Clinical trial NCT03220776 - References

Bipolar Disorder — Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics

Citation(s)

•   Altshuler LL, Bookheimer SY, Townsend J, Proenza MA, Eisenberger N, Sabb F, Mintz J, Cohen MS
  Blunted activation in orbitofrontal cortex during mania: a functional magnetic resonance imaging study. Biol Psychiatry. 2005 Nov 15;58(10):763-9. doi: 10.1016/j.biopsych.2005.09.012.
•   Anton RF, Moak DH, Latham P
  The Obsessive Compulsive Drinking Scale: a self-rated instrument for the quantification of thoughts about alcohol and drinking behavior. Alcohol Clin Exp Res. 1995 Feb;19(1):92-9. doi: 10.1111/j.1530-0277.1995.tb01475.x.
•   Anton RF, Myrick H, Baros AM, Latham PK, Randall PK, Wright TM, Stewart SH, Waid R, Malcolm R
  Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms. J Clin Psychopharmacol. 2009 Aug;29(4):334-42. doi: 10.1097/JCP.0b013e3181aba6a4.
•   Anton RF, Myrick H, Wright TM, Latham PK, Baros AM, Waid LR, Randall PK
  Gabapentin combined with naltrexone for the treatment of alcohol dependence. Am J Psychiatry. 2011 Jul;168(7):709-17. doi: 10.1176/appi.ajp.2011.10101436. Epub 2011 Mar 31.
•   Aufhaus E, Weber-Fahr W, Sack M, Tunc-Skarka N, Oberthuer G, Hoerst M, Meyer-Lindenberg A, Boettcher U, Ende G
  Absence of changes in GABA concentrations with age and gender in the human anterior cingulate cortex: a MEGA-PRESS study with symmetric editing pulse frequencies for macromolecule suppression. Magn Reson Med. 2013 Feb;69(2):317-20. doi: 10.1002/mrm.24257. Epub 2012 Apr 5.
•   Bagga D, Khushu S, Modi S, Kaur P, Bhattacharya D, Garg ML, Singh N
  Impaired visual information processing in alcohol-dependent subjects: a proton magnetic resonance spectroscopy study of the primary visual cortex. J Stud Alcohol Drugs. 2014 Sep;75(5):817-26. doi: 10.15288/jsad.2014.75.817.
•   Bak LK, Schousboe A, Waagepetersen HS
  The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer. J Neurochem. 2006 Aug;98(3):641-53. doi: 10.1111/j.1471-4159.2006.03913.x. Epub 2006 Jun 19.
•   Baker DA, McFarland K, Lake RW, Shen H, Tang XC, Toda S, Kalivas PW
  Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nat Neurosci. 2003 Jul;6(7):743-9. doi: 10.1038/nn1069.
•   Bauer J, Pedersen A, Scherbaum N, Bening J, Patschke J, Kugel H, Heindel W, Arolt V, Ohrmann P
  Craving in alcohol-dependent patients after detoxification is related to glutamatergic dysfunction in the nucleus accumbens and the anterior cingulate cortex. Neuropsychopharmacology. 2013 Jul;38(8):1401-8. doi: 10.1038/npp.2013.45. Epub 2013 Feb 12.
•   Beck A, Schlagenhauf F, Wustenberg T, Hein J, Kienast T, Kahnt T, Schmack K, Hagele C, Knutson B, Heinz A, Wrase J
  Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics. Biol Psychiatry. 2009 Oct 15;66(8):734-42. doi: 10.1016/j.biopsych.2009.04.035. Epub 2009 Jun 27.
•   Beck AT, Steer RA, Ball R, Ranieri W
  Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients. J Pers Assess. 1996 Dec;67(3):588-97. doi: 10.1207/s15327752jpa6703_13.
•   Behar KL, Rothman DL, Petersen KF, Hooten M, Delaney R, Petroff OA, Shulman GI, Navarro V, Petrakis IL, Charney DS, Krystal JH
  Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients. Am J Psychiatry. 1999 Jun;156(6):952-4. doi: 10.1176/ajp.156.6.952.
•   Benes FM, Berretta S
  GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology. 2001 Jul;25(1):1-27. doi: 10.1016/S0893-133X(01)00225-1.
•   Berk M, Copolov DL, Dean O, Lu K, Jeavons S, Schapkaitz I, Anderson-Hunt M, Bush AI
  N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial. Biol Psychiatry. 2008 Sep 15;64(6):468-75. doi: 10.1016/j.biopsych.2008.04.022. Epub 2008 Jun 5.
•   Berk M, Dean O, Cotton SM, Gama CS, Kapczinski F, Fernandes BS, Kohlmann K, Jeavons S, Hewitt K, Allwang C, Cobb H, Bush AI, Schapkaitz I, Dodd S, Malhi GS
  The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial. J Affect Disord. 2011 Dec;135(1-3):389-94. doi: 10.1016/j.jad.2011.06.005. Epub 2011 Jun 29.
•   Bermpohl F, Kahnt T, Dalanay U, Hagele C, Sajonz B, Wegner T, Stoy M, Adli M, Kruger S, Wrase J, Strohle A, Bauer M, Heinz A
  Altered representation of expected value in the orbitofrontal cortex in mania. Hum Brain Mapp. 2010 Jul;31(7):958-69. doi: 10.1002/hbm.20909.
•   Bhagwagar Z, Wylezinska M, Jezzard P, Evans J, Ashworth F, Sule A, Matthews PM, Cowen PJ
  Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects. Biol Psychiatry. 2007 Mar 15;61(6):806-12. doi: 10.1016/j.biopsych.2006.08.048. Epub 2007 Jan 8.
•   Bohn MJ, Krahn DD, Staehler BA
  Development and initial validation of a measure of drinking urges in abstinent alcoholics. Alcohol Clin Exp Res. 1995 Jun;19(3):600-6. doi: 10.1111/j.1530-0277.1995.tb01554.x.
•   Boy F, Evans CJ, Edden RA, Lawrence AD, Singh KD, Husain M, Sumner P
  Dorsolateral prefrontal gamma-aminobutyric acid in men predicts individual differences in rash impulsivity. Biol Psychiatry. 2011 Nov 1;70(9):866-72. doi: 10.1016/j.biopsych.2011.05.030. Epub 2011 Jul 14.
