Artificial Intelligence — Study on the Prognostic Prediction Model of Patients With Acute Intracerebral Hemorrhage by Artificial Intelligence
Citation(s)
Fu F, Sun S, Liu L, Gu H, Su Y, Li Y Iodine Sign as a Novel Predictor of Hematoma Expansion and Poor Outcomes in Primary Intracerebral Hemorrhage Patients. Stroke. 2018 Sep;49(9):2074-2080. doi: 10.1161/STROKEAHA.118.022017.
Guo R, Zhang R, Liu R, Liu Y, Li H, Ma L, He M, You C, Tian R Machine Learning-Based Approaches for Prediction of Patients' Functional Outcome and Mortality after Spontaneous Intracerebral Hemorrhage. J Pers Med. 2022 Jan 14;12(1). pii: 112. doi: 10.3390/jpm12010112.
Menon G, Johnson SE, Hegde A, Rathod S, Nayak R, Nair R Neutrophil to lymphocyte ratio - A novel prognostic marker following spontaneous intracerebral haemorrhage. Clin Neurol Neurosurg. 2021 Jan;200:106339. doi: 10.1016/j.clineuro.2020.106339. Epub 2020 Oct 28.
Morotti A, Arba F, Boulouis G, Charidimou A Noncontrast CT markers of intracerebral hemorrhage expansion and poor outcome: A meta-analysis. Neurology. 2020 Oct 6;95(14):632-643. doi: 10.1212/WNL.0000000000010660. Epub 2020 Aug 26.
Tseng WC, Wang YF, Wang TG, Hsiao MY Early spot sign is associated with functional outcomes in primary intracerebral hemorrhage survivors. BMC Neurol. 2021 Mar 20;21(1):131. doi: 10.1186/s12883-021-02146-3.
Wang J, Wang W, Liu Y, Zhao X Associations Between Levels of High-Sensitivity C-Reactive Protein and Outcome After Intracerebral Hemorrhage. Front Neurol. 2020 Oct 6;11:535068. doi: 10.3389/fneur.2020.535068. eCollection 2020.
Xie H, Ma S, Wang X, Zhang X Noncontrast computer tomography-based radiomics model for predicting intracerebral hemorrhage expansion: preliminary findings and comparison with conventional radiological model. Eur Radiol. 2020 Jan;30(1):87-98. doi: 10.1007/s00330-019-06378-3. Epub 2019 Aug 5.
Capital's Funds for Health Improvement and Research
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.