NCT04367818 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Anannamcharoen S, Cheeranont P, Boonya-usadon C
Local perianal nerve block versus spinal block for closed hemorrhoidectomy: a ramdomized controlled trial. J Med Assoc Thai. 2008 Dec;91(12):1862-6.
de Beer DA, Thomas ML
Caudal additives in children--solutions or problems? Br J Anaesth. 2003 Apr;90(4):487-98. Review.
Gabrielli F, Cioffi U, Chiarelli M, Guttadauro A, De Simone M
Hemorrhoidectomy with posterior perineal block: experience with 400 cases. Dis Colon Rectum. 2000 Jun;43(6):809-12.
Gopal DV
Diseases of the rectum and anus: a clinical approach to common disorders. Clin Cornerstone. 2002;4(4):34-48. Review.
Kaban OG, Yazicioglu D, Akkaya T, Sayin MM, Seker D, Gumus H
Spinal anaesthesia with hyperbaric prilocaine in day-case perianal surgery: randomised controlled trial. ScientificWorldJournal. 2014;2014:608372. doi: 10.1155/2014/608372. Epub 2014 Oct 14.
Luck AJ, Hewett PJ
Ischiorectal fossa block decreases posthemorrhoidectomy pain: randomized, prospective, double-blind clinical trial. Dis Colon Rectum. 2000 Feb;43(2):142-5.
Nyström PO, Derwinger K, Gerjy R
Local perianal block for anal surgery. Tech Coloproctol. 2004 Mar;8(1):23-6.
Zhang Y, Bao Y, Li L, Shi D
The effect of different doses of chloroprocaine on saddle anesthesia in perianal surgery. Acta Cir Bras. 2014 Jan;29(1):66-70. doi: 10.1590/S0102-86502014000100010.

Could Peri-anal Block be Effective as Caudal Block in Trans-anal Pull-through Surgery for Children With Hirschsprung Disease??. A Randomized Controlled Trial.

Details for clinical trial NCT04367818

Clinical trial NCT04367818 - References