•   Brady RO Jr, McCarthy JM, Prescot AP, Jensen JE, Cooper AJ, Cohen BM, Renshaw PF, Ongur D
  Brain gamma-aminobutyric acid (GABA) abnormalities in bipolar disorder. Bipolar Disord. 2013 Jun;15(4):434-9. doi: 10.1111/bdi.12074. Epub 2013 May 2.
•   Brennan BP, Hudson JI, Jensen JE, McCarthy J, Roberts JL, Prescot AP, Cohen BM, Pope HG Jr, Renshaw PF, Ongur D
  Rapid enhancement of glutamatergic neurotransmission in bipolar depression following treatment with riluzole. Neuropsychopharmacology. 2010 Feb;35(3):834-46. doi: 10.1038/npp.2009.191. Epub 2009 Dec 2.
•   Brooks JO 3rd, Wang PW, Strong C, Sachs N, Hoblyn JC, Fenn R, Ketter TA
  Preliminary evidence of differential relations between prefrontal cortex metabolism and sustained attention in depressed adults with bipolar disorder and healthy controls. Bipolar Disord. 2006 Jun;8(3):248-54. doi: 10.1111/j.1399-5618.2006.00310.x.
•   Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ
  The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989 May;28(2):193-213. doi: 10.1016/0165-1781(89)90047-4.
•   Cai K, Nanga RP, Lamprou L, Schinstine C, Elliott M, Hariharan H, Reddy R, Epperson CN
  The impact of gabapentin administration on brain GABA and glutamate concentrations: a 7T (1)H-MRS study. Neuropsychopharmacology. 2012 Dec;37(13):2764-71. doi: 10.1038/npp.2012.142. Epub 2012 Aug 8.
•   Carta MG, Hardoy MC, Hardoy MJ, Grunze H, Carpiniello B
  The clinical use of gabapentin in bipolar spectrum disorders. J Affect Disord. 2003 Jun;75(1):83-91. doi: 10.1016/s0165-0327(02)00046-0.
•   Chang L, Jiang CS, Ernst T
  Effects of age and sex on brain glutamate and other metabolites. Magn Reson Imaging. 2009 Jan;27(1):142-5. doi: 10.1016/j.mri.2008.06.002. Epub 2008 Aug 6.
•   Corr PJ
  Reinforcement sensitivity theory and personality. Neurosci Biobehav Rev. 2004 May;28(3):317-32. doi: 10.1016/j.neubiorev.2004.01.005. Erratum In: Neurosci Biobehav Rev. 2005 Jan;28(8):875.
•   Dager SR, Friedman SD, Parow A, Demopulos C, Stoll AL, Lyoo IK, Dunner DL, Renshaw PF
  Brain metabolic alterations in medication-free patients with bipolar disorder. Arch Gen Psychiatry. 2004 May;61(5):450-8. doi: 10.1001/archpsyc.61.5.450.
•   Edden RA, Puts NA, Harris AD, Barker PB, Evans CJ
  Gannet: A batch-processing tool for the quantitative analysis of gamma-aminobutyric acid-edited MR spectroscopy spectra. J Magn Reson Imaging. 2014 Dec;40(6):1445-52. doi: 10.1002/jmri.24478. Epub 2013 Nov 13.
•   Ehrlich A, Schubert F, Pehrs C, Gallinat J
  Alterations of cerebral glutamate in the euthymic state of patients with bipolar disorder. Psychiatry Res. 2015 Aug 30;233(2):73-80. doi: 10.1016/j.pscychresns.2015.05.010. Epub 2015 May 22.
•   Ende G, Cackowski S, Van Eijk J, Sack M, Demirakca T, Kleindienst N, Bohus M, Sobanski E, Krause-Utz A, Schmahl C
  Impulsivity and Aggression in Female BPD and ADHD Patients: Association with ACC Glutamate and GABA Concentrations. Neuropsychopharmacology. 2016 Jan;41(2):410-8. doi: 10.1038/npp.2015.153. Epub 2015 Jun 4.
•   Ende G, Hermann D, Demirakca T, Hoerst M, Tunc-Skarka N, Weber-Fahr W, Wichert S, Rabinstein J, Frischknecht U, Mann K, Vollstadt-Klein S
  Loss of control of alcohol use and severity of alcohol dependence in non-treatment-seeking heavy drinkers are related to lower glutamate in frontal white matter. Alcohol Clin Exp Res. 2013 Oct;37(10):1643-9. doi: 10.1111/acer.12149. Epub 2013 Jun 25.
•   Fatemi SH, Stary JM, Earle JA, Araghi-Niknam M, Eagan E
  GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum. Schizophr Res. 2005 Jan 1;72(2-3):109-22. doi: 10.1016/j.schres.2004.02.017. Erratum In: Schizophr Res. 2005 May 1;74(2-3):287. Hossein Fatemi, S [corrected to Fatemi, S Hossein].
•   Fazel S, Lichtenstein P, Grann M, Goodwin GM, Langstrom N
  Bipolar disorder and violent crime: new evidence from population-based longitudinal studies and systematic review. Arch Gen Psychiatry. 2010 Sep;67(9):931-8. doi: 10.1001/archgenpsychiatry.2010.97.
•   Frye MA, Watzl J, Banakar S, O'Neill J, Mintz J, Davanzo P, Fischer J, Chirichigno JW, Ventura J, Elman S, Tsuang J, Walot I, Thomas MA
  Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in bipolar depression. Neuropsychopharmacology. 2007 Dec;32(12):2490-9. doi: 10.1038/sj.npp.1301387. Epub 2007 Apr 11.
•   Gass JT, Olive MF
  Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol. 2008 Jan 1;75(1):218-65. doi: 10.1016/j.bcp.2007.06.039. Epub 2007 Jun 30.
•   Gerner RH, Fairbanks L, Anderson GM, Young JG, Scheinin M, Linnoila M, Hare TA, Shaywitz BA, Cohen DJ
  CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls. Am J Psychiatry. 1984 Dec;141(12):1533-40. doi: 10.1176/ajp.141.12.1533.
•   Gibbons RD, Hur K, Brown CH, Mann JJ
  Gabapentin and suicide attempts. Pharmacoepidemiol Drug Saf. 2010 Dec;19(12):1241-7. doi: 10.1002/pds.2036. Epub 2010 Oct 4.
•   Godlewska BR, Yip SW, Near J, Goodwin GM, Cowen PJ
  Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy. Psychopharmacology (Berl). 2014 Jan;231(2):327-32. doi: 10.1007/s00213-013-3244-0. Epub 2013 Aug 17.
