Clinical trial NCT02873351 - References

Age-related Macular Degeneration — A Safety and Efficacy Study of Carbidopa-levodopa in Patients With Macular Degeneration

Citation(s)

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  Mining Retrospective Data for Virtual Prospective Drug Repurposing: L-DOPA and Age-related Macular Degeneration. Am J Med. 2016 Mar;129(3):292-8. doi: 10.1016/j.amjmed.2015.10.015. Epub 2015 Oct 30.
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  VISUAL FUNCTION MEASURES IN EARLY AND INTERMEDIATE AGE-RELATED MACULAR DEGENERATION. Retina. 2016 May;36(5):1021-31. doi: 10.1097/IAE.0000000000001002.
•   Falk T, Congrove NR, Zhang S, McCourt AD, Sherman SJ, McKay BS
  PEDF and VEGF-A output from human retinal pigment epithelial cells grown on novel microcarriers. J Biomed Biotechnol. 2012;2012:278932. doi: 10.1155/2012/278932. Epub 2012 Apr 2.
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•   Finger RP, Chong E, McGuinness MB, Robman LD, Aung KZ, Giles G, Baird PN, Guymer RH
  Reticular Pseudodrusen and Their Association with Age-Related Macular Degeneration: The Melbourne Collaborative Cohort Study. Ophthalmology. 2016 Mar;123(3):599-608. doi: 10.1016/j.ophtha.2015.10.029. Epub 2015 Dec 8.
•   Hongyang Zhang; Nizar Saleh Abdelfattah; David S Boyer; Srinivas R Sadda, Longitudinal Quantitative OCT Analysis of Drusen in the Fellow Eye of Patients with Unilateral Neovascular Age-Related Macular Degeneration, ARVO Annual Meeting Abstract, 2015
  
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  Inflammation and its role in age-related macular degeneration. Cell Mol Life Sci. 2016 May;73(9):1765-86. doi: 10.1007/s00018-016-2147-8. Epub 2016 Feb 6. Review.
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•   Nowacka B, Lubinski W, Honczarenko K, Potemkowski A, Safranow K
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•   Owsley C, McGwin G Jr, Clark ME, Jackson GR, Callahan MA, Kline LB, Witherspoon CD, Curcio CA
  Delayed Rod-Mediated Dark Adaptation Is a Functional Biomarker for Incident Early Age-Related Macular Degeneration. Ophthalmology. 2016 Feb;123(2):344-51. doi: 10.1016/j.ophtha.2015.09.041. Epub 2015 Oct 30.
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•   Sinemet package insert (FDA approved)
  
•   Standaert, D
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Pilot Study of L-DOPA Safety and Tolerability in Patients With AMD, and Proof of Concept That L-DOPA Improves Surrogate Biomarkers in Patients With Moderate to Advanced AMD

Details for clinical trial NCT02873351