Clinical trial NCT00005313 - References

Cardiovascular Diseases — Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined Hyperlipidemia

Citation(s)

•   Angelin B, Hershon KS, Brunzell JD
  Bile acid metabolism in hereditary forms of hypertriglyceridemia: evidence for an increased synthesis rate in monogenic familial hypertriglyceridemia. Proc Natl Acad Sci U S A. 1987 Aug;84(15):5434-8.
•   Austin MA, Brunzell JD, Fitch WL, Krauss RM
  Inheritance of low density lipoprotein subclass patterns in familial combined hyperlipidemia. Arteriosclerosis. 1990 Jul-Aug;10(4):520-30.
•   Austin MA, Hokanson JE, Brunzell JD
  Characterization of low-density lipoprotein subclasses: methodologic approaches and clinical relevance. Curr Opin Lipidol. 1994 Dec;5(6):395-403. Review.
•   Austin MA, Wijsman E, Guo SW, Krauss RM, Brunzell JD, Deeb S
  Lack of evidence for linkage between low-density lipoprotein subclass phenotypes and the apolipoprotein B locus in familial combined hyperlipidemia. Genet Epidemiol. 1991;8(5):287-97.
•   Auwerx JH, Babirak SP, Fujimoto WY, Iverius PH, Brunzell JD
  Defective enzyme protein in lipoprotein lipase deficiency. Eur J Clin Invest. 1989 Oct;19(5):433-7.
•   Auwerx JH, Babirak SP, Hokanson JE, Stahnke G, Will H, Deeb SS, Brunzell JD
  Coexistence of abnormalities of hepatic lipase and lipoprotein lipase in a large family. Am J Hum Genet. 1990 Mar;46(3):470-7.
•   Auwerx JH, Deeb S, Brunzell JD, Peng R, Chait A
  Transcriptional activation of the lipoprotein lipase and apolipoprotein E genes accompanies differentiation in some human macrophage-like cell lines. Biochemistry. 1988 Apr 19;27(8):2651-5.
•   Auwerx JH, Deeb S, Brunzell JD, Wolfbauer G, Chait A
  Lipoprotein lipase gene expression in THP-1 cells. Biochemistry. 1989 May 30;28(11):4563-7.
•   Auwerx JH, Marzetta CA, Hokanson JE, Brunzell JD
  Large buoyant LDL-like particles in hepatic lipase deficiency. Arteriosclerosis. 1989 May-Jun;9(3):319-25.
•   Babirak SP, Iverius PH, Fujimoto WY, Brunzell JD
  Detection and characterization of the heterozygote state for lipoprotein lipase deficiency. Arteriosclerosis. 1989 May-Jun;9(3):326-34.
•   Brown BG, Zambon A, Poulin D, Rocha A, Maher VM, Davis JW, Albers JJ, Brunzell JD
  Use of niacin, statins, and resins in patients with combined hyperlipidemia. Am J Cardiol. 1998 Feb 26;81(4A):52B-59B. Review.
•   Bruin T, Kastelein JJ, Van Diermen DE, Ma Y, Henderson HE, Stuyt PM, Stalenhoef AF, Sturk A, Brunzell JD, Hayden MR
  A missense mutation Pro157 Arg in lipoprotein lipase (LPLNijmegen) resulting in loss of catalytic activity. Eur J Biochem. 1992 Sep 1;208(2):267-72.
•   Brunzell JD, Austin MA
  Individuality, hyperlipidemia, and premature coronary artery disease. World Rev Nutr Diet. 1990;63:72-83. Review.
•   Brunzell JD, Fujimoto WY
  Body fat distribution and dyslipidemia. Am J Med. 1995 Nov;99(5):457-8.
•   Brunzell JD, Hokanson JE
  Dyslipidemia of central obesity and insulin resistance. Diabetes Care. 1999 Apr;22 Suppl 3:C10-3. Review.
•   Brunzell JD, Hokanson JE
  Low-density and high-density lipoprotein subspecies and risk for premature coronary artery disease. Am J Med. 1999 Aug 23;107(2A):16S-18S. Review.