•   Goldberg JF, Garno JL, Leon AC, Kocsis JH, Portera L
  A history of substance abuse complicates remission from acute mania in bipolar disorder. J Clin Psychiatry. 1999 Nov;60(11):733-40. doi: 10.4088/jcp.v60n1103.
•   Gomez R, Behar KL, Watzl J, Weinzimer SA, Gulanski B, Sanacora G, Koretski J, Guidone E, Jiang L, Petrakis IL, Pittman B, Krystal JH, Mason GF
  Intravenous ethanol infusion decreases human cortical gamma-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla. Biol Psychiatry. 2012 Feb 1;71(3):239-46. doi: 10.1016/j.biopsych.2011.06.026. Epub 2011 Aug 19.
•   Grandjean EM, Berthet P, Ruffmann R, Leuenberger P
  Efficacy of oral long-term N-acetylcysteine in chronic bronchopulmonary disease: a meta-analysis of published double-blind, placebo-controlled clinical trials. Clin Ther. 2000 Feb;22(2):209-21. doi: 10.1016/S0149-2918(00)88479-9.
•   Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W, Pickering RP, Kaplan K
  Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry. 2004 Aug;61(8):807-16. doi: 10.1001/archpsyc.61.8.807.
•   Grant JE, Odlaug BL, Chamberlain SR, Potenza MN, Schreiber LR, Donahue CB, Kim SW
  A randomized, placebo-controlled trial of N-acetylcysteine plus imaginal desensitization for nicotine-dependent pathological gamblers. J Clin Psychiatry. 2014 Jan;75(1):39-45. doi: 10.4088/JCP.13m08411.
•   Grant JE, Odlaug BL, Kim SW
  A double-blind, placebo-controlled study of N-acetyl cysteine plus naltrexone for methamphetamine dependence. Eur Neuropsychopharmacol. 2010 Nov;20(11):823-8. doi: 10.1016/j.euroneuro.2010.06.018. Epub 2010 Jul 22.
•   Gray KM, Carpenter MJ, Baker NL, DeSantis SM, Kryway E, Hartwell KJ, McRae-Clark AL, Brady KT
  A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents. Am J Psychiatry. 2012 Aug;169(8):805-12. doi: 10.1176/appi.ajp.2012.12010055. Erratum In: Am J Psychiatry. 2012 Aug 1;169(8):869.
•   Hafeman DM, Chang KD, Garrett AS, Sanders EM, Phillips ML
  Effects of medication on neuroimaging findings in bipolar disorder: an updated review. Bipolar Disord. 2012 Jun;14(4):375-410. doi: 10.1111/j.1399-5618.2012.01023.x.
•   Hahn T, Dresler T, Ehlis AC, Plichta MM, Heinzel S, Polak T, Lesch KP, Breuer F, Jakob PM, Fallgatter AJ
  Neural response to reward anticipation is modulated by Gray's impulsivity. Neuroimage. 2009 Jul 15;46(4):1148-53. doi: 10.1016/j.neuroimage.2009.03.038. Epub 2009 Mar 25.
•   Harris AD, Puts NA, Edden RA
  Tissue correction for GABA-edited MRS: Considerations of voxel composition, tissue segmentation, and tissue relaxations. J Magn Reson Imaging. 2015 Nov;42(5):1431-40. doi: 10.1002/jmri.24903. Epub 2015 Jul 14. Erratum In: J Magn Reson Imaging. 2017 Jul;46(1):312.
•   Hassel S, Almeida JR, Kerr N, Nau S, Ladouceur CD, Fissell K, Kupfer DJ, Phillips ML
  Elevated striatal and decreased dorsolateral prefrontal cortical activity in response to emotional stimuli in euthymic bipolar disorder: no associations with psychotropic medication load. Bipolar Disord. 2008 Dec;10(8):916-27. doi: 10.1111/j.1399-5618.2008.00641.x.
•   Hermann D, Weber-Fahr W, Sartorius A, Hoerst M, Frischknecht U, Tunc-Skarka N, Perreau-Lenz S, Hansson AC, Krumm B, Kiefer F, Spanagel R, Mann K, Ende G, Sommer WH
  Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats. Biol Psychiatry. 2012 Jun 1;71(11):1015-21. doi: 10.1016/j.biopsych.2011.07.034. Epub 2011 Sep 10.
•   Hoblyn JC, Balt SL, Woodard SA, Brooks JO 3rd
  Substance use disorders as risk factors for psychiatric hospitalization in bipolar disorder. Psychiatr Serv. 2009 Jan;60(1):50-5. doi: 10.1176/ps.2009.60.1.50.
•   Hoerst M, Weber-Fahr W, Tunc-Skarka N, Ruf M, Bohus M, Schmahl C, Ende G
  Correlation of glutamate levels in the anterior cingulate cortex with self-reported impulsivity in patients with borderline personality disorder and healthy controls. Arch Gen Psychiatry. 2010 Sep;67(9):946-54. doi: 10.1001/archgenpsychiatry.2010.93. Epub 2010 Jul 5.
•   Holdiness MR
  Clinical pharmacokinetics of N-acetylcysteine. Clin Pharmacokinet. 1991 Feb;20(2):123-34. doi: 10.2165/00003088-199120020-00004.
•   Horiuchi Y, Nakayama J, Ishiguro H, Ohtsuki T, Detera-Wadleigh SD, Toyota T, Yamada K, Nankai M, Shibuya H, Yoshikawa T, Arinami T
  Possible association between a haplotype of the GABA-A receptor alpha 1 subunit gene (GABRA1) and mood disorders. Biol Psychiatry. 2004 Jan 1;55(1):40-5. doi: 10.1016/s0006-3223(03)00689-9.
•   Jones AL, Jarvie DR, Simpson D, Hayes PC, Prescott LF
  Pharmacokinetics of N-acetylcysteine are altered in patients with chronic liver disease. Aliment Pharmacol Ther. 1997 Aug;11(4):787-91. doi: 10.1046/j.1365-2036.1997.00209.x.
•   Juenke JM, Wienhoff KA, Anderson BL, McMillin GA, Johnson-Davis KL
  Performance characteristics of the ARK diagnostics gabapentin immunoassay. Ther Drug Monit. 2011 Aug;33(4):398-401. doi: 10.1097/FTD.0b013e318220bb65.
•   Kaladjian A, Jeanningros R, Azorin JM, Nazarian B, Roth M, Mazzola-Pomietto P
  Reduced brain activation in euthymic bipolar patients during response inhibition: an event-related fMRI study. Psychiatry Res. 2009 Jul 15;173(1):45-51. doi: 10.1016/j.pscychresns.2008.08.003. Epub 2009 May 12.
