Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.

Wound Infection Clinical Trial

Official title:

Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06220344
• Other study ID #: HITEC-IMS-01-2022
• Status: Completed
• Phase: Phase 2/Phase 3
• Start date: December 2, 2022
• Est. completion date: March 3, 2023

Study information

• Verified date: January 2024
• Source: HITEC-Institute of Medical Sciences
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other co-morbidities like Diabetes, Anemia, etc. which can make the results biased. The main questions it aims to answer are:

• Do the iodine solutions are enough to counter the infections caused by resistant strains of bacteria?

• What is the efficacy and efficiency of honey dressing in wound care?

Participants will be tasked to

• Ensure strict follow-up in the hospital dressing room

• Half of the participants will apply common iodine solution dressing and the other half will be applied honey dressing.

Researchers will compare Iodine dressing (Control group) with Honey dressing (Experimental group) to see if Honey dressing is better in the prevention of post-surgery wound infection and if it is cost-efficient and its efficacy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: March 3, 2023
• Est. primary completion date: March 3, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 12 Years to 50 Years

Eligibility

Inclusion Criteria:

Patients with sterile/clean post-surgical wounds are admitted in general surgery, neurosurgery, orthopedic, and gynecology wards and require follow-up dressings.

Exclusion Criteria:

1. Patients with:

• Anemia

• BMI>30

• Local Infection in wound area.

• Venous leg ulcers

• Diabetes

• Immunocompromised (Oncological patients)

2. Patient under negative pressure therapy

Related Conditions & MeSH terms

• Communicable Diseases
• Infections
• Surgical Wound
• Surgical Wound Infection
• Wound Dehiscence
• Wound Infection
• Wound Surgical
• Wounds and Injuries

Intervention

Biological:
• Honey Dressing
Honey Dressing will be applied from the 1st Post-Op day till the fully healed wound, which is described as no dehiscence, no exudate, no warmth, and sutures removed.

Drug:
• Iodine Dressing
Iodine Dressing will be applied from the 1st Post-Op day till the fully healed wound, which is described as no dehiscence, no exudate, no warmth, and sutures removed.

Locations

Country	Name	City	State
Pakistan	Heavy Industry Taxila Hospital	Rawalpindi	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
HITEC-Institute of Medical Sciences

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Signs of Wound Infection	Presence of exudate, warmth, pus, erythema, dehiscence, contact bleeding, and any systemic sign like fever, rash, and myalgia.	3rd day, 7th day, 15th day.