Clinical trial NCT03191955 - References

Cachexia — Muscle Wasting in Cancer (MWIC)

Citation(s)

•   Acharyya S, Butchbach ME, Sahenk Z, Wang H, Saji M, Carathers M, Ringel MD, Skipworth RJ, Fearon KC, Hollingsworth MA, Muscarella P, Burghes AH, Rafael-Fortney JA, Guttridge DC
  Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia. Cancer Cell. 2005 Nov;8(5):421-32. doi: 10.1016/j.ccr.2005.10.004.
•   Awad S, Tan BH, Cui H, Bhalla A, Fearon KC, Parsons SL, Catton JA, Lobo DN
  Marked changes in body composition following neoadjuvant chemotherapy for oesophagogastric cancer. Clin Nutr. 2012 Feb;31(1):74-7. doi: 10.1016/j.clnu.2011.08.008. Epub 2011 Aug 27.
•   Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, Garry PJ, Lindeman RD
  Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998 Apr 15;147(8):755-63. doi: 10.1093/oxfordjournals.aje.a009520. Erratum In: Am J Epidemiol 1999 Jun 15;149(12):1161.
•   Brzeszczynska J, Johns N, Schilb A, Degen S, Degen M, Langen R, Schols A, Glass DJ, Roubenoff R, Greig CA, Jacobi C, Fearon KCh, Ross JA
  Loss of oxidative defense and potential blockade of satellite cell maturation in the skeletal muscle of patients with cancer but not in the healthy elderly. Aging (Albany NY). 2016 Aug;8(8):1690-702. doi: 10.18632/aging.101006.
•   Charlson ME, Pompei P, Ales KL, MacKenzie CR
  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373-83. doi: 10.1016/0021-9681(87)90171-8.
•   Das SK, Eder S, Schauer S, Diwoky C, Temmel H, Guertl B, Gorkiewicz G, Tamilarasan KP, Kumari P, Trauner M, Zimmermann R, Vesely P, Haemmerle G, Zechner R, Hoefler G
  Adipose triglyceride lipase contributes to cancer-associated cachexia. Science. 2011 Jul 8;333(6039):233-8. doi: 10.1126/science.1198973. Epub 2011 Jun 16. Erratum In: Science. 2011 Sep 16;333(6049):1576.
•   Deans DA, Tan BH, Ross JA, Rose-Zerilli M, Wigmore SJ, Howell WM, Grimble RF, Fearon KC
  Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy. Am J Clin Nutr. 2009 Apr;89(4):1164-72. doi: 10.3945/ajcn.2008.27025. Epub 2009 Feb 25.
•   Deans DA, Tan BH, Wigmore SJ, Ross JA, de Beaux AC, Paterson-Brown S, Fearon KC
  The influence of systemic inflammation, dietary intake and stage of disease on rate of weight loss in patients with gastro-oesophageal cancer. Br J Cancer. 2009 Jan 13;100(1):63-9. doi: 10.1038/sj.bjc.6604828.
•   Deans DA, Wigmore SJ, Gilmour H, Paterson-Brown S, Ross JA, Fearon KC
  Elevated tumour interleukin-1beta is associated with systemic inflammation: A marker of reduced survival in gastro-oesophageal cancer. Br J Cancer. 2006 Dec 4;95(11):1568-75. doi: 10.1038/sj.bjc.6603446. Epub 2006 Nov 7.
•   Eley HL, Skipworth RJ, Deans DA, Fearon KC, Tisdale MJ
  Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2alpha may signal skeletal muscle atrophy in weight-losing cancer patients. Br J Cancer. 2008 Jan 29;98(2):443-9. doi: 10.1038/sj.bjc.6604150. Epub 2007 Dec 18.
