W
  Genotype-specific ECG patterns in long QT syndrome. J Electrocardiol. 2006 Oct;39(4 Suppl):S101-6. Epub 2006 Sep 11. Review.
•   Zhang L, Timothy KW, Vincent GM, Lehmann MH, Fox J, Giuli LC, Shen J, Splawski I, Priori SG, Compton SJ, Yanowitz F, Benhorin J, Moss AJ, Schwartz PJ, Robinson JL, Wang Q, Zareba W, Keating MT, Towbin JA, Napolitano C, Medina A
  Spectrum of ST-T-wave patterns and repolarization parameters in congenital long-QT syndrome: ECG findings identify genotypes. Circulation. 2000 Dec 5;102(23):2849-55.
•   Zhang T, Moss A, Cong P, Pan M, Chang B, Zheng L, Fang Q, Zareba W, Robinson J, Lin C, Li Z, Wei J, Zeng Q; Long QT International Registry Investigators; HVP-China Investigators, Qi M
  LQTS gene LOVD database. Hum Mutat. 2010 Nov;31(11):E1801-10. doi: 10.1002/humu.21341.

Long QT Syndrome-Population Genetics and Cardiac Studies

Details for clinical trial NCT00005176