•   Kalivas PW, O'Brien C
  Drug addiction as a pathology of staged neuroplasticity. Neuropsychopharmacology. 2008 Jan;33(1):166-80. doi: 10.1038/sj.npp.1301564. Epub 2007 Sep 5.
•   Kalivas PW
  The glutamate homeostasis hypothesis of addiction. Nat Rev Neurosci. 2009 Aug;10(8):561-72. doi: 10.1038/nrn2515. Epub 2009 Jul 1.
•   Kaufman RE, Ostacher MJ, Marks EH, Simon NM, Sachs GS, Jensen JE, Renshaw PF, Pollack MH
  Brain GABA levels in patients with bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Apr 30;33(3):427-34. doi: 10.1016/j.pnpbp.2008.12.025. Epub 2009 Jan 10.
•   Knackstedt LA, LaRowe S, Mardikian P, Malcolm R, Upadhyaya H, Hedden S, Markou A, Kalivas PW
  The role of cystine-glutamate exchange in nicotine dependence in rats and humans. Biol Psychiatry. 2009 May 15;65(10):841-5. doi: 10.1016/j.biopsych.2008.10.040. Epub 2008 Dec 21.
•   Koob GF, Volkow ND
  Neurocircuitry of addiction. Neuropsychopharmacology. 2010 Jan;35(1):217-38. doi: 10.1038/npp.2009.110. Erratum In: Neuropsychopharmacology. 2010 Mar;35(4):1051.
•   Krystal JH, Staley J, Mason G, Petrakis IL, Kaufman J, Harris RA, Gelernter J, Lappalainen J
  Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Arch Gen Psychiatry. 2006 Sep;63(9):957-68. doi: 10.1001/archpsyc.63.9.957.
•   Kuzniecky R, Ho S, Pan J, Martin R, Gilliam F, Faught E, Hetherington H
  Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults. Neurology. 2002 Feb 12;58(3):368-72. doi: 10.1212/wnl.58.3.368.
•   LaRowe SD, Kalivas PW, Nicholas JS, Randall PK, Mardikian PN, Malcolm RJ
  A double-blind placebo-controlled trial of N-acetylcysteine in the treatment of cocaine dependence. Am J Addict. 2013 Sep-Oct;22(5):443-52. doi: 10.1111/j.1521-0391.2013.12034.x. Epub 2013 May 15.
•   LaRowe SD, Myrick H, Hedden S, Mardikian P, Saladin M, McRae A, Brady K, Kalivas PW, Malcolm R
  Is cocaine desire reduced by N-acetylcysteine? Am J Psychiatry. 2007 Jul;164(7):1115-7. doi: 10.1176/ajp.2007.164.7.1115.
•   Lawrence NS, Williams AM, Surguladze S, Giampietro V, Brammer MJ, Andrew C, Frangou S, Ecker C, Phillips ML
  Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression. Biol Psychiatry. 2004 Mar 15;55(6):578-87. doi: 10.1016/j.biopsych.2003.11.017.
•   Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT, McMahon FJ, Schork NJ, Nurnberger JI Jr, Niculescu AB 3rd
  Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):155-81. doi: 10.1002/ajmg.b.30887.
•   Li CS, Luo X, Yan P, Bergquist K, Sinha R
  Altered impulse control in alcohol dependence: neural measures of stop signal performance. Alcohol Clin Exp Res. 2009 Apr;33(4):740-50. doi: 10.1111/j.1530-0277.2008.00891.x. Epub 2009 Jan 21.
•   Luijten M, Machielsen MW, Veltman DJ, Hester R, de Haan L, Franken IH
  Systematic review of ERP and fMRI studies investigating inhibitory control and error processing in people with substance dependence and behavioural addictions. J Psychiatry Neurosci. 2014 May;39(3):149-69. doi: 10.1503/jpn.130052.
•   MacKinnon DP, Fairchild AJ, Fritz MS
  Mediation analysis. Annu Rev Psychol. 2007;58:593-614. doi: 10.1146/annurev.psych.58.110405.085542.
•   Madayag A, Lobner D, Kau KS, Mantsch JR, Abdulhameed O, Hearing M, Grier MD, Baker DA
  Repeated N-acetylcysteine administration alters plasticity-dependent effects of cocaine. J Neurosci. 2007 Dec 19;27(51):13968-76. doi: 10.1523/JNEUROSCI.2808-07.2007.
•   Maeng S, Zarate CA Jr, Du J, Schloesser RJ, McCammon J, Chen G, Manji HK
  Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors. Biol Psychiatry. 2008 Feb 15;63(4):349-52. doi: 10.1016/j.biopsych.2007.05.028. Epub 2007 Jul 23.
•   Mason BJ, Quello S, Goodell V, Shadan F, Kyle M, Begovic A
  Gabapentin treatment for alcohol dependence: a randomized clinical trial. JAMA Intern Med. 2014 Jan;174(1):70-7. doi: 10.1001/jamainternmed.2013.11950.
•   Mason GF, Petrakis IL, de Graaf RA, Gueorguieva R, Guidone E, Coric V, Epperson CN, Rothman DL, Krystal JH
  Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking. Biol Psychiatry. 2006 Jan 1;59(1):85-93. doi: 10.1016/j.biopsych.2005.06.009. Epub 2005 Nov 14.
•   Massat I, Souery D, Del-Favero J, Oruc L, Noethen MM, Blackwood D, Thomson M, Muir W, Papadimitriou GN, Dikeos DG, Kaneva R, Serretti A, Lilli R, Smeraldi E, Jakovljevic M, Folnegovic V, Rietschel M, Milanova V, Valente F, Van Broeckhoven C, Mendlewicz J
  Excess of allele1 for alpha3 subunit GABA receptor gene (GABRA3) in bipolar patients: a multicentric association study. Mol Psychiatry. 2002;7(2):201-7. doi: 10.1038/sj.mp.4000953.
•   McFarland K, Kalivas PW
  The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior. J Neurosci. 2001 Nov 1;21(21):8655-63. doi: 10.1523/JNEUROSCI.21-21-08655.2001.
•   Michael N, Erfurth A, Ohrmann P, Gossling M, Arolt V, Heindel W, Pfleiderer B
  Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex. Psychopharmacology (Berl). 2003 Jul;168(3):344-6. doi: 10.1007/s00213-003-1440-z. Epub 2003 Apr 9.