•   Brunzell JD, Iverius PH, Scheibel MS, Fujimoto WY, Hayden MR, McLeod R, Frolich J
  Primary lipoprotein lipase deficiency. Adv Exp Med Biol. 1986;201:227-39. Review.
•   Brunzell JD, Sniderman AD, Albers JJ, Kwiterovich PO Jr
  Apoproteins B and A-I and coronary artery disease in humans. Arteriosclerosis. 1984 Mar-Apr;4(2):79-83. Review.
•   Brunzell JD
  Are all obese patients at risk for cardiovascular disease? Int J Obes. 1984;8(5):571-8. Review.
•   Carr MC, Brunzell JD
  Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk. J Clin Endocrinol Metab. 2004 Jun;89(6):2601-7. Review.
•   Carr MC, Hokanson JE, Deeb SS, Purnell JQ, Mitchell ES, Brunzell JD
  A hepatic lipase gene promoter polymorphism attenuates the increase in hepatic lipase activity with increasing intra-abdominal fat in women. Arterioscler Thromb Vasc Biol. 1999 Nov;19(11):2701-7.
•   Carr MC, Hokanson JE, Zambon A, Deeb SS, Barrett PH, Purnell JQ, Brunzell JD
  The contribution of intraabdominal fat to gender differences in hepatic lipase activity and low/high density lipoprotein heterogeneity. J Clin Endocrinol Metab. 2001 Jun;86(6):2831-7.
•   Carr MC, Kim KH, Zambon A, Mitchell ES, Woods NF, Casazza CP, Purnell JQ, Hokanson JE, Brunzell JD, Schwartz RS
  Changes in LDL density across the menopausal transition. J Investig Med. 2000 Jul;48(4):245-50.
•   Chait A, Foster DM, Albers JJ, Failor RA, Brunzell JD
  Low density lipoprotein metabolism in familial combined hyperlipidemia and familial hypercholesterolemia: kinetic analysis using an integrated model. Metabolism. 1986 Aug;35(8):697-704.
•   Deeb S, Failor A, Brown BG, Brunzell JD, Albers JJ, Motulsky AG
  Molecular genetics of apolipoproteins and coronary heart disease. Cold Spring Harb Symp Quant Biol. 1986;51 Pt 1:403-9.
•   Deeb SS, Failor RA, Brown BG, Brunzell JD, Albers JJ, Motulsky AG, Wijsman E
  Association of apolipoprotein B gene variants with plasma apoB and low density lipoprotein (LDL) cholesterol levels. Hum Genet. 1992 Feb;88(4):463-70.
•   Deeb SS, Nevin DN, Iwasaki L, Brunzell JD
  Two novel apolipoprotein A-IV variants in individuals with familial combined hyperlipidemia and diminished levels of lipoprotein lipase activity. Hum Mutat. 1996;8(4):319-25.
•   Devlin RH, Deeb S, Brunzell J, Hayden MR
  Partial gene duplication involving exon-Alu interchange results in lipoprotein lipase deficiency. Am J Hum Genet. 1990 Jan;46(1):112-9.
•   Emmerich J, Beg OU, Peterson J, Previato L, Brunzell JD, Brewer HB Jr, Santamarina-Fojo S
  Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241. J Biol Chem. 1992 Feb 25;267(6):4161-5.
•   Foster DM, Chait A, Albers JJ, Failor RA, Harris C, Brunzell JD
  Evidence for kinetic heterogeneity among human low density lipoproteins. Metabolism. 1986 Aug;35(8):685-96.
•   Franz MJ, Bantle JP, Beebe CA, Brunzell JD, Chiasson JL, Garg A, Holzmeister LA, Hoogwerf B, Mayer-Davis E, Mooradian AD, Purnell JQ, Wheeler M
  Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. Diabetes Care. 2002 Jan;25(1):148-98. Review.
•   Hokanson JE, Austin MA, Zambon A, Brunzell JD
  Plasma triglyceride and LDL heterogeneity in familial combined hyperlipidemia. Arterioscler Thromb. 1993 Mar;13(3):427-34.
