Acute Pain — Diagnostic Performance of Low-Dose CT for Acute Abdominal Conditions
Citation(s)
Ahn S, Park SH, Lee KH How to demonstrate similarity by using noninferiority and equivalence statistical testing in radiology research. Radiology. 2013 May;267(2):328-38. doi: 10.1148/radiol.12120725.
Brady SL, Trout AT, Somasundaram E, Anton CG, Li Y, Dillman JR Improving Image Quality and Reducing Radiation Dose for Pediatric CT by Using Deep Learning Reconstruction. Radiology. 2021 Jan;298(1):180-188. doi: 10.1148/radiol.2020202317. Epub 2020 Nov 17.
Brenner DJ, Hall EJ Computed tomography--an increasing source of radiation exposure. N Engl J Med. 2007 Nov 29;357(22):2277-84. doi: 10.1056/NEJMra072149. No abstract available.
Hsieh JL, E ; Nett, B.; Tang, J.; Thibault JB.; Sahney, S. A new era of image reconstruction: TrueFidelity. Technical white paper on deep learning image reconstruction. 2019.
Kabir SA, Kabir SI, Sun R, Jafferbhoy S, Karim A How to diagnose an acutely inflamed appendix; a systematic review of the latest evidence. Int J Surg. 2017 Apr;40:155-162. doi: 10.1016/j.ijsu.2017.03.013. Epub 2017 Mar 6.
Komperød M, Rudjord AL, Skuterud L, Dyve JE Radiation Doses from the Environment. Calculations of the Public's Exposure to Radiation from the Environment in Norway. Strålevern Rapport 2015:11 Østerås: Norwegian Radiation Protection Authority 2015.
Mongan J, Moy L, Kahn CE Jr Checklist for Artificial Intelligence in Medical Imaging (CLAIM): A Guide for Authors and Reviewers. Radiol Artif Intell. 2020 Mar 25;2(2):e200029. doi: 10.1148/ryai.2020200029. eCollection 2020 Mar. No abstract available.
Njolstad T, Schulz A, Godt JC, Brogger HM, Johansen CK, Andersen HK, Martinsen ACT Improved image quality in abdominal computed tomography reconstructed with a novel Deep Learning Image Reconstruction technique - initial clinical experience. Acta Radiol Open. 2021 Apr 9;10(4):20584601211008391. doi: 10.1177/20584601211008391. eCollection 2021 Apr.
Pan X, Sidky EY, Vannier M Why do commercial CT scanners still employ traditional, filtered back-projection for image reconstruction? Inverse Probl. 2009 Jan 1;25(12):1230009. doi: 10.1088/0266-5611/25/12/123009.
Solomon J, Lyu P, Marin D, Samei E Noise and spatial resolution properties of a commercially available deep learning-based CT reconstruction algorithm. Med Phys. 2020 Sep;47(9):3961-3971. doi: 10.1002/mp.14319. Epub 2020 Jul 6.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