•   Michael N, Erfurth A, Pfleiderer B
  Elevated metabolites within dorsolateral prefrontal cortex in rapid cycling bipolar disorder. Psychiatry Res. 2009 Apr 30;172(1):78-81. doi: 10.1016/j.pscychresns.2009.01.002. Epub 2009 Feb 23.
•   Mitchell JM, Fields HL, D'Esposito M, Boettiger CA
  Impulsive responding in alcoholics. Alcohol Clin Exp Res. 2005 Dec;29(12):2158-69. doi: 10.1097/01.alc.0000191755.63639.4a.
•   Mon A, Durazzo TC, Meyerhoff DJ
  Glutamate, GABA, and other cortical metabolite concentrations during early abstinence from alcohol and their associations with neurocognitive changes. Drug Alcohol Depend. 2012 Sep 1;125(1-2):27-36. doi: 10.1016/j.drugalcdep.2012.03.012. Epub 2012 Apr 12.
•   Montgomery SA, Asberg M
  A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979 Apr;134:382-9. doi: 10.1192/bjp.134.4.382.
•   Mousavi SG, Sharbafchi MR, Salehi M, Peykanpour M, Karimian Sichani N, Maracy M
  The efficacy of N-acetylcysteine in the treatment of methamphetamine dependence: a double-blind controlled, crossover study. Arch Iran Med. 2015 Jan;18(1):28-33.
•   Mullins PG, Chen H, Xu J, Caprihan A, Gasparovic C
  Comparative reliability of proton spectroscopy techniques designed to improve detection of J-coupled metabolites. Magn Reson Med. 2008 Oct;60(4):964-9. doi: 10.1002/mrm.21696.
•   Murali AR, Attar BM, Katz A, Kotwal V, Clarke PM
  Utility of Platelet Count for Predicting Cirrhosis in Alcoholic Liver Disease: Model for Identifying Cirrhosis in a US Population. J Gen Intern Med. 2015 Aug;30(8):1112-7. doi: 10.1007/s11606-015-3238-1. Epub 2015 Feb 21.
•   Murphy ER, Fernando AB, Urcelay GP, Robinson ES, Mar AC, Theobald DE, Dalley JW, Robbins TW
  Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex. Psychopharmacology (Berl). 2012 Jan;219(2):401-10. doi: 10.1007/s00213-011-2572-1. Epub 2011 Nov 19.
•   Myrick H, Anton RF, Li X, Henderson S, Drobes D, Voronin K, George MS
  Differential brain activity in alcoholics and social drinkers to alcohol cues: relationship to craving. Neuropsychopharmacology. 2004 Feb;29(2):393-402. doi: 10.1038/sj.npp.1300295.
•   Myrick H, Anton RF, Li X, Henderson S, Randall PK, Voronin K
  Effect of naltrexone and ondansetron on alcohol cue-induced activation of the ventral striatum in alcohol-dependent people. Arch Gen Psychiatry. 2008 Apr;65(4):466-75. doi: 10.1001/archpsyc.65.4.466.
•   Myrick H, Li X, Randall PK, Henderson S, Voronin K, Anton RF
  The effect of aripiprazole on cue-induced brain activation and drinking parameters in alcoholics. J Clin Psychopharmacol. 2010 Aug;30(4):365-72. doi: 10.1097/JCP.0b013e3181e75cff.
•   Myrick H, Malcolm R, Randall PK, Boyle E, Anton RF, Becker HC, Randall CL
  A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal. Alcohol Clin Exp Res. 2009 Sep;33(9):1582-8. doi: 10.1111/j.1530-0277.2009.00986.x. Epub 2009 May 26.
•   Nery FG, Stanley JA, Chen HH, Hatch JP, Nicoletti MA, Monkul ES, Lafer B, Soares JC
  Bipolar disorder comorbid with alcoholism: a 1H magnetic resonance spectroscopy study. J Psychiatr Res. 2010 Apr;44(5):278-85. doi: 10.1016/j.jpsychires.2009.09.006. Epub 2009 Oct 8.
•   Niciu MJ, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Ballard ED, Brutsche NE, Furey ML, Zarate CA Jr
  Riluzole likely lacks antidepressant efficacy in ketamine non-responders. J Psychiatr Res. 2014 Nov;58:197-9. doi: 10.1016/j.jpsychires.2014.07.022. Epub 2014 Aug 6. No abstract available.
•   O'Gorman RL, Michels L, Edden RA, Murdoch JB, Martin E
  In vivo detection of GABA and glutamate with MEGA-PRESS: reproducibility and gender effects. J Magn Reson Imaging. 2011 May;33(5):1262-7. doi: 10.1002/jmri.22520.
•   Ogg RJ, Zou P, Allen DN, Hutchins SB, Dutkiewicz RM, Mulhern RK
  Neural correlates of a clinical continuous performance test. Magn Reson Imaging. 2008 May;26(4):504-12. doi: 10.1016/j.mri.2007.09.004. Epub 2008 Feb 20.
•   Oldfield RC
  The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971 Mar;9(1):97-113. doi: 10.1016/0028-3932(71)90067-4. No abstract available.
•   Ongur D, Jensen JE, Prescot AP, Stork C, Lundy M, Cohen BM, Renshaw PF
  Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania. Biol Psychiatry. 2008 Oct 15;64(8):718-726. doi: 10.1016/j.biopsych.2008.05.014. Epub 2008 Jul 7.
•   Oquendo MA, Currier D, Liu SM, Hasin DS, Grant BF, Blanco C
  Increased risk for suicidal behavior in comorbid bipolar disorder and alcohol use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). J Clin Psychiatry. 2010 Jul;71(7):902-9. doi: 10.4088/JCP.09m05198gry.
•   Otani K, Ujike H, Tanaka Y, Morita Y, Katsu T, Nomura A, Uchida N, Hamamura T, Fujiwara Y, Kuroda S
  The GABA type A receptor alpha5 subunit gene is associated with bipolar I disorder. Neurosci Lett. 2005 Jun 10-17;381(1-2):108-13. doi: 10.1016/j.neulet.2005.02.010. Epub 2005 Feb 25.
•   Pattij T, Vanderschuren LJ
  The neuropharmacology of impulsive behaviour. Trends Pharmacol Sci. 2008 Apr;29(4):192-9. doi: 10.1016/j.tips.2008.01.002. Epub 2008 Mar 4.
