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Vomiting clinical trials

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NCT ID: NCT00886236 Completed - Postoperative Pain Clinical Trials

Study of the Effect of the Drug Gabapentin on Postoperative Pain and Incidence of Postoperative Nausea and Vomiting

Start date: February 2008
Phase: N/A
Study type: Interventional

The purpose of this research study is to evaluate the drug gabapentin (Neurontin®) for its ability to reduce postoperative pain, the need for morphine-like pain medication, and the severity and frequency of postoperative nausea and vomiting in laparoscopic gastric bypass surgery patients.

NCT ID: NCT00880191 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Gabapentin in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy

Start date: April 2009
Phase: Phase 3
Study type: Interventional

RATIONALE: Gabapentin may prevent or reduce delayed nausea and vomiting caused by chemotherapy. It is not yet known whether gabapentin is more effective than a placebo in preventing nausea and vomiting. PURPOSE: This randomized phase III trial is studying the side effects of gabapentin and to see how well it works compared with a placebo in preventing nausea and vomiting in patients receiving chemotherapy.

NCT ID: NCT00878228 Completed - Clinical trials for Nausea and Vomiting, Postoperative

Antiemetic Prophylaxis for Postdischarge Nausea and Vomiting After Hip Arthroscopy

PDNV
Start date: April 2009
Phase: Phase 4
Study type: Interventional

The study is a randomized placebo controlled trial to determine whether repeated postoperative prophylactic ondansetron ("Zofran") administration will prevent postoperative and/or postdischarge nausea and vomiting in patients undergoing ambulatory hip arthroscopy. Ondansetron will be administered in the intra- and post-operative period. These individuals will be followed on postoperative days 1, 2, and 3. It is hypothesized that the incidence of postdischarge nausea and vomiting (PDNV) will be significantly decreased by postoperative prophylactic administration of multiple doses of ondansetron (Zofran).

NCT ID: NCT00869973 Terminated - Emesis Clinical Trials

Aprepitant in the Prevention of Delayed Emesis Induced by Cyclophosphamide Plus Anthracyclines in Breast Cancer Patients

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The aim of the study is to compare efficacy and tolerability of aprepitant versus dexamethasone in the prevention of delayed emesis induced by moderately emetogenic chemotherapy (cyclophosphamide plus anthracyclines) in breast cancer patients.

NCT ID: NCT00869310 Terminated - Emesis Clinical Trials

Aprepitant in the Prevention of Cisplatin-induced Delayed Emesis

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The aim of the study is to compare efficacy and tolerability of aprepitant plus dexamethasone versus metoclopramide plus dexamethasone in the prevention of cisplatin-induced delayed emesis in patients that received aprepitant, palonosetron and dexamethasone before chemotherapy administration for the prevention of acute emesis.

NCT ID: NCT00861523 Terminated - Clinical trials for Hyperemesis Gravidarum

Does Thiamine Help Vomiting and Nausea in Pregnancy?

Start date: February 2009
Phase: Phase 3
Study type: Interventional

There are different treatments for nausea and vomiting in pregnancy. According to the ACOG recommendations, promethazine is the first line of parenteral treatment after oral treatment had failed. Thiamine is given to prevent wernicke encephalopathy. This research try to find out whether thiamine helps the vomiting and nausea as well, by comparing the response to thiamine and promethazine in women who suffer from nausea and vomiting in pregnancy.

NCT ID: NCT00858949 Completed - Clinical trials for Postoperative Nausea and Vomiting

Costs of Postoperative Nausea and Vomiting in Ambulatory Surgery Patients

Start date: August 2008
Phase: N/A
Study type: Observational

This is an observational study with the goal of determining the costs of nausea and vomiting in ambulatory patients after surgery from the US societal perspective.

NCT ID: NCT00835965 Unknown status - Nausea Clinical Trials

Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries

Start date: February 2009
Phase: N/A
Study type: Interventional

The combination of aprepitant and lower dose dexamethasone is superior to aprepitant alone with respect to the proportion of patients with a complete response (no vomiting and no use of rescue therapy) during 24 hours after the placement of last suture/staple.

NCT ID: NCT00828295 Completed - Clinical trials for Postoperative Nausea and Vomiting

Safety and Efficacy of Palonosetron IV to Prevent Postoperative Nausea and Vomiting in Pediatric Patients

Start date: August 2008
Phase: Phase 3
Study type: Interventional

The objective of the study is to assess the safety and efficacy of two doses of IV palonosetron each administered as a single dose for the prevention of postoperative nausea and vomiting through 72 hours postoperatively in children aged 28 days up to 16 years inclusive undergoing surgical procedures requiring general endotracheal inhalation anesthesia.

NCT ID: NCT00825071 Completed - Clinical trials for Postoperative Nausea and Vomiting

Dexamethasone for Postoperative Nausea and Vomiting

Start date: November 2007
Phase: Phase 4
Study type: Interventional

The investigators want to test the efficacy of these anesthetic antiemetic measures collectively with or without ondansetron or dexamethasone, in the prevention of postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy.