Walking Clinical Trial
Official title:
Frontal Lobe Oxyhemoglobin Levels in Patients With Lower Extremity Burns Assessed Using a Functional Near-Infrared Spectroscopy Device During Usual Walking: A Pilot Study
Investigators investigate the patterns of cortical activation using the NIRST in patients with peripheral neurological injury caused by lower extremity burns.
Understanding the mechanisms associated with locomotor networks may be of benefit for
rehabilitation of burn victims with neurological locomotor deficits. However, the effects of
peripheral neurological injury on locomotor network remains unknown. A wearable functional
near-infrared spectroscopy (fNIRS) device has been developed for studying cortical
hemodynamics. Changes in cortical activity has not previously been documented in patients
with burn injury.
Investigators assessed 15 patients with lower extremity burns and 11 healthy controls.
Investigators measured walking-related cortical activity using an fNIRS device at baseline
and during usual walking.
Cortical activity was measured by evaluating relative changes in oxyhemoglobin level. The
NIRST Analysis Tool v2.1 was utilized to analyze fNIRS data in a MATLAB environment.
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