•   Patton JH, Stanford MS, Barratt ES
  Factor structure of the Barratt impulsiveness scale. J Clin Psychol. 1995 Nov;51(6):768-74. doi: 10.1002/1097-4679(199511)51:63.0.co;2-1.
•   Peng PW, Wijeysundera DN, Li CC
  Use of gabapentin for perioperative pain control -- a meta-analysis. Pain Res Manag. 2007 Summer;12(2):85-92. doi: 10.1155/2007/840572.
•   Perlis RH, Dennehy EB, Miklowitz DJ, Delbello MP, Ostacher M, Calabrese JR, Ametrano RM, Wisniewski SR, Bowden CL, Thase ME, Nierenberg AA, Sachs G
  Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study. Bipolar Disord. 2009 Jun;11(4):391-400. doi: 10.1111/j.1399-5618.2009.00686.x.
•   Petroff OA, Hyder F, Rothman DL, Mattson RH
  Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients. Epilepsia. 2000 Jun;41(6):675-80. doi: 10.1111/j.1528-1157.2000.tb00227.x.
•   Petroff OA, Rothman DL, Behar KL, Lamoureux D, Mattson RH
  The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy. Ann Neurol. 1996 Jan;39(1):95-9. doi: 10.1002/ana.410390114.
•   Petty F, Kramer GL, Dunnam D, Rush AJ
  Plasma GABA in mood disorders. Psychopharmacol Bull. 1990;26(2):157-61.
•   Phan KL, Fitzgerald DA, Cortese BM, Seraji-Bozorgzad N, Tancer ME, Moore GJ
  Anterior cingulate neurochemistry in social anxiety disorder: 1H-MRS at 4 Tesla. Neuroreport. 2005 Feb 8;16(2):183-6. doi: 10.1097/00001756-200502080-00024.
•   Phillips ML, Travis MJ, Fagiolini A, Kupfer DJ
  Medication effects in neuroimaging studies of bipolar disorder. Am J Psychiatry. 2008 Mar;165(3):313-20. doi: 10.1176/appi.ajp.2007.07071066. Epub 2008 Feb 1.
•   Post RM, Denicoff KD, Leverich GS, Altshuler LL, Frye MA, Suppes TM, Rush AJ, Keck PE Jr, McElroy SL, Luckenbaugh DA, Pollio C, Kupka R, Nolen WA
  Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart method. J Clin Psychiatry. 2003 Jun;64(6):680-90; quiz 738-9. doi: 10.4088/jcp.v64n0610.
•   Prado E, Maes M, Piccoli LG, Baracat M, Barbosa DS, Franco O, Dodd S, Berk M, Vargas Nunes SO
  N-acetylcysteine for therapy-resistant tobacco use disorder: a pilot study. Redox Rep. 2015 Sep;20(5):215-22. doi: 10.1179/1351000215Y.0000000004. Epub 2015 Mar 2.
•   Prescot AP, Locatelli AE, Renshaw PF, Yurgelun-Todd DA
  Neurochemical alterations in adolescent chronic marijuana smokers: a proton MRS study. Neuroimage. 2011 Jul 1;57(1):69-75. doi: 10.1016/j.neuroimage.2011.02.044. Epub 2011 Feb 22.
•   Prescot AP, Renshaw PF, Yurgelun-Todd DA
  gamma-Amino butyric acid and glutamate abnormalities in adolescent chronic marijuana smokers. Drug Alcohol Depend. 2013 May 1;129(3):232-9. doi: 10.1016/j.drugalcdep.2013.02.028. Epub 2013 Mar 21.
•   Prescot AP, Renshaw PF
  Two-dimensional J-resolved proton MR spectroscopy and prior knowledge fitting (ProFit) in the frontal and parietal lobes of healthy volunteers: assessment of metabolite discrimination and general reproducibility. J Magn Reson Imaging. 2013 Mar;37(3):642-51. doi: 10.1002/jmri.23848. Epub 2012 Oct 10.
•   Prisciandaro JJ, Brown DG, Brady KT, Tolliver BK
  Comorbid anxiety disorders and baseline medication regimens predict clinical outcomes in individuals with co-occurring bipolar disorder and alcohol dependence: Results of a randomized controlled trial. Psychiatry Res. 2011 Aug 15;188(3):361-5. doi: 10.1016/j.psychres.2011.04.030. Epub 2011 Jun 8. Erratum In: Psychiatry Res. 2021 Jan;295:112904.
•   Prisciandaro JJ, DeSantis SM, Chiuzan C, Brown DG, Brady KT, Tolliver BK
  Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate. Alcohol Clin Exp Res. 2012 Mar;36(3):490-6. doi: 10.1111/j.1530-0277.2011.01645.x. Epub 2011 Sep 20.
•   Prisciandaro JJ, Joseph JE, Myrick H, McRae-Clark AL, Henderson S, Pfeifer J, Brady KT
  The relationship between years of cocaine use and brain activation to cocaine and response inhibition cues. Addiction. 2014 Dec;109(12):2062-70. doi: 10.1111/add.12666. Epub 2014 Jul 21.
•   Prisciandaro JJ, Myrick H, Henderson S, McRae-Clark AL, Brady KT
  Prospective associations between brain activation to cocaine and no-go cues and cocaine relapse. Drug Alcohol Depend. 2013 Jul 1;131(1-2):44-9. doi: 10.1016/j.drugalcdep.2013.04.008. Epub 2013 May 15.
•   Prisciandaro JJ, Rembold J, Brown DG, Brady KT, Tolliver BK
  Predictors of clinical trial dropout in individuals with co-occurring bipolar disorder and alcohol dependence. Drug Alcohol Depend. 2011 Nov 1;118(2-3):493-6. doi: 10.1016/j.drugalcdep.2011.03.029. Epub 2011 May 6.
•   Prisciandaro JJ, Schacht JP, Prescot AP, Renshaw PF, Brown TR, Anton RF
  Associations Between Recent Heavy Drinking and Dorsal Anterior Cingulate N-Acetylaspartate and Glutamate Concentrations in Non-Treatment-Seeking Individuals with Alcohol Dependence. Alcohol Clin Exp Res. 2016 Mar;40(3):491-6. doi: 10.1111/acer.12977. Epub 2016 Feb 8.
•   Prisciandaro JJ, Tolliver BK
  Evidence for the continuous latent structure of mania and depression in out-patients with bipolar disorder: results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Psychol Med. 2015;45(12):2595-603. doi: 10.1017/S0033291715000513. Epub 2015 Apr 17.
