Acute Myocardial Infarction — Sleep Habits and AMI and Gensini Score
Citation(s)
Buxton OM, Marcelli E Short and long sleep are positively associated with obesity, diabetes, hypertension, and cardiovascular disease among adults in the United States. Soc Sci Med. 2010 Sep;71(5):1027-36. doi: 10.1016/j.socscimed.2010.05.041. Epub 2010 Jun 16.
Campos H, Siles X Siesta and the risk of coronary heart disease: results from a population-based, case-control study in Costa Rica. Int J Epidemiol. 2000 Jun;29(3):429-37.
Cappuccio FP, Cooper D, D'Elia L, Strazzullo P, Miller MA Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur Heart J. 2011 Jun;32(12):1484-92. doi: 10.1093/eurheartj/ehr007. Epub 2011 Feb 7. Review.
Kobayashi D, Takahashi O, Deshpande GA, Shimbo T, Fukui T Association between weight gain, obesity, and sleep duration: a large-scale 3-year cohort study. Sleep Breath. 2012 Sep;16(3):829-33. doi: 10.1007/s11325-011-0583-0. Epub 2011 Sep 3.
Sharma M, Sawhney JP, Panda S Sleep quality and duration - potentially modifiable risk factors for Coronary Artery Disease? Indian Heart J. 2014 Nov-Dec;66(6):565-8. doi: 10.1016/j.ihj.2014.10.412. Epub 2014 Nov 4.
Taheri S, Lin L, Austin D, Young T, Mignot E Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004 Dec;1(3):e62. Epub 2004 Dec 7.
Wang D, Ruan W, Chen Z, Peng Y, Li W Shift work and risk of cardiovascular disease morbidity and mortality: A dose-response meta-analysis of cohort studies. Eur J Prev Cardiol. 2018 Aug;25(12):1293-1302. doi: 10.1177/2047487318783892. Epub 2018 Jun 22.
Yang WS, Fu WX, Wang X, Deng Q, Wang L, Wang LY, Zhao H, Fan WY, Huang SX Comprehensive assessments of long-term sleep habits in epidemiological study: Validity and reliability of sleep factors questionnaire (SFQ) among Chinese women. J Psychosom Res. 2017 Apr;95:12-18. doi: 10.1016/j.jpsychores.2017.02.005. Epub 2017 Feb 10.
Effects of Sleep Habits on Acute Myocardial Infarction Risk and Severity of Coronary Artery Disease in Chinese Population
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.