Asthma — Animal Allergy in Korean Veterinary Researcher
Citation(s)
Blair A, Hayes HM Jr Cancer and other causes of death among U.S. veterinarians, 1966-1977. Int J Cancer. 1980 Feb 15;25(2):181-5.
Elbers AR, Blaauw PJ, de Vries M, van Gulick PJ, Smithuis OL, Gerrits RP, Tielen MJ Veterinary practice and occupational health. An epidemiological study of several professional groups of Dutch veterinarians. I. General physical examination and prevalence of allergy, lung function disorders, and bronchial hyperreactivity. Vet Q. 1996 Dec;18(4):127-31.
Moghtaderi M, Farjadian S, Abbaszadeh Hasiri M Animal allergen sensitization in veterinarians and laboratory animal workers. Occup Med (Lond). 2014 Oct;64(7):516-20. doi: 10.1093/occmed/kqu097.
Park YB, Mo EK, Lee JY, Kim JH, Kim CH, Hyun IG, Choi JH Association between pet ownership and the sensitization to pet allergens in adults with various allergic diseases. Allergy Asthma Immunol Res. 2013 Sep;5(5):295-300. doi: 10.4168/aair.2013.5.5.295.
Samadi S, Wouters IM, Heederik DJ A review of bio-aerosol exposures and associated health effects in veterinary practice. Ann Agric Environ Med. 2013;20(2):206-21. Review.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