•   Provencher SW
  Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med. 1993 Dec;30(6):672-9. doi: 10.1002/mrm.1910300604.
•   Puts NA, Edden RA
  In vivo magnetic resonance spectroscopy of GABA: a methodological review. Prog Nucl Magn Reson Spectrosc. 2012 Jan;60:29-41. doi: 10.1016/j.pnmrs.2011.06.001. Epub 2011 Jun 12. No abstract available.
•   Regier DA, Farmer ME, Rae DS, Locke BZ, Keith SJ, Judd LL, Goodwin FK
  Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAMA. 1990 Nov 21;264(19):2511-8.
•   Robinson ES, Eagle DM, Economidou D, Theobald DE, Mar AC, Murphy ER, Robbins TW, Dalley JW
  Behavioural characterisation of high impulsivity on the 5-choice serial reaction time task: specific deficits in 'waiting' versus 'stopping'. Behav Brain Res. 2009 Jan 23;196(2):310-6. doi: 10.1016/j.bbr.2008.09.021. Epub 2008 Oct 2.
•   Rose MA, Kam PC
  Gabapentin: pharmacology and its use in pain management. Anaesthesia. 2002 May;57(5):451-62. doi: 10.1046/j.0003-2409.2001.02399.x.
•   Rosner S, Hackl-Herrwerth A, Leucht S, Lehert P, Vecchi S, Soyka M
  Acamprosate for alcohol dependence. Cochrane Database Syst Rev. 2010 Sep 8;(9):CD004332. doi: 10.1002/14651858.CD004332.pub2.
•   Rowland LM, Bustillo JR, Mullins PG, Jung RE, Lenroot R, Landgraf E, Barrow R, Yeo R, Lauriello J, Brooks WM
  Effects of ketamine on anterior cingulate glutamate metabolism in healthy humans: a 4-T proton MRS study. Am J Psychiatry. 2005 Feb;162(2):394-6. doi: 10.1176/appi.ajp.162.2.394.
•   Rubio G, Jimenez M, Rodriguez-Jimenez R, Martinez I, Avila C, Ferre F, Jimenez-Arriero MA, Ponce G, Palomo T
  The role of behavioral impulsivity in the development of alcohol dependence: a 4-year follow-up study. Alcohol Clin Exp Res. 2008 Sep;32(9):1681-7. doi: 10.1111/j.1530-0277.2008.00746.x. Epub 2008 Jul 9.
•   Salloum IM, Cornelius JR, Daley DC, Kirisci L, Himmelhoch JM, Thase ME
  Efficacy of valproate maintenance in patients with bipolar disorder and alcoholism: a double-blind placebo-controlled study. Arch Gen Psychiatry. 2005 Jan;62(1):37-45. doi: 10.1001/archpsyc.62.1.37.
•   Sanacora G, Zarate CA, Krystal JH, Manji HK
  Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov. 2008 May;7(5):426-37. doi: 10.1038/nrd2462.
•   Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M
  Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption--II. Addiction. 1993 Jun;88(6):791-804. doi: 10.1111/j.1360-0443.1993.tb02093.x.
•   Schacht JP, Anton RF, Myrick H
  Functional neuroimaging studies of alcohol cue reactivity: a quantitative meta-analysis and systematic review. Addict Biol. 2013 Jan;18(1):121-33. doi: 10.1111/j.1369-1600.2012.00464.x. Epub 2012 May 10.
•   Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H
  Stability of fMRI striatal response to alcohol cues: a hierarchical linear modeling approach. Neuroimage. 2011 May 1;56(1):61-8. doi: 10.1016/j.neuroimage.2011.02.004. Epub 2011 Feb 18.
•   Schmaal L, Veltman DJ, Nederveen A, van den Brink W, Goudriaan AE
  N-acetylcysteine normalizes glutamate levels in cocaine-dependent patients: a randomized crossover magnetic resonance spectroscopy study. Neuropsychopharmacology. 2012 Aug;37(9):2143-52. doi: 10.1038/npp.2012.66. Epub 2012 May 2.
•   Schulte RF, Boesiger P
  ProFit: two-dimensional prior-knowledge fitting of J-resolved spectra. NMR Biomed. 2006 Apr;19(2):255-63. doi: 10.1002/nbm.1026.
•   Sills GJ
  The mechanisms of action of gabapentin and pregabalin. Curr Opin Pharmacol. 2006 Feb;6(1):108-13. doi: 10.1016/j.coph.2005.11.003. Epub 2005 Dec 22.
•   Silveri MM, Sneider JT, Crowley DJ, Covell MJ, Acharya D, Rosso IM, Jensen JE
  Frontal lobe gamma-aminobutyric acid levels during adolescence: associations with impulsivity and response inhibition. Biol Psychiatry. 2013 Aug 15;74(4):296-304. doi: 10.1016/j.biopsych.2013.01.033. Epub 2013 Mar 14.
•   Simon JJ, Walther S, Fiebach CJ, Friederich HC, Stippich C, Weisbrod M, Kaiser S
  Neural reward processing is modulated by approach- and avoidance-related personality traits. Neuroimage. 2010 Jan 15;49(2):1868-74. doi: 10.1016/j.neuroimage.2009.09.016. Epub 2009 Sep 18.
•   Simon NM, Otto MW, Wisniewski SR, Fossey M, Sagduyu K, Frank E, Sachs GS, Nierenberg AA, Thase ME, Pollack MH
  Anxiety disorder comorbidity in bipolar disorder patients: data from the first 500 participants in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Am J Psychiatry. 2004 Dec;161(12):2222-9. doi: 10.1176/appi.ajp.161.12.2222.
•   Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TE, Johansen-Berg H, Bannister PR, De Luca M, Drobnjak I, Flitney DE, Niazy RK, Saunders J, Vickers J, Zhang Y, De Stefano N, Brady JM, Matthews PM
  Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage. 2004;23 Suppl 1:S208-19. doi: 10.1016/j.neuroimage.2004.07.051.
•   Sobell LC, Brown J, Leo GI, Sobell MB
  The reliability of the Alcohol Timeline Followback when administered by telephone and by computer. Drug Alcohol Depend. 1996 Sep;42(1):49-54. doi: 10.1016/0376-8716(96)01263-x.
