Carey TA, Carey M, Mullan RJ, Spratt CG, Spratt MB Assessing the statistical and personal significance of the method of levels. Behav Cogn Psychother. 2009 May;37(3):311-24. doi: 10.1017/S1352465809005232. Epub 2009 Apr 17.
Carey TA, Mansell W, Tai SJ A biopsychosocial model based on negative feedback and control. Front Hum Neurosci. 2014 Feb 28;8:94. doi: 10.3389/fnhum.2014.00094. eCollection 2014. Review.
Carey, T A. (2008b). Perceptual control theory and the method of levels: Further contributions to a transdiagnostic perspective. International Journal of Cognitive Therapy, 1, 237-255.
Carey, T A., Kelly, R.E., Mansell, W. & Tai, S. J. (2012). What's therapeutic about the therapeutic relationship? A hypothesis for practice informed by Perceptual Control Theory. The Cognitive Behaviour Therapist, 1-13.
Churchman, A , Mansell, W., & Tai, S. (2019). A school-based feasibility study of method of levels: a novel form of client-led counselling. Pastoral Care in Education, 37(4), 331-346
Cocklin AA, Mansell W, Emsley R, McEvoy P, Preston C, Comiskey J, Tai S Client Perceptions of Helpfulness in Therapy: a Novel Video-Rating Methodology for Examining Process Variables at Brief Intervals During a Single Session. Behav Cogn Psychother. 2017 Nov;45(6):647-660. doi: 10.1017/S1352465817000273. Epub 2017 May 22.
Davenport K, Hardy G, Tai S, Mansell W Individual experiences of psychological-based interventions for bipolar disorder: A systematic review and thematic synthesis. Psychol Psychother. 2019 Dec;92(4):499-522. doi: 10.1111/papt.12197. Epub 2018 Sep 3.
First, M B., Gibbon, M., Spitzer, R.L., & Williams, J. B. W. (2002). Structured Clinical interview for DSM-IV-TR axis 1 disorders (Research Version). New York: Biometrics Research Department, New York State Psychiatric Institute.
Gaffney H, Mansell W, Tai S Agents of change: Understanding the therapeutic processes associated with the helpfulness of therapy for mental health problems with relational agent MYLO. Digit Health. 2020 Mar 16;6:2055207620911580. doi: 10.1177/2055207620911580. eCollection 2020 Jan-Dec.
Gaffney H, Mansell W, Tai S Conversational Agents in the Treatment of Mental Health Problems: Mixed-Method Systematic Review. JMIR Ment Health. 2019 Oct 18;6(10):e14166. doi: 10.2196/14166. Review.
Griffiths R, Mansell W, Carey TA, Edge D, Emsley R, Tai SJ Method of levels therapy for first-episode psychosis: rationale, design and baseline data for the feasibility randomised controlled Next Level study. BJPsych Open. 2018 Aug 14;4(5):339-345. doi: 10.1192/bjo.2018.44. eCollection 2018 Sep.
Griffiths R, Mansell W, Edge D, Carey TA, Peel H, J Tai S 'It was me answering my own questions': Experiences of method of levels therapy amongst people with first-episode psychosis. Int J Ment Health Nurs. 2019 Jun;28(3):721-734. doi: 10.1111/inm.12576. Epub 2019 Jan 31.
Searson R, Mansell W, Lowens I, Tai S Think Effectively About Mood Swings (TEAMS): a case series of cognitive-behavioural therapy for bipolar disorders. J Behav Ther Exp Psychiatry. 2012 Jun;43(2):770-9. doi: 10.1016/j.jbtep.2011.10.001. Epub 2011 Oct 15.
Client-led Online Therapy for People Diagnosed With Bipolar Disorder
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
