Clinical Trials Logo

Clinical Trial Summary

The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of mass zinc fortification programs.


Clinical Trial Description

The objectives of the present study are to determine whether plasma zinc concentration changes in response to additional zinc consumption, as provided by zinc-fortified cereal-based complementary foods fed to adult men (fortified at a level consistent with currently proposed levels). The following specific steps will be completed:

1. Zinc-fortified breads prepared from zinc-fortified wheat flour will be developed with assistance from experts in food technology.

2. A four-week feeding trial will be implemented to assess the change in plasma zinc concentration among young adult men who receive: a) bread fortified with a moderate amount of zinc and a liquid vitamin preparation between meals; b) bread fortified with a large amount zinc and a liquid vitamin preparation between meals; c) non-zinc-fortified bread and a liquid vitamin preparation between meals [negative control group]; and d) non-zinc-fortified bread and a zinc-containing liquid vitamin preparation between meals [positive control group]. ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention


Related Conditions & MeSH terms


NCT number NCT00944723
Study type Interventional
Source University of California, Davis
Contact
Status Completed
Phase Phase 4
Start date August 2009
Completion date February 2010

See also
  Status Clinical Trial Phase
Not yet recruiting NCT03353662 - Sub Regional Micronutrient Survey in Ethiopia
Completed NCT02126293 - Correction of Zinc Deficiency in Children With Chronic Kidney Disease and Kidney Transplant Phase 3
Terminated NCT01472211 - Water-based Zinc Intervention Trial in Zinc Deficient Children Phase 0
Completed NCT01061307 - An Efficacy Trial of Iron, Zinc and Vitamin A Fortified Rice in Children in Satun, Thailand Phase 0
Recruiting NCT03421314 - Effect of Zinc and Selenium Supplementation on HIV+ Individuals on Antiretroviral Treatment. N/A
Completed NCT02241330 - Efficacy of Zn Biofortified Wheat in Improving Zn Status in Indian School Children With Low Zn Status N/A
Completed NCT02292303 - Clinical Trial to Determine the Bioavailability of Three Different Zinc Preparations N/A
Completed NCT01221129 - Zinc and the Synthesis of Zinc Binding Proteins (Protocol B) N/A
Completed NCT04632771 - Nutritional Status and Bouillon Use in Northern Ghana
Recruiting NCT05236374 - Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc N/A
Completed NCT02758444 - Effects of EED on Zn Absorption and Retention in Children From a MNP N/A
Completed NCT02760095 - Effects of EED on Zn Absorption and Retention in Children From a Standard Dose
Completed NCT02233764 - Effect of Iron/Zinc-Biofortified Pearl Millet on Growth and Immunity in Children Aged 12-18 Months in India N/A
Recruiting NCT05527899 - Zinc Intervention in Elderly for Prevention of Pneumonia Phase 2/Phase 3
Terminated NCT04983667 - Zinc-AA Supplementation During Pregnancy & Lactation to Assess Effects on ASD Prevalence in Offspring N/A
Completed NCT03293641 - Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya N/A
Completed NCT05778383 - Zinc Supplementation Impact in Acute COVID-19 Clinical Outcomes Phase 4
Completed NCT04559152 - Zinc Supplementation During Pregnancy: Analysis of Maternal Serum Zinc, Cord Blood Osteocalcin and Neonatal Birth Length N/A
Completed NCT01062347 - A Novel Bio-marker of Zinc Status Phase 1
Recruiting NCT05085834 - Zinc Effect on Inflammation and Cardiovascular Risk in HIV Early Phase 1