•   Soeiro-de-Souza MG, Henning A, Machado-Vieira R, Moreno RA, Pastorello BF, da Costa Leite C, Vallada H, Otaduy MC
  Anterior cingulate Glutamate-Glutamine cycle metabolites are altered in euthymic bipolar I disorder. Eur Neuropsychopharmacol. 2015 Dec;25(12):2221-9. doi: 10.1016/j.euroneuro.2015.09.020. Epub 2015 Oct 9.
•   Soeiro-de-Souza MG, Salvadore G, Moreno RA, Otaduy MC, Chaim KT, Gattaz WF, Zarate CA Jr, Machado-Vieira R
  Bcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder. Neuropsychopharmacology. 2013 Feb;38(3):468-75. doi: 10.1038/npp.2012.203. Epub 2012 Oct 17.
•   Stone JM, Dietrich C, Edden R, Mehta MA, De Simoni S, Reed LJ, Krystal JH, Nutt D, Barker GJ
  Ketamine effects on brain GABA and glutamate levels with 1H-MRS: relationship to ketamine-induced psychopathology. Mol Psychiatry. 2012 Jul;17(7):664-5. doi: 10.1038/mp.2011.171. Epub 2012 Jan 3. No abstract available.
•   Sullivan JT, Sykora K, Schneiderman J, Naranjo CA, Sellers EM
  Assessment of alcohol withdrawal: the revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar). Br J Addict. 1989 Nov;84(11):1353-7. doi: 10.1111/j.1360-0443.1989.tb00737.x.
•   Swann AC, Lijffijt M, Lane SD, Steinberg JL, Moeller FG
  Increased trait-like impulsivity and course of illness in bipolar disorder. Bipolar Disord. 2009 May;11(3):280-8. doi: 10.1111/j.1399-5618.2009.00678.x.
•   Swann AC, Lijffijt M, Lane SD, Steinberg JL, Moeller FG
  Severity of bipolar disorder is associated with impairment of response inhibition. J Affect Disord. 2009 Jul;116(1-2):30-6. doi: 10.1016/j.jad.2008.10.022. Epub 2008 Nov 26.
•   Swann AC, Pazzaglia P, Nicholls A, Dougherty DM, Moeller FG
  Impulsivity and phase of illness in bipolar disorder. J Affect Disord. 2003 Jan;73(1-2):105-11. doi: 10.1016/s0165-0327(02)00328-2.
•   Swann AC
  The strong relationship between bipolar and substance-use disorder. Ann N Y Acad Sci. 2010 Feb;1187:276-93. doi: 10.1111/j.1749-6632.2009.05146.x.
•   Swick D, Ashley V, Turken U
  Are the neural correlates of stopping and not going identical? Quantitative meta-analysis of two response inhibition tasks. Neuroimage. 2011 Jun 1;56(3):1655-65. doi: 10.1016/j.neuroimage.2011.02.070. Epub 2011 Mar 3.
•   Thoma R, Mullins P, Ruhl D, Monnig M, Yeo RA, Caprihan A, Bogenschutz M, Lysne P, Tonigan S, Kalyanam R, Gasparovic C
  Perturbation of the glutamate-glutamine system in alcohol dependence and remission. Neuropsychopharmacology. 2011 Jun;36(7):1359-65. doi: 10.1038/npp.2011.20. Epub 2011 Mar 9. Erratum In: Neuropsychopharmacology. 2012 Apr;37(5):1321.
•   Tolliver BK, Desantis SM, Brown DG, Prisciandaro JJ, Brady KT
  A randomized, double-blind, placebo-controlled clinical trial of acamprosate in alcohol-dependent individuals with bipolar disorder: a preliminary report. Bipolar Disord. 2012 Feb;14(1):54-63. doi: 10.1111/j.1399-5618.2011.00973.x.
•   Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L, Adams LJ, Vengeliene V, Spanagel R, Zhang Y, Shen J, George DT, Hommer D, Heilig M
  Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Arch Gen Psychiatry. 2010 Oct;67(10):1069-77. doi: 10.1001/archgenpsychiatry.2010.125.
•   van Veenendaal TM, IJff DM, Aldenkamp AP, Hofman PA, Vlooswijk MC, Rouhl RP, de Louw AJ, Backes WH, Jansen JF
  Metabolic and functional MR biomarkers of antiepileptic drug effectiveness: A review. Neurosci Biobehav Rev. 2015 Dec;59:92-9. doi: 10.1016/j.neubiorev.2015.10.004. Epub 2015 Oct 22.
•   Wang PW, Sailasuta N, Chandler RA, Ketter TA
  Magnetic resonance spectroscopic measurement of cerebral gamma-aminobutyric acid concentrations in patients with bipolar disorders. Acta Neuropsychiatr. 2006 Apr;18(2):120-6. doi: 10.1111/j.1601-5215.2006.00132.x.
•   Wilk J, West JC, Rae DS, Regier DA
  Relationship of comorbid substance and alcohol use disorders to disability among patients in routine psychiatric practice. Am J Addict. 2006 Mar-Apr;15(2):180-5. doi: 10.1080/10550490500528799.
•   Wrase J, Schlagenhauf F, Kienast T, Wustenberg T, Bermpohl F, Kahnt T, Beck A, Strohle A, Juckel G, Knutson B, Heinz A
  Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics. Neuroimage. 2007 Apr 1;35(2):787-94. doi: 10.1016/j.neuroimage.2006.11.043. Epub 2007 Feb 8.
•   Yoon YH, Chen CM, Yi HY, Moss HB
  Effect of comorbid alcohol and drug use disorders on premature death among unipolar and bipolar disorder decedents in the United States, 1999 to 2006. Compr Psychiatry. 2011 Sep-Oct;52(5):453-64. doi: 10.1016/j.comppsych.2010.10.005. Epub 2010 Dec 13.
•   Young RC, Biggs JT, Ziegler VE, Meyer DA
  A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry. 1978 Nov;133:429-35. doi: 10.1192/bjp.133.5.429.
•   Yuksel C, Ongur D
  Magnetic resonance spectroscopy studies of glutamate-related abnormalities in mood disorders. Biol Psychiatry. 2010 Nov 1;68(9):785-94. doi: 10.1016/j.biopsych.2010.06.016. Epub 2010 Aug 21.
•   Zand L, McKian KP, Qian Q
  Gabapentin toxicity in patients with chronic kidney disease: a preventable cause of morbidity. Am J Med. 2010 Apr;123(4):367-73. doi: 10.1016/j.amjmed.2009.09.030. Erratum In: Am J Med. 2011 Oct;124(10):e9.

Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics

Details for clinical trial NCT03220776