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Wounds and Injuries clinical trials

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NCT ID: NCT03696927 Completed - Clinical trials for Spinal Cord Injuries

Active Powered Prosthesis (APEX) for Spinal Cord Injury

Start date: August 29, 2018
Phase: N/A
Study type: Interventional

The Active Powered Prosthesis (APEX) (AbiliTech Medical Inc., Minneapolis, MN) is a proof-of-concept shoulder-elbow-wrist device intended to provide non-invasive active powered robotic assistive movement to upper extremities. The objective of this study is to perform focus groups with users and clinicians to evaluate a proof of concept active powered assistance device.

NCT ID: NCT03691532 Completed - Clinical trials for Spinal Cord Injuries

Postprandial Lipid Tracer and Exercise in Spinal Cord Injury

PPLT
Start date: May 30, 2018
Phase: N/A
Study type: Interventional

This study investigates the effect of upper extremity exercise on postprandial lipemia (PPL) in persons with spinal cord injury (SCI). Participants are measured at rest and fed a standardized meal following seated rest (CON) or arm cycling exercise (ACE). The meal is infused with "stable isotope lipid tracers" that allow for determination of the end fates of the fat in the meal.

NCT ID: NCT03691272 Completed - Headache Clinical Trials

rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head

TOPiCS-rTMS
Start date: April 15, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of this study is to investigate the treatment effect of repetitive transcranial magnetic stimulation in patients with a history of both persistent post-traumatic headache and post-concussion symptoms. In this double-blind, sham-controlled, concealed allocation, randomized clinical trial, 20 patients aged 18-65 yrs will be recruited from the Calgary Brain Injury Program (CBIP) and the Calgary Headache Assessment and Management Program (CHAMP) / Calgary Chronic Pain Centre, Calgary, Alberta, Canada. Patients will engage in a two-week rTMS treatment protocol (10 treatments) and will be followed for 6 months after therapy.

NCT ID: NCT03690726 Completed - Spinal Cord Injury Clinical Trials

The Effects of rTMS in Rehabilitation Following Spinal Cord Injury

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

The project will investigate whether repetitive transcranial magnetic stimulation (rTMS) can be used to potentiate/prime spinal cord injured patients' nervous systems for more intense rehabilitation exercise of longer duration - thus leading to greater recovery of motion function. The technique, in which a magnetic coil is positioned above the scalp and forms a magnetic field that activates the desired center of the brain (eg motor cortex), is used in clinical practice for the treatment of a number of disorders. However, although a combination of rTMS and gait training in SCI patients previously has proven beneficial, it is unknown whether additional functional gains can be achieved by combining rTMS and supervised, high-intensity resistance training. In this project, 30 newly-admitted patients will be recruited and randomized to receive either active rTMS and strength training (n = 15) or sham (imitated) rTMS + strength training, in parallel with standard care. The investigators hypothesize that the active rTMS group will have superior gains in locomotor function and muscle mass, compared to the sham group.

NCT ID: NCT03690219 Completed - Clinical trials for Acute Injury in Mountain Biking

Prevalence of Acute Injuries in Amateur and Elite Mountain Bikers

Start date: September 11, 2017
Phase:
Study type: Observational

The investigators intented to assess the prevalence of acute injuries in amateur and elite mountain bikers.

NCT ID: NCT03689023 Completed - Clinical trials for Spinal Cord Injuries

Health Promotion and Cardiovascular Risk Reduction Among People With Spinal Cord Injury

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

This study is a controlled pragmatic implementation study in clinical practice, with a primary focus on cardiovascular risk reduction through adherence to behavioral interventions related to physical activity and healthy diet.The intervention is interdisciplinary, multimodal and patient activating and uses the existing setting and work flows at the clinic, ensuring that the patients receive education about cardiovascular risk factors, physical activity and healthy diet through a systematic approach including targeted patient education.

NCT ID: NCT03688984 Completed - Insomnia Clinical Trials

Treatment of Insomnia for Adolescents With Mild Traumatic Brain Injury

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

A substantial number of children and adolescents sustain a mild traumatic brain injury (mTBI) each year. Although research supports that the vast majority of youth will recover quickly and return to normal functioning, some adolescents continue to report problems long after the injury. Disturbed sleep, notably trouble with sleep onset and sleep maintenance, is a frequently reported problem in those with slow recovery from a mTBI. Poor sleep is also associated with cognitive complaints, mood disturbance, and lower quality of life. Despite the identification of sleep disturbance as a problem associated with slow recovery, there are very few treatment options. Cognitive-behavioural therapy for insomnia (CBT-I) has shown promise in children and adolescents as an effective treatment for sleep disturbance, although it has yet to be applied to the adolescent mTBI population who also present with sleep problems. The objective of this study is to examine the treatment of sleep disturbance using cognitive-behavioural therapy for insomnia (CBT-I) in those adolescents who have a protracted recovery from their mTBI. This represents a novel treatment option for this patient population and is anticipated to improve outcomes and quality of life.

NCT ID: NCT03687840 Completed - Clinical trials for Diabetic Polyneuropathy

Spatio-Temporal Gait Parameters and Gait Symmetry In Diabetic Lower Extremity Burn Injury.

Start date: February 14, 2017
Phase: N/A
Study type: Interventional

This study evaluated the spatio-temporal gait parameters and gait symmetry in individuals with lower extremity burn injury due to diabetic polyneuropathy. Study group consisted of 14 subjects with unilateral lower extremity burn injuries due to diabetic polyneuropathy and control group consisted of 14 subjects with only diabetic polyneuropathy.

NCT ID: NCT03686904 Completed - Wound Infection Clinical Trials

Investigation of a Novel Wound Gel to Improve Wound Healing in Chronic Wounds

Start date: November 19, 2018
Phase: Phase 4
Study type: Interventional

This is a prospective, randomized, double-blinded, single site study examining the impact of a biofilm-based treatment of chronic wounds of the lower extremity. 200 subjects will be enrolled in this study. Benzalkonium solution wound irrigation and Benzalkonium wound gel will be compared to standard of care wound preparation and dressing (NS wound irrigation and hydrocolloid gel) following local debridement. Wounds will be assessed maximum of 12 weeks with a minimum of 4 follow up visits. Patients will be recruited from the general wound clinic population. No enticement will be offered and participation will be completely voluntary. At enrollment and at each follow up visit the wound will be assessed for size (length, width, and depth), signs of infection or irritation, qualitative and quantitative cultures will be taken before and after debridement, patients will be assessed for compliance to the treatment protocol, satisfaction with their treatment, any adverse effects of the treatment, and hospitalizations since last assessment. It is anticipated that enrollment and completion of the study will take 1 year.

NCT ID: NCT03683303 Completed - Wound Clinical Trials

The Effects of Educational Program Using APP on Pre-Discharge Knowledge, Skills and Anxiety of Wound Care

Start date: March 2016
Phase: N/A
Study type: Interventional

The purposes of this study were to understand the effects of mhealth App on wound care knowledge, wound care skills, and anxiety related to dressing change when compared to traditional health education before patients discharged from hospital.