Carcinoma of Male Breast — Sense of Hope Alleviates Fatigue in Breast Cancer Survivors
Citation(s)
Alexander S, Minton O, Andrews P, Stone P A comparison of the characteristics of disease-free breast cancer survivors with or without cancer-related fatigue syndrome. Eur J Cancer. 2009 Feb;45(3):384-92. doi: 10.1016/j.ejca.2008.09.010. Epub 2008 Oct 30.
Berger AM, Gerber LH, Mayer DK Cancer-related fatigue: implications for breast cancer survivors. Cancer. 2012 Apr 15;118(8 Suppl):2261-9. doi: 10.1002/cncr.27475. Review.
Dizon DS Quality of life after breast cancer: survivorship and sexuality. Breast J. 2009 Sep-Oct;15(5):500-4. doi: 10.1111/j.1524-4741.2009.00766.x. Epub 2009 Jul 14.
Hoffman AJ, von Eye A, Gift AG, Given BA, Given CW, Rothert M Testing a theoretical model of perceived self-efficacy for cancer-related fatigue self-management and optimal physical functional status. Nurs Res. 2009 Jan-Feb;58(1):32-41. doi: 10.1097/NNR.0b013e3181903d7b.
Howard-Anderson J, Ganz PA, Bower JE, Stanton AL Quality of life, fertility concerns, and behavioral health outcomes in younger breast cancer survivors: a systematic review. J Natl Cancer Inst. 2012 Mar 7;104(5):386-405. doi: 10.1093/jnci/djr541. Epub 2012 Jan 23. Review.
Mattioli JL, Repinski R, Chappy SL The meaning of hope and social support in patients receiving chemotherapy. Oncol Nurs Forum. 2008 Sep;35(5):822-9. doi: 10.1188/08.ONF.822-829.
Olson K A new way of thinking about fatigue: a reconceptualization. Oncol Nurs Forum. 2007 Jan;34(1):93-9. Review.
Piper BF, Cella D Cancer-related fatigue: definitions and clinical subtypes. J Natl Compr Canc Netw. 2010 Aug;8(8):958-66.
Rustøen T, Cooper BA, Miaskowski C The importance of hope as a mediator of psychological distress and life satisfaction in a community sample of cancer patients. Cancer Nurs. 2010 Jul-Aug;33(4):258-67. doi: 10.1097/NCC.0b013e3181d6fb61.
Trudel-Fitzgerald C, Savard J, Ivers H Evolution of cancer-related symptoms over an 18-month period. J Pain Symptom Manage. 2013 Jun;45(6):1007-18. doi: 10.1016/j.jpainsymman.2012.06.009. Epub 2012 Sep 24.
The Sense of Hope Alleviates Fatigue in Breast Cancer Survivors
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.