•   Fearon K, Strasser F, Anker SD, Bosaeus I, Bruera E, Fainsinger RL, Jatoi A, Loprinzi C, MacDonald N, Mantovani G, Davis M, Muscaritoli M, Ottery F, Radbruch L, Ravasco P, Walsh D, Wilcock A, Kaasa S, Baracos VE
  Definition and classification of cancer cachexia: an international consensus. Lancet Oncol. 2011 May;12(5):489-95. doi: 10.1016/S1470-2045(10)70218-7. Epub 2011 Feb 4.
•   Fearon KC, Preston T
  Body composition in cancer cachexia. Infusionstherapie. 1990 Apr;17 Suppl 3:63-6. doi: 10.1159/000222558. No abstract available.
•   Fearon KC
  Cancer cachexia and fat-muscle physiology. N Engl J Med. 2011 Aug 11;365(6):565-7. doi: 10.1056/NEJMcibr1106880. No abstract available.
•   Grose D, Morrison DS, Devereux G, Jones R, Sharma D, Selby C, Docherty K, McIntosh D, Louden G, Nicolson M, McMillan DC, Milroy R; Scottish Lung Cancer Forum
  Comorbidities in lung cancer: prevalence, severity and links with socioeconomic status and treatment. Postgrad Med J. 2014 Jun;90(1064):305-10. doi: 10.1136/postgradmedj-2013-132186. Epub 2014 Mar 27.
•   Husi H, Barr JB, Skipworth RJ, Stephens NA, Greig CA, Wackerhage H, Barron R, Fearon KC, Ross JA
  The Human Urinary Proteome Fingerprint Database UPdb. Int J Proteomics. 2013;2013:760208. doi: 10.1155/2013/760208. Epub 2013 Oct 9.
•   Husi H, Skipworth RJ, Cronshaw A, Stephens NA, Wackerhage H, Greig C, Fearon KC, Ross JA
  Programmed cell death 6 interacting protein (PDCD6IP) and Rabenosyn-5 (ZFYVE20) are potential urinary biomarkers for upper gastrointestinal cancer. Proteomics Clin Appl. 2015 Jun;9(5-6):586-96. doi: 10.1002/prca.201400111. Epub 2015 May 8.
•   Johns N, Stephens NA, Fearon KC
  Muscle wasting in cancer. Int J Biochem Cell Biol. 2013 Oct;45(10):2215-29. doi: 10.1016/j.biocel.2013.05.032. Epub 2013 Jun 11.
•   Johns N, Stephens NA, Preston T
  Muscle protein kinetics in cancer cachexia. Curr Opin Support Palliat Care. 2012 Dec;6(4):417-23. doi: 10.1097/SPC.0b013e328359e6dd.
•   Khal J, Hine AV, Fearon KC, Dejong CH, Tisdale MJ
  Increased expression of proteasome subunits in skeletal muscle of cancer patients with weight loss. Int J Biochem Cell Biol. 2005 Oct;37(10):2196-206. doi: 10.1016/j.biocel.2004.10.017. Epub 2004 Dec 7.
•   MacDonald AJ, Greig CA, Baracos V
  The advantages and limitations of cross-sectional body composition analysis. Curr Opin Support Palliat Care. 2011 Dec;5(4):342-9. doi: 10.1097/SPC.0b013e32834c49eb.
•   Mourtzakis M, Prado CM, Lieffers JR, Reiman T, McCargar LJ, Baracos VE
  A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care. Appl Physiol Nutr Metab. 2008 Oct;33(5):997-1006. doi: 10.1139/H08-075.
•   Mracek T, Stephens NA, Gao D, Bao Y, Ross JA, Ryden M, Arner P, Trayhurn P, Fearon KC, Bing C
  Enhanced ZAG production by subcutaneous adipose tissue is linked to weight loss in gastrointestinal cancer patients. Br J Cancer. 2011 Feb 1;104(3):441-7. doi: 10.1038/sj.bjc.6606083. Epub 2011 Jan 18.
•   Rolfson DB, Majumdar SR, Tsuyuki RT, Tahir A, Rockwood K
