Xerosis Cutis Clinical Trial
Official title:
Comparison of Efficacy and Safety Between Moisturising Cream Containing 12% Ammonium Lactate AND 10% Urea in Geriatric With Xerosis Cutis: Double Blind Randomised Controlled Trial
This study aims to compare the efficacy and safety between moisturizing cream containing 12% ammonium lactate and 10% urea in geriatric with xerosis cutis. A double-blind randomized controlled trial with matching paired subject was conducted on 40 residents of a nursing home in Jakarta. Specified symptom sum score (SRRC), skin capacitance (SCap), transepidermal water loss (TEWL), and side effects were measured at baseline, week-2 and week-4 after therapy, and week-5 one week after therapy cessation. After a week of preconditioning, each subject received two different moisturizing creams to be applied on separate lower limbs.
Dry skin or xerosis cutis is widely known skin health issue in geriatric population with prevalence rate ranges between 29.5 - 85.5%. One of the internal etiological factors is decreased production of natural moisturizing factor as a humectant. Application of moisturizer is the mainstay treatment. Moisturizer with humectant property, like lactate and urea, could restore skin hydration and barrier dysfunction. This study aims to compare the efficacy and safety between moisturizing cream containing 12% ammonium lactate and 10% urea in geriatric with xerosis cutis. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05046015 -
Comparison Dry Foot Skin Between Diabetic and Non-diabetic Subjects and the Effects of Two Cosmetic Foot Care Products
|
N/A | |
Completed |
NCT02216526 -
Skin Health and Effectiveness of Standardized Skin Care Regimens in Nursing Home Residents
|
N/A | |
Completed |
NCT03824886 -
Enhancing SKIN Health and Safety in Aged CARE
|
N/A | |
Completed |
NCT02557698 -
Effectiveness of Using an Oil Bath Additive
|
N/A | |
Completed |
NCT03093597 -
Skin Barrier Biophysical Properties and Clinical Appearance After Moisturizer in Dry Skin
|
N/A | |
Active, not recruiting |
NCT03815305 -
Effect of Centella Asiatica on Xerotic Skin in Diabetes Mellitus Type 2
|
Phase 4 | |
Recruiting |
NCT05639933 -
Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors
|
Phase 2 | |
Completed |
NCT04253704 -
Effects of 2% IDL Lotion on Skin Hydration and Transepidermal Water Loss in Females With Dry Skin
|
Phase 1/Phase 2 | |
Completed |
NCT06178367 -
Effectiveness and Safety of Topical Hyaluronic Acid of Different Molecular Weights in Xerotic Skin Treatment
|
Phase 3 |