•   Hokanson JE, Brunzell JD, Jarvik GP, Wijsman EM, Austin MA
  Linkage of low-density lipoprotein size to the lipoprotein lipase gene in heterozygous lipoprotein lipase deficiency. Am J Hum Genet. 1999 Feb;64(2):608-18.
•   Hokanson JE, Krauss RM, Albers JJ, Austin MA, Brunzell JD
  LDL physical and chemical properties in familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 1995 Apr;15(4):452-9.
•   Iverius PH, Brunzell JD
  Chylomicronemia induced by cimetidine. Gastroenterology. 1985 Sep;89(3):664-6.
•   Iverius PH, Brunzell JD
  Human adipose tissue lipoprotein lipase: changes with feeding and relation to postheparin plasma enzyme. Am J Physiol. 1985 Jul;249(1 Pt 1):E107-14.
•   Iverius PH, Brunzell JD
  Obesity and common genetic metabolic disorders. Ann Intern Med. 1985 Dec;103(6 ( Pt 2)):1050-1.
•   Iverius PH, Brunzell JD
  Relationship between lipoprotein lipase activity and plasma sex steroid level in obese women. J Clin Invest. 1988 Sep;82(3):1106-12.
•   Jarvik GP, Brunzell JD, Austin MA, Krauss RM, Motulsky AG, Wijsman E
  Genetic predictors of FCHL in four large pedigrees. Influence of ApoB level major locus predicted genotype and LDL subclass phenotype. Arterioscler Thromb. 1994 Nov;14(11):1687-94.
•   Jarvik GP, Wijsman E, Little RE, Albers JJ, Motulsky AG, Brunzell JD
  Host and environmental effects on plasma apolipoprotein B. Int J Clin Lab Res. 1993;23(4):215-20.
•   Joven J, Vilella E, Ahmad S, Cheung MC, Brunzell JD
  Lipoprotein heterogeneity in end-stage renal disease. Kidney Int. 1993 Feb;43(2):410-8.
•   Langlois S, Deeb S, Brunzell JD, Kastelein JJ, Hayden MR
  A major insertion accounts for a significant proportion of mutations underlying human lipoprotein lipase deficiency. Proc Natl Acad Sci U S A. 1989 Feb;86(3):948-52.
•   Love MW, Craddock AL, Angelin B, Brunzell JD, Duane WC, Dawson PA
  Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2001 Dec;21(12):2039-45.
•   Marzetta CA, Foster DM, Brunzell JD
  Conversion of plasma VLDL and IDL precursors into various LDL subpopulations using density gradient ultracentrifugation. J Lipid Res. 1990 Jun;31(6):975-84.
•   Marzetta CA, Foster DM, Brunzell JD
  Relationships between LDL density and kinetic heterogeneity in subjects with normolipidemia and familial combined hyperlipidemia using density gradient ultracentrifugation. J Lipid Res. 1989 Sep;30(9):1307-17.
•   McNeely MJ, Edwards KL, Marcovina SM, Brunzell JD, Motulsky AG, Austin MA
  Lipoprotein and apolipoprotein abnormalities in familial combined hyperlipidemia: a 20-year prospective study. Atherosclerosis. 2001 Dec;159(2):471-81.
•   Murdoch SJ, Carr MC, Hokanson JE, Brunzell JD, Albers JJ
  PLTP activity in premenopausal women. Relationship with lipoprotein lipase, HDL, LDL, body fat, and insulin resistance. J Lipid Res. 2000 Feb;41(2):237-44.
•   Nevin DN, Brunzell JD, Deeb SS
  The LPL gene in individuals with familial combined hyperlipidemia and decreased LPL activity. Arterioscler Thromb. 1994 Jun;14(6):869-73.
•   Purnell JQ, Kahn SE, Albers JJ, Nevin DN, Brunzell JD, Schwartz RS
  Effect of weight loss with reduction of intra-abdominal fat on lipid metabolism in older men. J Clin Endocrinol Metab. 2000 Mar;85(3):977-82.
•   Purnell JQ, Kahn SE, Schwartz RS, Brunzell JD
  Relationship of insulin sensitivity and ApoB levels to intra-abdominal fat in subjects with familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 2001 Apr;21(4):567-72.