  Validity and reliability of the Edmonton Frail Scale. Age Ageing. 2006 Sep;35(5):526-9. doi: 10.1093/ageing/afl041. Epub 2006 Jun 6. No abstract available.
•   Skipworth RJ, Husi H, Ross JA
  How close are we to finding noninvasive markers for upper GI tract cancer? Future Oncol. 2011 Oct;7(10):1121-4. doi: 10.2217/fon.11.90. No abstract available.
•   Skipworth RJ, Stene GB, Dahele M, Hendry PO, Small AC, Blum D, Kaasa S, Trottenberg P, Radbruch L, Strasser F, Preston T, Fearon KC, Helbostad JL; European Palliative Care Research Collaborative (EPCRC)
  Patient-focused endpoints in advanced cancer: criterion-based validation of accelerometer-based activity monitoring. Clin Nutr. 2011 Dec;30(6):812-21. doi: 10.1016/j.clnu.2011.05.010. Epub 2011 Jul 5.
•   Skipworth RJ, Stewart GD, Bhana M, Christie J, Sturgeon CM, Guttridge DC, Cronshaw AD, Fearon KC, Ross JA
  Mass spectrometric detection of candidate protein biomarkers of cancer cachexia in human urine. Int J Oncol. 2010 Apr;36(4):973-82. doi: 10.3892/ijo_00000577.
•   Stephens NA, Gallagher IJ, Rooyackers O, Skipworth RJ, Tan BH, Marstrand T, Ross JA, Guttridge DC, Lundell L, Fearon KC, Timmons JA
  Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia. Genome Med. 2010 Jan 15;2(1):1. doi: 10.1186/gm122.
•   Stephens NA, Skipworth RJ, Fearon KC
  Cachexia, survival and the acute phase response. Curr Opin Support Palliat Care. 2008 Dec;2(4):267-74. doi: 10.1097/SPC.0b013e3283186be2.
•   Stephens NA, Skipworth RJ, Gallagher IJ, Greig CA, Guttridge DC, Ross JA, Fearon KC
  Evaluating potential biomarkers of cachexia and survival in skeletal muscle of upper gastrointestinal cancer patients. J Cachexia Sarcopenia Muscle. 2015 Mar;6(1):53-61. doi: 10.1002/jcsm.12005. Epub 2015 Mar 31.
•   Stewart GD, Skipworth RJ, Pennington CJ, Lowrie AG, Deans DA, Edwards DR, Habib FK, Riddick AC, Fearon KC, Ross JA
  Variation in dermcidin expression in a range of primary human tumours and in hypoxic/oxidatively stressed human cell lines. Br J Cancer. 2008 Jul 8;99(1):126-32. doi: 10.1038/sj.bjc.6604458.
•   Tan BH, Birdsell LA, Martin L, Baracos VE, Fearon KC
  Sarcopenia in an overweight or obese patient is an adverse prognostic factor in pancreatic cancer. Clin Cancer Res. 2009 Nov 15;15(22):6973-9. doi: 10.1158/1078-0432.CCR-09-1525. Epub 2009 Nov 3.
•   Tan BH, Fladvad T, Braun TP, Vigano A, Strasser F, Deans DA, Skipworth RJ, Solheim TS, Damaraju S, Ross JA, Kaasa S, Marks DL, Baracos VE, Skorpen F, Fearon KC; European Palliative Care Research Collaborative
  P-selectin genotype is associated with the development of cancer cachexia. EMBO Mol Med. 2012 Jun;4(6):462-71. doi: 10.1002/emmm.201200231. Epub 2012 Apr 4.
•   Trappe TA, Lindquist DM, Carrithers JA
  Muscle-specific atrophy of the quadriceps femoris with aging. J Appl Physiol (1985). 2001 Jun;90(6):2070-4. doi: 10.1152/jappl.2001.90.6.2070.

Biochemical and Functional Biomarkers of Cachexia in Cancer Patients

Details for clinical trial NCT03191955