Asthma — Exercise Induced Bronchoconstriction and Field Tests
Citation(s)
Anderson SD, Argyros GJ, Magnussen H, Holzer K Provocation by eucapnic voluntary hyperpnoea to identify exercise induced bronchoconstriction. Br J Sports Med. 2001 Oct;35(5):344-7. Review.
Anderson SD, Kippelen P Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes. J Allergy Clin Immunol. 2008 Aug;122(2):225-35; quiz 236-7. doi: 10.1016/j.jaci.2008.05.001. Epub 2008 Jun 12. Review.
Anderson SD How does exercise cause asthma attacks? Curr Opin Allergy Clin Immunol. 2006 Feb;6(1):37-42. Review.
Ansley L, Kippelen P, Dickinson J, Hull JH Misdiagnosis of exercise-induced bronchoconstriction in professional soccer players. Allergy. 2012 Mar;67(3):390-5. doi: 10.1111/j.1398-9995.2011.02762.x. Epub 2011 Dec 17.
Brannan JD, Koskela H, Anderson SD Monitoring asthma therapy using indirect bronchial provocation tests. Clin Respir J. 2007 Jul;1(1):3-15. doi: 10.1111/j.1752-699X.2007.00004.x. Review.
Fitch KD An overview of asthma and airway hyper-responsiveness in Olympic athletes. Br J Sports Med. 2012 May;46(6):413-6. doi: 10.1136/bjsports-2011-090814. Epub 2012 Jan 8. Review.
Heir T, Larsen S The influence of training intensity, airway infections and environmental conditions on seasonal variations in bronchial responsiveness in cross-country skiers. Scand J Med Sci Sports. 1995 Jun;5(3):152-9.
Hull JH, Ansley L, Price OJ, Dickinson JW, Bonini M Eucapnic Voluntary Hyperpnea: Gold Standard for Diagnosing Exercise-Induced Bronchoconstriction in Athletes? Sports Med. 2016 Aug;46(8):1083-93. doi: 10.1007/s40279-016-0491-3. Review.
Matui P, Wyatt JC, Pinnock H, Sheikh A, McLean S Computer decision support systems for asthma: a systematic review. NPJ Prim Care Respir Med. 2014 May 20;24:14005. doi: 10.1038/npjpcrm.2014.5. Review.
Norqvist J, Eriksson L, Söderström L, Lindberg A, Stenfors N Self-reported physician-diagnosed asthma among Swedish adolescent, adult and former elite endurance athletes. J Asthma. 2015;52(10):1046-53. doi: 10.3109/02770903.2015.1038389. Epub 2015 Aug 18.
Rundell KW, Anderson SD, Spiering BA, Judelson DA Field exercise vs laboratory eucapnic voluntary hyperventilation to identify airway hyperresponsiveness in elite cold weather athletes. Chest. 2004 Mar;125(3):909-15.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