•   Purnell JQ, Zambon A, Knopp RH, Pizzuti DJ, Achari R, Leonard JM, Locke C, Brunzell JD
  Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects. AIDS. 2000 Jan 7;14(1):51-7.
•   Reina M, Brunzell JD, Deeb SS
  Molecular basis of familial chylomicronemia: mutations in the lipoprotein lipase and apolipoprotein C-II genes. J Lipid Res. 1992 Dec;33(12):1823-32.
•   Rohlfing JJ, Brunzell JD
  The effects of diuretics and adrenergic-blocking agents on plasma lipids. West J Med. 1986 Aug;145(2):210-8. Review.
•   Ullrich NF, Purnell JQ, Brunzell JD
  Adipose tissue fatty acid composition in humans with lipoprotein lipase deficiency. J Investig Med. 2001 May;49(3):273-5.
•   Weigle DS, Sande KJ, Iverius PH, Monsen ER, Brunzell JD
  Weight loss leads to a marked decrease in nonresting energy expenditure in ambulatory human subjects. Metabolism. 1988 Oct;37(10):930-6.
•   White JR, Chait A, Klebanoff SJ, Deeb S, Brunzell JD
  Bacterial lipopolysaccharide reduces macrophage lipoprotein lipase levels: an effect that is independent of tumor necrosis factor. J Lipid Res. 1988 Oct;29(10):1379-85.
•   Wijsman EM, Brunzell JD, Jarvik GP, Austin MA, Motulsky AG, Deeb SS
  Evidence against linkage of familial combined hyperlipidemia to the apolipoprotein AI-CIII-AIV gene complex. Arterioscler Thromb Vasc Biol. 1998 Feb;18(2):215-26.
•   Yang WS, Nevin DN, Iwasaki L, Peng R, Brown BG, Brunzell JD, Deeb SS
  Regulatory mutations in the human lipoprotein lipase gene in patients with familial combined hyperlipidemia and coronary artery disease. J Lipid Res. 1996 Dec;37(12):2627-37.
•   Yang WS, Nevin DN, Peng R, Brunzell JD, Deeb SS
  A mutation in the promoter of the lipoprotein lipase (LPL) gene in a patient with familial combined hyperlipidemia and low LPL activity. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4462-6. Erratum in: Proc Natl Acad Sci U S A 1996 Jan 9;93(1):524.
•   Zambon A, Austin MA, Brown BG, Hokanson JE, Brunzell JD
  Effect of hepatic lipase on LDL in normal men and those with coronary artery disease. Arterioscler Thromb. 1993 Feb;13(2):147-53.
•   Zambon A, Brown BG, Deeb SS, Brunzell JD
  Hepatic lipase as a focal point for the development and treatment of coronary artery disease. J Investig Med. 2001 Jan;49(1):112-8.
•   Zambon A, Deeb SS, Bensadoun A, Foster KE, Brunzell JD
  In vivo evidence of a role for hepatic lipase in human apoB-containing lipoprotein metabolism, independent of its lipolytic activity. J Lipid Res. 2000 Dec;41(12):2094-9.
•   Zambon A, Deeb SS, Brown BG, Hokanson JE, Brunzell JD
  Common hepatic lipase gene promoter variant determines clinical response to intensive lipid-lowering treatment. Circulation. 2001 Feb 13;103(6):792-8.
•   Zambon A, Hashimoto SI, Brunzell JD
  Analysis of techniques to obtain plasma for measurement of levels of free fatty acids. J Lipid Res. 1993 Jun;34(6):1021-8.
•   Zambon A, Hokanson JE, Brown BG, Brunzell JD
  Evidence for a new pathophysiological mechanism for coronary artery disease regression: hepatic lipase-mediated changes in LDL density. Circulation. 1999 Apr 20;99(15):1959-64.
•   Zambon A, Torres A, Bijvoet S, Gagne C, Moorjani S, Lupien PJ, Hayden MR, Brunzell JD
  Prevention of raised low-density lipoprotein cholesterol in a patient with familial hypercholesterolaemia and lipoprotein lipase deficiency. Lancet. 1993 May 1;341(8853):1119-21.

Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined Hyperlipidemia

Details for clinical trial NCT00005313