Clinical trial NCT04202770 - References

Anxiety Disorders — Focused Ultrasound and Exosomes to Treat Depression, Anxiety, and Dementias

Citation(s)

•   Bandelow B, Michaelis S
  Epidemiology of anxiety disorders in the 21st century. Dialogues Clin Neurosci. 2015 Sep;17(3):327-35.
•   Boshuizen MCS, Steinberg GK
  Stem Cell-Based Immunomodulation After Stroke: Effects on Brain Repair Processes. Stroke. 2018 Jun;49(6):1563-1570. doi: 10.1161/STROKEAHA.117.020465. Epub 2018 May 3. Review.
•   Botteron KN, Raichle ME, Drevets WC, Heath AC, Todd RD
  Volumetric reduction in left subgenual prefrontal cortex in early onset depression. Biol Psychiatry. 2002 Feb 15;51(4):342-4.
•   Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP, Churchill R, Watanabe N, Nakagawa A, Omori IM, McGuire H, Tansella M, Barbui C
  Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet. 2009 Feb 28;373(9665):746-58. doi: 10.1016/S0140-6736(09)60046-5. Review.
•   Coupé P, Manjón JV, Lanuza E, Catheline G
  Lifespan Changes of the Human Brain In Alzheimer's Disease. Sci Rep. 2019 Mar 8;9(1):3998. doi: 10.1038/s41598-019-39809-8.
•   Detante O, Rome C, Papassin J
  How to use stem cells for repair in stroke patients. Rev Neurol (Paris). 2017 Nov;173(9):572-576. doi: 10.1016/j.neurol.2017.09.003. Epub 2017 Oct 21. Review.
•   Doeppner TR, Bähr M, Hermann DM, Giebel B
  Concise Review: Extracellular Vesicles Overcoming Limitations of Cell Therapies in Ischemic Stroke. Stem Cells Transl Med. 2017 Nov;6(11):2044-2052. doi: 10.1002/sctm.17-0081. Epub 2017 Sep 23. Review.
•   Drevets WC, Savitz J, Trimble M
  The subgenual anterior cingulate cortex in mood disorders. CNS Spectr. 2008 Aug;13(8):663-81. Review.
•   Ferrari AJ, Charlson FJ, Norman RE, Patten SB, Freedman G, Murray CJ, Vos T, Whiteford HA
  Burden of depressive disorders by country, sex, age, and year: findings from the global burden of disease study 2010. PLoS Med. 2013 Nov;10(11):e1001547. doi: 10.1371/journal.pmed.1001547. Epub 2013 Nov 5.
•   Hebron ML, Lonskaya I, Moussa CE
  Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of a-synuclein in Parkinson's disease models. Hum Mol Genet. 2013 Aug 15;22(16):3315-28. doi: 10.1093/hmg/ddt192. Epub 2013 May 10.
•   Jalbrzikowski M, Larsen B, Hallquist MN, Foran W, Calabro F, Luna B
  Development of White Matter Microstructure and Intrinsic Functional Connectivity Between the Amygdala and Ventromedial Prefrontal Cortex: Associations With Anxiety and Depression. Biol Psychiatry. 2017 Oct 1;82(7):511-521. doi: 10.1016/j.biopsych.2017.01.008. Epub 2017 Jan 17.
•   Lozano AM, Mayberg HS, Giacobbe P, Hamani C, Craddock RC, Kennedy SH
  Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression. Biol Psychiatry. 2008 Sep 15;64(6):461-7. doi: 10.1016/j.biopsych.2008.05.034. Epub 2008 Jul 18.
•   Mah L, Szabuniewicz C, Fiocco AJ
  Can anxiety damage the brain? Curr Opin Psychiatry. 2016 Jan;29(1):56-63. doi: 10.1097/YCO.0000000000000223. Review.
•   Mayberg H
  Depression, II: localization of pathophysiology. Am J Psychiatry. 2002 Dec;159(12):1979.
•   Mayberg HS, Brannan SK, Mahurin RK, Jerabek PA, Brickman JS, Tekell JL, Silva JA, McGinnis S, Glass TG, Martin CC, Fox PT
  Cingulate function in depression: a potential predictor of treatment response. Neuroreport. 1997 Mar 3;8(4):1057-61.
•   Mayberg HS, Liotti M, Brannan SK, McGinnis S, Mahurin RK, Jerabek PA, Silva JA, Tekell JL, Martin CC, Lancaster JL, Fox PT
  Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness. Am J Psychiatry. 1999 May;156(5):675-82.
•   Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C, Schwalb JM, Kennedy SH
  Deep brain stimulation for treatment-resistant depression. Neuron. 2005 Mar 3;45(5):651-60.
•   Mayberg HS
  Defining the neural circuitry of depression: toward a new nosology with therapeutic implications. Biol Psychiatry. 2007 Mar 15;61(6):729-30.
•   Mayberg HS
  Limbic-cortical dysregulation: a proposed model of depression. J Neuropsychiatry Clin Neurosci. 1997 Summer;9(3):471-81. Review.
•   Mayberg HS
  Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment. Br Med Bull. 2003;65:193-207. Review.
•   Mayberg HS
