Feasibility Study for Fibroblast Autologous Skin Grafts

Status Recruiting

Clinical Trial Summary

This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.

Clinical Trial Description

To change the skin identity investigators propose to take skin cells from a person's own sole or palm (these are called "autologous skin fibroblasts"), multiply them in the lab, inject the cells (now called a "graft") back into the same person but at a different site of skin like the buttock, and then eventually remove the injected cells to see if they caused the skin to change. Investigators hope that information from this study will help with problems like skin break-down in patients with amputations and prosthetics. The skin at their stump was not meant to withstand the pressure and friction of prosthetics and this study is the first step in trying to convert stump skin to palm/sole-like skin. ;

Study Design

Related Conditions & MeSH terms

Wounds and Injuries

Clinical Trial Details

NCT number	NCT01964859
Study type	Interventional
Source	Johns Hopkins University
Contact	Ruizhi Wang
Phone	410-502-7546
Email	rwang53@jhmi.edu
Status	Recruiting
Phase	Phase 2
Start date	January 7, 2015
Completion date	November 1, 2028

View Details

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