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Wound Heal clinical trials

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NCT ID: NCT05921513 Not yet recruiting - Wound Heal Clinical Trials

Effects of StellaLife Oral Care Recovery Kit on Palatal Wound Healing After Free Gingival Graft

Start date: July 15, 2023
Phase: N/A
Study type: Interventional

This study looks to compare the clinical effects of StellaLife VEGA Oral Care Kit with chlorhexidine mouth-rinse on patient comfort, wound healing, wound epithelialization, bacterial levels, and colonization of the wounds.

NCT ID: NCT05915169 Recruiting - Pressure Ulcer Clinical Trials

The Effects of Topical Haemoglobin Spray in Pressure Ulcer

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

A prospective randomised controlled experimental study was planned to compare the effects of pressure sore dressing using topical haemoglobin and traditional gauze dressing using saline on the healing process and cost of pressure sores in patients with pressure sores.

NCT ID: NCT05905861 Not yet recruiting - Postoperative Pain Clinical Trials

Scalpel Versus Diathermy for Transverse Abdominal Incision in First Elective Caesarean Section

Start date: July 2023
Phase: N/A
Study type: Interventional

The objective of this study will be to compare two methods of skin incisions during the first caesarean section (CS), that is scalpel and diathermy, assessing differences in blood loss during incision, incisional time, total surgery time, post-operative pain, wound healing, complications, and cosmetic outcomes.

NCT ID: NCT05883098 Completed - Diabetic Foot Clinical Trials

SDRM® vs. Collagen for Diabetic Foot Ulcers

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Supra SDRM® is FDA-cleared as a dressing for treating partial and full-thickness wounds. It is a dermal substitute that provides a barrier and an ECM-like structure to help accelerate wound healing. SUPRA SDRM® has 510k approval for partial and full-thickness wounds and has shown promising results in preliminary animal studies. The purpose of this clinical evaluation is to collect and compare outcomes data from patients with UT 1A diabetic foot ulcers treated with a commercially available dermal substitute, Supra SDRM®, as compared to an advanced standard of care (Fibracol Plus). Patient outcomes, including time to heal, healing by 12 weeks, direct costs, and infection rate, will be compared at the end of the study.

NCT ID: NCT05871190 Completed - Wound Heal Clinical Trials

The Effects Of I-PRF On Gingivectomy and Gingivoplasty

Start date: August 23, 2021
Phase: N/A
Study type: Interventional

The study aims to evaluate the effects of injectable platelet-rich fibrin (I-PRF) applications on early wound healing after gingivectomy and gingivoplasty surgery. In this randomized controlled single-blind study, gingivectomy and gingivoplasty surgeries were performed on 46 patients. The postoperative I-PRF-applied surgery areas were compared with control regions. The surgical areas were stained with Mira-2 tone and evaluated in the ImageJ program. Wound healing was evaluated by using the Modified Manchester Scar (MMS) scale and Landry, Turnbull, and Howley (LTH) index. Vascular endothelial growth factor (VEGF) and fibroblast growth factor 10 (FGF-10) concentrations were assessed by enzyme-linked immunoabsorbent assay (ELISA). The seven-day Visual Analog Scale was used to assess pain level. Considering the results found, I-PRF applications revealed positive effects on epithelial wound healing after gingivectomy and gingivoplasty operations.

NCT ID: NCT05853237 Completed - Wound Heal Clinical Trials

Class iv Versus Class Iiib Laser Therapy on Median Sternotomy Healing After Coronary Artery Bybass Graft

wounds
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

LASER therapy is potent physiotherapy modalities, providing better sternotomy healing for patients who have undergone CABG surgery, compared with traditional wound care management alone. HLLT and LLLT were found to be the most effective methods for sternotomy healing post-CABG surgery, with HLLT offering superior performance in the case of the high deep penetration and significance less time needed to deliver the same joules/ cm compared to LLLT used for the wound site.

NCT ID: NCT05850819 Completed - Wound Heal Clinical Trials

Effectiveness of Gelatamp in Wound Healing After Teeth Extraction: A Randomized Clinical Trial

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

This study compares the effectiveness of Gelatamp for intraoral wound closure after extraction of mandibular teeth.

NCT ID: NCT05840406 Not yet recruiting - Postoperative Pain Clinical Trials

Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The primary purpose of this study is to determine whether the addition of a TAP block to standard analgesia after the cesarean delivery will impact postoperative wound healing and attenuate postoperative stress and immune response. Random allocation of participants in 3 groups: group SA (standard analgesia), group L (TAP block with levobupivacaine), and group D (TAP block with levobupivacaine + dexmedetomidine). All participants will undergo elective cesarean section through Pfannestiel incision under spinal anesthesia. They will receive standard postoperative pain management with acetaminophen, nonsteroidal anti-inflammatory drugs, and tramadol. Groups L and D will additionally receive bilateral ultrasound-guided TAP block with 20 ml 0,25% levobupivacaine or with 20 ml 0,25% levobupivacaine with the addition of 0,5 μg/kg dexmedetomidine. TAP block will be performed in the theatre immediately after the cesarean delivery. Venous blood samples will be collected before the surgery and on the third postoperative day. Complete blood count and serum cortisol levels will be measured. REEDA scale will be used for assessing wound healing.

NCT ID: NCT05839158 Completed - Wound Heal Clinical Trials

Evaluation of the Effect of HFMT in Promoting Donor-site Wound Healing

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Autologous hair transplantation involves follicle extraction, trimming, and implantation. Follicle trimming improves efficiency and postoperative appearance, resulting in the discarded tissue known as hair follicle-derived microtissue (HFMT). In a clinical case, HFMT homogenate was applied to the FUE donor area wound, resulting in reduced pain, relief from itching, and faster healing compared to conventional treatment. This study aims to compare the effects of HFMT on FUE donor area wound healing.

NCT ID: NCT05802602 Recruiting - Wound Heal Clinical Trials

Porcine Membrane vs Bovine Wound Dressing in Human Tooth Extraction Sites

Start date: April 16, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare porcine collagen membrane and bovine collagen wound dressing in human tooth extraction sites. The outcomes measured will be soft tissue thickness changes as well as bone density changes.