NCT02846129 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Butwick AJ, Carvalho B, El-Sayed YY
Risk factors for obstetric morbidity in patients with uterine atony undergoing caesarean delivery. Br J Anaesth. 2014 Oct;113(4):661-8. doi: 10.1093/bja/aeu150. Epub 2014 Jun 6.
Marino T, Goudas LC, Steinbok V, Craigo SD, Yarnell RW
The anesthetic management of triplet cesarean delivery: a retrospective case series of maternal outcomes. Anesth Analg. 2001 Oct;93(4):991-5.
Rouse DJ, MacPherson C, Landon M, Varner MW, Leveno KJ, Moawad AH, Spong CY, Caritis SN, Meis PJ, Wapner RJ, Sorokin Y, Miodovnik M, Carpenter M, Peaceman AM, O'Sullivan MJ, Sibai BM, Langer O, Thorp JM, Ramin SM, Mercer BM; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Blood transfusion and cesarean delivery. Obstet Gynecol. 2006 Oct;108(4):891-7. Erratum in: Obstet Gynecol. 2006 Dec;108(6):1556.
Trojner-Bregar A, Tul N, Verdenik I, Novak Z, Blickstein I
Puerperal morbidity following repeat cesarean delivery in twin pregnancies. Arch Gynecol Obstet. 2013 Sep;288(3):551-4. doi: 10.1007/s00404-013-2818-8. Epub 2013 Mar 28.
Walker MC, Murphy KE, Pan S, Yang Q, Wen SW
Adverse maternal outcomes in multifetal pregnancies. BJOG. 2004 Nov;111(11):1294-6.

Incidence of Complications Associated With Anesthesia in Multiple Gestation Undergoing Cesarean Delivery: A Retrospective Review

Clinical trial NCT02846129 - References