Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT05413993 |
Other study ID # |
PBMSF |
Secondary ID |
|
Status |
Completed |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
March 10, 2022 |
Est. completion date |
May 20, 2022 |
Study information
Verified date |
June 2022 |
Source |
University of Nove de Julho |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
Changes in salivary parameters, such as decreased flow, changes in pH and composition, can
lead to changes in oral health. Saliva is responsible for the homeostasis of the oral cavity
and is therefore directly related to the occurrence of caries, periodontitis, fungal and
bacterial infections. These situations compromise the quality of life of the population and
for this reason prevention and treatment strategies need to be studied and developed.
Photobiomodulation is an alternative that has been increasingly practiced by health
professionals. It consists of the application of light to a biological system that is capable
of inducing a photochemical process, mainly in the mitochondria, thus stimulating the
production of energy in the form of adenosine triphosphate (ATP), which can increase cellular
metabolism and produce effects. as analgesia and tissue regeneration. In dentistry, studies
using photobiomodulation have shown promise in improving some salivary parameters. This study
aimed to compare the action of infrared light on salivary flow and pH, using two application
techniques: extraoral (G1) and intra and extraoral (G2), with the application interval
between the two techniques being 7 days
Description:
This is a quasi-experimental clinical study evaluating the flow and salivary pH of healthy
adults. The study was carried out with 20 adult patients at the Nove de Julho University.
This study aimed to compare the action of infrared light on salivary flow and pH, using two
application techniques: extraoral (G1) and intra and extraoral (G2), with the application
interval between the two techniques being 7 days. The sample consisted of 20 healthy adults,
who participated in both groups, thus being the actual control in the evaluations. Stimulated
saliva was collected in both groups before and immediately after light application. In G1, a
cluster with 3 spots was used, at a wavelength of 808 nanometers, power of 120 mW, with 24J
of energy on the extraoral surface, for 67 seconds, in the region of the parotid gland,
region of the submandibular and sublingual glands bilaterally, totaling 4 application
regions, with total deposited energy of 96 joules. In G2, the laser was applied for 60
seconds, in 2 intraoral and 2 extraoral points in the region of the parotid glands
bilaterally, as well as 1 intraoral and 1 extraoral point in the regions of the submandibular
and sublingual glands (totaling 16 points), with a central wavelength of 808 nm; continuous
operating mode; power of 100mW; with an aperture diameter of 0.354 cm (with spacer); radiant
energy of 6J per point, totaling 96 joules of energy.