NCT06066632 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Hussain M, Hanna M, Griffin BP, Conic J, Patel J, Fava AM, Watson C, Phelan DM, Jellis C, Grimm RA, Rodriguez LL, Schoenhagen P, Hachamovitch R, Jaber WA, Cremer PC, Collier P
Aortic Valve Calcium in Patients With Transthyretin Cardiac Amyloidosis: A Pro
Hussan et al
Aortic Valve Calcium Score Cut-Offs Used To Identify Hemodynamically Severe Aortic Stenosis May Not Apply In Patients With Cardiac Amyloidosis. ACC.20 World Congress of Cardiology (https://www.jacc.org/doi/abs/10.1016/S0735-1097%2820%2932791-1)

Analysis of Calcium Score Values of Severe Aortic Stenosis in Patients With and Without Cardiac Amyloidosis (CAUSATIVE Study)

Clinical trial NCT06066632 - References