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Effects of EED on Zn Absorption and Retention in Children From a MNP — ZEED2  

Zinc Deficiency Clinical Trial

Official title:
Effects of Environmental Enteric Dysfunction (EED) on Zinc (Zn) Absorption and Retention in Young Children: Study 2 - Absorption of Zn From a Multi-micronutrient Powder (MNP)

Clinical Trial Summary

The overall objective is to determine the impact of EED on total daily zinc absorption of young Bangladeshi children (18-24 months of age) in an austere setting with high rates of diarrhea, stunting, and micro-nutrient deficiencies..

Clinical Trial Description

Participating children are screened for EED using the lactulose:mannitol ratio test and assigned to one of two groups: +EED or -EED. After assignment to one of the two groups, proposed subjects will be randomized to one of four supplement groups: Micronutrient powder (MNP) with 15 mg Zn, MNP with 10 mg Zn, MNP with 5 mg Zn, and MNP with 0 mg Zn. Children will receive the supplement once with a meal on Day 8 of the study. Absorption of zinc from the supplement and from other non-supplemented meals will be determined using zinc stable isotope technology. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02758444
Study type Interventional
Source University of Colorado, Denver
Contact
Status Completed
Phase N/A
Start date November 2015
Completion date February 2019
View Details
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