Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation

Weaning Failure Clinical Trial

Official title:

Implantation of a Multidisciplinary Ventilator-weaning Protocol in a Intensive Care Unit of Teaching Hospital of Federal University of Uberlandia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01482429
• Other study ID #: Desmame
• Status: Completed
• Phase: N/A
• First received: November 27, 2011
• Last updated: January 27, 2013
• Start date: January 2011
• Est. completion date: January 2012

Study information

• Verified date: January 2013
• Source: Federal University of Uberlandia
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

Prolongation of mechanical ventilation poses serious personal and financial threats to healthcare consumers.

The investigators objectives are create and implement an multidisciplinary evidenced-based ventilator-weaning protocol to assess whether a systematic approach compared with the physician's judgment only decreases time spent on the ventilator, complications of mechanical ventilation and length of stay in critical care unit.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 235
• Est. completion date: January 2012
• Est. primary completion date: January 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• remain in mechanical ventilation for more than 24 hours

• begin weaning from mechanical ventilation

Exclusion Criteria:

• admitted in the unit already in weaning from mechanical ventilation

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Complication of Respirator [Ventilator]
• Weaning Failure

Intervention

Other:
• Multidisciplinary weaning-ventilator protocol
We implemented a multidisciplinary protocol for weaning from mechanical ventilation.This consist of a daily screening for readiness, performing a spontaneous breathing test, evaluation of signs of intolerance and decision on extubation.

Locations

Country	Name	City	State
Brazil	Federal University of Uberlandia	Uberlandia	Minas Gerais

Sponsors (1)

Lead Sponsor	Collaborator
Federal University of Uberlandia

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mortality		length of ICU stay (days)	Yes
Primary	Duration of Weaning From Mechanical Ventilation		days	Yes
Primary	Duration of Mechanical Ventilation		days	Yes
Primary	Length of Intensive Care Unit Stay		days	Yes