Wilson Disease Clinical Trial
Official title:
Observational Clinical Study of Anti-AAV Seroprevalence in Subjects With Ornithine Transcarbamylase Deficiency, Glycogen Storage Disorder Type Ia, and Wilson Disease
The objective of this observational study is to evaluate the seroprevalence of anti-AAV antibodies in subjects with Ornithine Transcarbamylase (OTC) deficiency, Glycogen Storage Disease Type Ia (GSDIa), and Wilson Disease
The study is primarily designed to follow a virtual model, in which Screening will take place over a telephone/video call. The study will comprise a single home health visit, either on the same day as Screening or within 30 days of enrollment. A safety follow-up may occur up to 5 days after Day 1 assessments are completed. ;
Status | Clinical Trial | Phase | |
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Completed |
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Copper and Molybdenum Balance in Participants With Wilson Disease Treated With ALXN1840
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Phase 2 | |
Completed |
NCT03539952 -
Trientine Tetrahydrochloride (TETA 4HCL) for the Treatment of Wilson's Disease
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Phase 3 | |
Active, not recruiting |
NCT04884815 -
Study of UX701 Gene Transfer for the Treatment of Wilson Disease
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Phase 1/Phase 2 | |
Not yet recruiting |
NCT03659331 -
A Controlled Study of Potential Therapeutic Effect of Oral Zinc in Manifesting Carriers of Wilson Disease
|
N/A | |
Recruiting |
NCT05687474 -
Baby Detect : Genomic Newborn Screening
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Completed |
NCT04965571 -
Clinical Features and Outcome of Wilson's Disease With Generalized Epilepsy in Chinese Patients
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Terminated |
NCT05047523 -
Study of ALXN1840 Versus Standard of Care in Pediatric Participants With Wilson Disease
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Phase 3 | |
Completed |
NCT04526210 -
Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy Participants
|
Phase 1 | |
Completed |
NCT00004338 -
Study of Zinc for Wilson Disease
|
Phase 4 | |
Enrolling by invitation |
NCT03655223 -
Early Check: Expanded Screening in Newborns
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Completed |
NCT02273596 -
Efficacy and Safety Study of WTX101 (ALXN1840) in Adult Wilson Disease Patients
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Phase 2 | |
Completed |
NCT02763215 -
The Assessment of Copper Parameters in Wilson Disease Participants on Standard of Care Treatment
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||
Recruiting |
NCT05444127 -
Oral Health and Wilson's Disease: SOMAWI
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Completed |
NCT04408300 -
Study of Retinal Vascular Parameters in Patients With Wilson's Disease
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N/A | |
Active, not recruiting |
NCT05783687 -
Real World Evidence Study in Subjects With Wilson's Disease
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Completed |
NCT03867526 -
Establishment of Human Cellular Disease Models for Wilson Disease
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Enrolling by invitation |
NCT03589820 -
Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson's Disease-related Liver Failure
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N/A | |
Completed |
NCT04526197 -
Phase 1 Study of ALXN1840 on the Metabolism of a CYP2C9 Substrate in Healthy Participants.
|
Phase 1 | |
Not yet recruiting |
NCT06430359 -
Circadian Variation of Urinary Copper Excretion in Wilson Disease Patients
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||
Completed |
NCT04910581 -
rTMS in Wilson Disease Dysarthria
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N/A |