Cardiac Disease — Respired Gases in Patients Post Cardiac Surgery
Citation(s)
Bersten A Oh's intensive care manual. Elsevier; 2014.
Bujang MA, Baharum N Sample size guideline for correlation analysis. World Journal of Social Science Research . 2016;3(1):37-46
Ciaffoni L, O'Neill DP, Couper JH, Ritchie GA, Hancock G, Robbins PA In-airway molecular flow sensing: A new technology for continuous, noninvasive monitoring of oxygen consumption in critical care. Sci Adv. 2016 Aug 10;2(8):e1600560. doi: 10.1126/sciadv.1600560. eCollection 2016 Aug.
De Maria AN, Raisinghani A Comparative overview of cardiac output measurement methods: has impedance cardiography come of age? Congest Heart Fail. 2000 Mar-Apr;6(2):60-73. doi: 10.1111/j.1527-5299.2000.80139.x.
Magor-Elliott SRM, Fullerton CJ, Richmond G, Ritchie GAD, Robbins PA A dynamic model of the body gas stores for carbon dioxide, oxygen, and inert gases that incorporates circulatory transport delays to and from the lung. J Appl Physiol (1985). 2021 May 1;130(5):1383-1397. doi: 10.1152/japplphysiol.00764.2020. Epub 2021 Jan 21.
Pugsley J, Lerner AB Cardiac output monitoring: is there a gold standard and how do the newer technologies compare? Semin Cardiothorac Vasc Anesth. 2010 Dec;14(4):274-82. doi: 10.1177/1089253210386386. Epub 2010 Nov 7.
Rodriguez Ziccardi M, Khalid N Pulmonary Artery Catheterization. 2023 Aug 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK482170/
Wilkes AR Heat and moisture exchangers and breathing system filters: their use in anaesthesia and intensive care. Part 2 - practical use, including problems, and their use with paediatric patients. Anaesthesia. 2011 Jan;66(1):40-51. doi: 10.1111/j.1365-2044.2010.06564.x. Epub 2010 Nov 30.
An Observational Study of the Relationship Between Respired Gases, Mixed Venous Oxygen Content and Cardiac Output in Mechanically Ventilated Patients Post Cardiac Surgery
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
