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Clinical Trial Summary

Hypothesis: substitution of nebulized 3% NaCl (HS) for the standard normal saline (NS) used in bronchodilator therapy for acute viral wheezing in all children under age 6 years will provide superior symptom relief leading to decreased admission rates from the Emergency Department.

The study will test the efficacy of frequent doses of inhaled bronchodilator co-administered with either 3% hypertonic saline (HS, study group) or 0.9% normal saline (NS, control group) in a prospective, double blind, randomized controlled, multi-centre clinical trial of children under age 6 years presenting to the ED with acute viral-associated wheezing.


Clinical Trial Description

the brief summary captures the essence of the study ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01868932
Study type Interventional
Source Queen's University
Contact
Status Withdrawn
Phase Phase 2
Start date October 2013
Completion date November 2013

See also
  Status Clinical Trial Phase
Completed NCT02743663 - The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
Recruiting NCT02496468 - Pediatric Arm of DZL All Age Asthma Cohort
Withdrawn NCT02319564 - Combined Glucocorticoid Adrenergic Therapy For Wheezy Preschool Children Phase 4