  Modulating limbic-cortical circuits in depression: targets of antidepressant treatments. Semin Clin Neuropsychiatry. 2002 Oct;7(4):255-68. Review.
•   Mayberg HS
  Positron emission tomography imaging in depression: a neural systems perspective. Neuroimaging Clin N Am. 2003 Nov;13(4):805-15. Review.
•   Mayberg HS
  Targeted electrode-based modulation of neural circuits for depression. J Clin Invest. 2009 Apr;119(4):717-25. doi: 10.1172/JCI38454. Review.
•   McDannold N, Vykhodtseva N, Hynynen K
  Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med Biol. 2008 May;34(5):834-40. doi: 10.1016/j.ultrasmedbio.2007.10.016. Epub 2008 Jan 22.
•   Montgomery SA, Baldwin DS, Riley A
  Antidepressant medications: a review of the evidence for drug-induced sexual dysfunction. J Affect Disord. 2002 May;69(1-3):119-40. Review.
•   Pagan, F
  , Valadez, E., Torres-Yaghi, Y., Falconer, R., Mills, R., Rogers, S., Wilmarth, B., Hebron, M., & Moussa, C. (2016) Effects of nilotinib on safety in open-label phase I clinical trial in Parkinson's disease with dementia and Lewy body dementia. Movement Disorders, 31(2).
•   Riva-Posse P, Choi KS, Holtzheimer PE, Crowell AL, Garlow SJ, Rajendra JK, McIntyre CC, Gross RE, Mayberg HS
  A connectomic approach for subcallosal cingulate deep brain stimulation surgery: prospective targeting in treatment-resistant depression. Mol Psychiatry. 2018 Apr;23(4):843-849. doi: 10.1038/mp.2017.59. Epub 2017 Apr 11.
•   Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, Niederehe G, Thase ME, Lavori PW, Lebowitz BD, McGrath PJ, Rosenbaum JF, Sackeim HA, Kupfer DJ, Luther J, Fava M
  Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006 Nov;163(11):1905-17.
•   Sarmah D, Agrawal V, Rane P, Bhute S, Watanabe M, Kalia K, Ghosh Z, Dave KR, Yavagal DR, Bhattacharya P
  Mesenchymal Stem Cell Therapy in Ischemic Stroke: A Meta-analysis of Preclinical Studies. Clin Pharmacol Ther. 2018 Jun;103(6):990-998. doi: 10.1002/cpt.927. Epub 2017 Dec 14.
•   Setiawan E, Attwells S, Wilson AA, Mizrahi R, Rusjan PM, Miler L, Xu C, Sharma S, Kish S, Houle S, Meyer JH
  Association of translocator protein total distribution volume with duration of untreated major depressive disorder: a cross-sectional study. Lancet Psychiatry. 2018 Apr;5(4):339-347. doi: 10.1016/S2215-0366(18)30048-8. Epub 2018 Feb 26.
•   Stonesifer C, Corey S, Ghanekar S, Diamandis Z, Acosta SA, Borlongan CV
  Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms. Prog Neurobiol. 2017 Nov;158:94-131. doi: 10.1016/j.pneurobio.2017.07.004. Epub 2017 Jul 23. Review.
•   Sussman ES, Steinberg GK
  A Focused Review of Clinical and Preclinical Studies of Cell-Based Therapies in Stroke. Neurosurgery. 2017 Sep 1;64(CN_suppl_1):92-96. doi: 10.1093/neuros/nyx329.
•   Suzuki E, Fujita D, Takahashi M, Oba S, Nishimatsu H
  Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular Disease. Adv Exp Med Biol. 2017;998:179-185. doi: 10.1007/978-981-10-4397-0_12. Review.
•   Tapiola T, Alafuzoff I, Herukka SK, Parkkinen L, Hartikainen P, Soininen H, Pirttilä T
  Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. Arch Neurol. 2009 Mar;66(3):382-9. doi: 10.1001/archneurol.2008.596.
•   Targosz-Gajniak MG, Siuda JS, Wicher MM, Banasik TJ, Bujak MA, Augusciak-Duma AM, Opala G
  Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia. J Neurol Sci. 2013 Dec 15;335(1-2):58-63. doi: 10.1016/j.jns.2013.08.023. Epub 2013 Aug 27.
•   Toyoshima A, Yasuhara T, Date I
  Mesenchymal Stem Cell Therapy for Ischemic Stroke. Acta Med Okayama. 2017 Aug;71(4):263-268. doi: 10.18926/AMO/55302. Review.
•   Yuan D, Zhao Y, Banks WA, Bullock KM, Haney M, Batrakova E, Kabanov AV
  Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain. Biomaterials. 2017 Oct;142:1-12. doi: 10.1016/j.biomaterials.2017.07.011. Epub 2017 Jul 10.
•   Yucel K, McKinnon M, Chahal R, Taylor V, Macdonald K, Joffe R, Macqueen G
  Increased subgenual prefrontal cortex size in remitted patients with major depressive disorder. Psychiatry Res. 2009 Jul 15;173(1):71-6. doi: 10.1016/j.pscychresns.2008.07.013. Epub 2009 May 21.

Focused Ultrasound Delivery of Exosomes for Treatment of Refractory Depression, Anxiety, and Neurodegenerative Dementias

Details for clinical trial NCT04202770